SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iuz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.39A	1oe1A-1iuzA: 3.9	1oe1A-1iuzA: 14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE2_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1iuz	PLASTOCYANIN (Ulva pertusa)	5 / 5	HIS A 37 CYH A 84 PRO A 86 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 4.9A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.73A	1oe2A-1iuzA: 6.5	1oe2A-1iuzA: 14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA501_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.42A	1oe3A-1iuzA: 3.8	1oe3A-1iuzA: 14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VM1_A_TAZA504_1 (BETA-LACTAMASE SHV-1)	1iuz	PLASTOCYANIN (Ulva pertusa)	3 / 3	ASP A 61 TYR A 62 GLU A 85	None	0.87A	1vm1A-1iuzA: undetectable	1vm1A-1iuzA: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQD_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.42A	2fqdA-1iuzA: 3.4	2fqdA-1iuzA: 13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQE_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.38A	2fqeA-1iuzA: 0.0	2fqeA-1iuzA: 13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQF_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.37A	2fqfA-1iuzA: 3.4	2fqfA-1iuzA: 13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FQG_A_CUA601_0 (BLUE COPPER OXIDASE CUEO)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.36A	2fqgA-1iuzA: 3.6	2fqgA-1iuzA: 13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1337_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.40A	2xxgA-1iuzA: 6.3	2xxgA-1iuzA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	1iuz	PLASTOCYANIN (Ulva pertusa)	5 / 5	HIS A 37 CYH A 84 PRO A 86 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 4.9A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.78A	2xxgC-1iuzA: 6.6	2xxgC-1iuzA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MSS_D_STID1_2 (TYROSINE-PROTEIN KINASE ABL1)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 6	VAL A 70 VAL A 98 VAL A 82 ILE A 27	None	0.94A	3mssD-1iuzA: undetectable	3mssD-1iuzA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EF3_A_CUA1001_0 (BLUE COPPER OXIDASE CUEO)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 4	HIS A 37 CYH A 84 HIS A 87 MET A 92	CU A 100 ( 3.2A) CU A 100 ( 2.1A) CU A 100 ( 3.1A) CU A 100 ( 2.6A)	0.34A	4ef3A-1iuzA: 3.3	4ef3A-1iuzA: 12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GWZ_D_010D6_0 (N-[(5-METHYLISOXAZOL -3-YL)CARBONYL]ALANY L-L-VALYL-N~1~-((1R, 2Z)-4-(BENZYLOXY)-4- OXO-1-{[(3R)-2-OXOPY RROLIDIN-3-YL]METHYL }BUT-2-ENYL)-L-LEUCI NAMIDE PEDV MAIN PROTEASE)	1iuz	PLASTOCYANIN (Ulva pertusa)	3 / 3	MET A 92 HIS A 37 GLY A 7	CU A 100 ( 2.6A) CU A 100 ( 3.2A) None	0.87A	5gwzB-1iuzA: 0.0	5gwzB-1iuzA: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	1iuz	PLASTOCYANIN (Ulva pertusa)	4 / 8	TYR A 80 PHE A 41 PHE A 29 VAL A 21	None	1.01A	6huoC-1iuzA: undetectable 6huoD-1iuzA: 1.2	6huoC-1iuzA: 17.89 6huoD-1iuzA: 20.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.39A","1oe1A-1iuzA:3.9","1oe1A-1iuzA:14.98"],["1OE2_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1iuz","PLASTOCYANIN","Ulva pertusa",5,"HIS A  37;CYH A  84;PRO A  86;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 4.9A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.73A","1oe2A-1iuzA:6.5","1oe2A-1iuzA:14.98"],["1OE3_A_CUA501_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.42A","1oe3A-1iuzA:3.8","1oe3A-1iuzA:14.98"],["1VM1_A_TAZA504_1","BETA-LACTAMASE SHV-1","1iuz","PLASTOCYANIN","Ulva pertusa",3,"ASP A  61;TYR A  62;GLU A  85","None","0.87A","1vm1A-1iuzA:undetectable","1vm1A-1iuzA:17.42"],["2FQD_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.42A","2fqdA-1iuzA:3.4","2fqdA-1iuzA:13.14"],["2FQE_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.38A","2fqeA-1iuzA:0.0","2fqeA-1iuzA:13.14"],["2FQF_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.37A","2fqfA-1iuzA:3.4","2fqfA-1iuzA:13.14"],["2FQG_A_CUA601_0","BLUE COPPER OXIDASE CUEO","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.36A","2fqgA-1iuzA:3.6","2fqgA-1iuzA:13.14"],["2XXG_A_CUA1337_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.40A","2xxgA-1iuzA:6.3","2xxgA-1iuzA:15.69"],["2XXG_C_CUC1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","1iuz","PLASTOCYANIN","Ulva pertusa",5,"HIS A  37;CYH A  84;PRO A  86;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 4.9A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.78A","2xxgC-1iuzA:6.6","2xxgC-1iuzA:15.69"],["3MSS_D_STID1_2","TYROSINE-PROTEIN KINASE ABL1","1iuz","PLASTOCYANIN","Ulva pertusa",4,"VAL A  70;VAL A  98;VAL A  82;ILE A  27","None","0.94A","3mssD-1iuzA:undetectable","3mssD-1iuzA:19.29"],["4EF3_A_CUA1001_0","BLUE COPPER OXIDASE CUEO","1iuz","PLASTOCYANIN","Ulva pertusa",4,"HIS A  37;CYH A  84;HIS A  87;MET A  92"," CU A 100 ( 3.2A); CU A 100 ( 2.1A); CU A 100 ( 3.1A); CU A 100 ( 2.6A)","0.34A","4ef3A-1iuzA:3.3","4ef3A-1iuzA:12.07"],["5GWZ_D_010D6_0","N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE;PEDV MAIN PROTEASE","1iuz","PLASTOCYANIN","Ulva pertusa",3,"MET A  92;HIS A  37;GLY A   7"," CU A 100 ( 2.6A); CU A 100 ( 3.2A);None","0.87A","5gwzB-1iuzA:0.0","5gwzB-1iuzA:16.89"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","1iuz","PLASTOCYANIN","Ulva pertusa",4,"TYR A  80;PHE A  41;PHE A  29;VAL A  21","None","1.01A","6huoC-1iuzA:undetectable;6huoD-1iuzA:1.2","6huoC-1iuzA:17.89;6huoD-1iuzA:20.79"]]