SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	8 / 12	HIS A 48 TYR A 50 LEU A 199 ASP A 228 HIS A 442 ASP A 443 ASP A 596 ARG A 600	None None None None None None MLZ A 513 ( 4.9A) None	0.77A	1dedA-1iv8A: 29.5	1dedA-1iv8A: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	7 / 12	HIS A 48 TYR A 50 LEU A 199 GLU A 255 ASP A 443 ASP A 596 ARG A 600	None None None None None MLZ A 513 ( 4.9A) None	1.03A	1dedA-1iv8A: 29.5	1dedA-1iv8A: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_B_QPSB1501_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	9 / 12	HIS A 48 TYR A 50 LEU A 199 ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443 ARG A 600	None	0.79A	1dedB-1iv8A: 25.3	1dedB-1iv8A: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_X_BRLX504_1 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ILE A 631 GLY A 629 LEU A 29 LEU A 608 TYR A 25	None	1.30A	1fm6X-1iv8A: 0.0	1fm6X-1iv8A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_A_CHDA1503_0 (FERROCHELATASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	LEU A 713 PRO A 714 LEU A 699	None	0.47A	1hrkA-1iv8A: undetectable	1hrkA-1iv8A: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LHU_A_ESTA301_1 (SEX HORMONE-BINDING GLOBULIN)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	SER A 494 ASP A 483 ASN A 482 MET A 511 ILE A 507	None None None None MLZ A 508 ( 3.6A)	1.26A	1lhuA-1iv8A: 0.0	1lhuA-1iv8A: 14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MOG_A_RBFA200_1 (DODECIN)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	PHE A 552 TRP A 471 GLU A 470	None MLZ A 467 ( 3.4A) MLZ A 467 ( 3.8A)	1.10A	1mogA-1iv8A: 0.0	1mogA-1iv8A: 7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA735_1 (ALPHA AMYLASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	8 / 12	TYR A 50 HIS A 90 PHE A 193 ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.65A	1mxdA-1iv8A: 24.8	1mxdA-1iv8A: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_D_URFD2021_1 (URIDINE PHOSPHORYLASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	GLY A 232 MET A 384 ILE A 230 PRO A 236	None	1.01A	1rxcD-1iv8A: undetectable	1rxcD-1iv8A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_E_TFPE212_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	PHE A 116 LEU A 161 PHE A 118 SER A 110	None None None MLY A 111 ( 3.1A)	0.99A	1wrlE-1iv8A: undetectable	1wrlE-1iv8A: 9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XF1_B_ACTB1108_0 (C5A PEPTIDASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	GLY A 232 HIS A 229 ASN A 89 ILE A 230	None	0.89A	1xf1B-1iv8A: 2.1	1xf1B-1iv8A: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z95_A_198A501_2 (ANDROGEN RECEPTOR)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	LEU A 163 LEU A 127 LEU A 174 ILE A 125	None	0.89A	1z95A-1iv8A: 3.6	1z95A-1iv8A: 15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXC_A_P1ZA2001_1 (SERUM ALBUMIN)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	6 / 12	LEU A 343 LEU A 380 ALA A 369 ILE A 366 ILE A 334 ALA A 329	None None None None None MLZ A 326 ( 3.6A)	1.14A	2bxcA-1iv8A: 0.0	2bxcA-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_IMNA2003_1 (SERUM ALBUMIN)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 10	ARG A 70 LEU A 71 ILE A 82 HIS A 76 GLY A 79	None	1.47A	2bxqA-1iv8A: 0.0	2bxqA-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA4_A_ACHA546_0 (ACETYLCHOLINESTERASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	TYR A 352 PHE A 194 HIS A 229 GLY A 232	None	1.10A	2ha4A-1iv8A: undetectable	2ha4A-1iv8A: 20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P16_A_GG2A298_2 (COAGULATION FACTOR X (EC 3.4.21.6) (STUART FACTOR) (STUART-PROWER FACTOR))	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	ARG A 402 GLU A 296 GLN A 288	None	0.94A	2p16A-1iv8A: 0.0	2p16A-1iv8A: 16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNC_A_CLUA808_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	TYR A 274 ASP A 228 TYR A 50 HIS A 442	None	1.34A	2pncA-1iv8A: undetectable	2pncA-1iv8A: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	LEU A 713 PRO A 714 LEU A 699	None	0.55A	2po5B-1iv8A: undetectable	2po5B-1iv8A: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO7_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	LEU A 713 PRO A 714 LEU A 699	None	0.59A	2po7B-1iv8A: undetectable	2po7B-1iv8A: 19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA508_0 (CHORISMATE SYNTHASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 5	LEU A 339 ARG A 340 ALA A 329 ILE A 317	None None MLZ A 326 ( 3.6A) None	0.96A	2qhfA-1iv8A: 0.0	2qhfA-1iv8A: 17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W98_B_P1ZB1357_1 (PROSTAGLANDIN REDUCTASE 2)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	TYR A 115 LEU A 100 ASN A 97 ASP A 51	None	1.20A	2w98A-1iv8A: undetectable 2w98B-1iv8A: undetectable	2w98A-1iv8A: 19.76 2w98B-1iv8A: 19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_A_SAMA801_0 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ILE A 227 ASN A 89 GLY A 232 LEU A 266 TYR A 239	None	1.18A	2zw9A-1iv8A: 2.1	2zw9A-1iv8A: 25.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.92A	3abkA-1iv8A: 0.0 3abkJ-1iv8A: 0.0	3abkA-1iv8A: 20.68 3abkJ-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.92A	3ag3A-1iv8A: 0.0 3ag3J-1iv8A: 0.0	3ag3A-1iv8A: 20.68 3ag3J-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_A_ACRA5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.73A	3aicA-1iv8A: 5.5	3aicA-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_B_ACRB5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.70A	3aicB-1iv8A: 5.3	3aicB-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_C_ACRC5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	6 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443 TYR A 50	None	0.73A	3aicC-1iv8A: 6.9	3aicC-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_D_ACRD5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.80A	3aicD-1iv8A: 6.9	3aicD-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_E_ACRE5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.76A	3aicE-1iv8A: 6.9	3aicE-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_F_ACRF5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.72A	3aicF-1iv8A: 6.5	3aicF-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_G_ACRG5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.71A	3aicG-1iv8A: 6.5	3aicG-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_H_ACRH5044_1 (GLUCOSYLTRANSFERASE- SI)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.79A	3aicH-1iv8A: 5.1	3aicH-1iv8A: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_W_CHDW1059_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.90A	3asoN-1iv8A: 0.0 3asoW-1iv8A: 0.0	3asoN-1iv8A: 20.68 3asoW-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I9J_B_NCAB302_0 (ADP-RIBOSYL CYCLASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	LEU A 403 ASN A 281 SER A 458 PHE A 286	None	1.28A	3i9jB-1iv8A: 2.9	3i9jB-1iv8A: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M7R_A_VDXA425_2 (VITAMIN D3 RECEPTOR)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 9	PHE A 667 LEU A 713 ILE A 575 ARG A 643 TYR A 634	None None None None MLZ A 638 ( 3.6A)	1.44A	3m7rA-1iv8A: 0.0	3m7rA-1iv8A: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QJ7_A_SPMA264_1 (THYMIDYLATE SYNTHASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ALA A 75 LEU A 34 ASP A 223 ASP A 221	None None None MLY A 250 ( 4.3A)	0.98A	3qj7A-1iv8A: 0.0 3qj7D-1iv8A: 0.0	3qj7A-1iv8A: 16.76 3qj7D-1iv8A: 16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3O_A_DLUA399_1 (PFV INTEGRASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 PRO A 38 GLN A 84 ARG A 600	None	1.29A	3s3oA-1iv8A: 3.3	3s3oA-1iv8A: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEU_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4feuB-1iv8A: undetectable	4feuB-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEU_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.19A	4feuF-1iv8A: undetectable	4feuF-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.17A	4fevB-1iv8A: 0.0	4fevB-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4fevD-1iv8A: undetectable	4fevD-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.16A	4fevF-1iv8A: undetectable	4fevF-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.16A	4fewB-1iv8A: undetectable	4fewB-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4fewD-1iv8A: 0.0	4fewD-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.16A	4fewF-1iv8A: undetectable	4fewF-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEX_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4fexB-1iv8A: undetectable	4fexB-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA312_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	ARG A 7 HIS A 442 TYR A 35	None	1.28A	4fu9A-1iv8A: undetectable	4fu9A-1iv8A: 15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4gkhB-1iv8A: undetectable	4gkhB-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.17A	4gkhD-1iv8A: 0.0	4gkhD-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4gkhF-1iv8A: 0.0	4gkhF-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_G_KANG301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4gkhG-1iv8A: undetectable	4gkhG-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_J_KANJ301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.17A	4gkhJ-1iv8A: 0.0	4gkhJ-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_K_KANK301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4gkhC-1iv8A: undetectable 4gkhK-1iv8A: 0.0	4gkhC-1iv8A: 16.69 4gkhK-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKI_A_KANA301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.15A	4gkiA-1iv8A: undetectable	4gkiA-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKI_C_KANC301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 228 ASP A 596 ASP A 443 GLU A 255	None MLZ A 513 ( 4.9A) None None	1.16A	4gkiC-1iv8A: undetectable	4gkiC-1iv8A: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	GLY A 579 LEU A 573 ASN A 437 PHE A 276	None	1.03A	4m5mA-1iv8A: 0.2	4m5mA-1iv8A: 13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O0O_A_URFA303_1 (RRNA N-GLYCOSIDASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 5	TYR A 415 ASN A 278 TYR A 279 ILE A 418	None	1.28A	4o0oA-1iv8A: undetectable	4o0oA-1iv8A: 16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKW_A_198A1001_2 (ANDROGEN RECEPTOR)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	LEU A 163 LEU A 127 LEU A 174 ILE A 125	None	0.93A	4okwA-1iv8A: 3.5	4okwA-1iv8A: 15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTW_A_DB8A1101_2 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	LEU A 154 LEU A 100 ASN A 178	None None MLZ A 105 ( 4.3A)	0.64A	4otwA-1iv8A: undetectable	4otwA-1iv8A: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTJ_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	ASP A 628 LYS A 632 LEU A 568	None	1.03A	4ptjA-1iv8A: 0.0	4ptjA-1iv8A: 10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_A_ACTA1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 5	ARG A 430 GLY A 579 ALA A 578 GLY A 432	None	0.94A	4u9uA-1iv8A: 2.1	4u9uA-1iv8A: 15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U9U_B_ACTB1502_0 (NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 5	ARG A 430 GLY A 579 ALA A 578 GLY A 432	None	0.85A	4u9uB-1iv8A: undetectable	4u9uB-1iv8A: 15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YSH_B_GLYB402_0 (GLYCINE OXIDASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 5	GLU A 255 TYR A 50 ARG A 7 ARG A 226	None	1.49A	4yshB-1iv8A: 0.8	4yshB-1iv8A: 19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_A_SVRA205_1 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	LYS A 614 TYR A 637 LEU A 608 PHE A 605	None MLZ A 638 ( 4.0A) None None	1.08A	4yv5A-1iv8A: undetectable	4yv5A-1iv8A: 10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YV5_B_SVRB207_2 (BASIC PHOSPHOLIPASE A2 HOMOLOG 2)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	LYS A 614 TYR A 637 LEU A 608 PHE A 605	None MLZ A 638 ( 4.0A) None None	1.11A	4yv5B-1iv8A: 0.0	4yv5B-1iv8A: 10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.92A	5b1aA-1iv8A: 0.0 5b1aJ-1iv8A: 0.0	5b1aA-1iv8A: 20.68 5b1aJ-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.92A	5b3sA-1iv8A: 0.0 5b3sJ-1iv8A: undetectable	5b3sA-1iv8A: 20.68 5b3sJ-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B8I_C_FK5C201_1 (SERINE/THREONINE-PRO TEIN PHOSPHATASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	SER A 458 PRO A 461 PHE A 460 GLU A 463	None None MLY A 558 ( 4.4A) MLY A 558 ( 3.0A)	1.19A	5b8iA-1iv8A: 0.1	5b8iA-1iv8A: 19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_1 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ARG A 226 ASP A 228 GLU A 255 HIS A 442 ASP A 443	None	0.48A	5csyB-1iv8A: 7.3	5csyB-1iv8A: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_1 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	ASP A 394 ASP A 228 GLU A 255 HIS A 442 ASP A 443	MLY A 390 ( 3.8A) None None None None	0.84A	5csyB-1iv8A: 7.3	5csyB-1iv8A: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G48_A_1FLA1375_1 (DNA POLYMERASE III SUBUNIT BETA)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	LEU A 639 PRO A 714 ILE A 716 LEU A 642	MLZ A 638 ( 4.2A) None None MLZ A 638 ( 4.6A)	0.90A	5g48A-1iv8A: undetectable	5g48A-1iv8A: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGY_A_ERYA403_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 6	TYR A 274 ASP A 228 ILE A 253 TYR A 35	None	1.49A	5igyA-1iv8A: 2.5	5igyA-1iv8A: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 5	ILE A 125 PHE A 118 ARG A 192 THR A 198	None	1.18A	5z84N-1iv8A: 0.0 5z84W-1iv8A: 0.0	5z84N-1iv8A: 20.68 5z84W-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.91A	5zcpA-1iv8A: 0.0 5zcpJ-1iv8A: 0.0	5zcpA-1iv8A: 20.68 5zcpJ-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 7	ILE A 129 LEU A 181 TYR A 190 LEU A 104	None None None MLZ A 105 ( 4.3A)	0.92A	5zcqA-1iv8A: 0.0 5zcqJ-1iv8A: undetectable	5zcqA-1iv8A: 20.68 5zcqJ-1iv8A: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA610_0 (ALPHA-AMYLASE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	5 / 12	TYR A 50 HIS A 90 ASP A 228 HIS A 442 ASP A 443	None	0.50A	6ag0A-1iv8A: 20.8	6ag0A-1iv8A: 7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	LEU A 689 ASN A 711 LEU A 664	None	0.69A	6exiA-1iv8A: undetectable	6exiA-1iv8A: 7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_B_AM2B301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	HIS A 510 GLU A 517 ASP A 394 GLU A 393	None MLY A 390 ( 3.7A) MLY A 390 ( 3.8A) None	1.14A	6mn4B-1iv8A: 0.0	6mn4B-1iv8A: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_C_AM2C301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	ASP A 596 GLU A 517 ASP A 394 GLU A 393	MLZ A 513 ( 4.9A) MLY A 390 ( 3.7A) MLY A 390 ( 3.8A) None	1.17A	6mn4C-1iv8A: undetectable	6mn4C-1iv8A: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_C_AM2C301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	HIS A 510 GLU A 517 ASP A 394 GLU A 393	None MLY A 390 ( 3.7A) MLY A 390 ( 3.8A) None	1.24A	6mn4C-1iv8A: undetectable	6mn4C-1iv8A: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_D_AM2D301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	4 / 8	HIS A 510 GLU A 517 ASP A 394 GLU A 393	None MLY A 390 ( 3.7A) MLY A 390 ( 3.8A) None	1.19A	6mn4D-1iv8A: 0.0	6mn4D-1iv8A: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1iv8	MALTOOLIGOSYL TREHALOSE SYNTHASE (Sulfolobus acidocaldarius)	3 / 3	ARG A 430 PHE A 650 PHE A 276	None	0.81A	6nknC-1iv8A: 0.0 6nknJ-1iv8A: 0.0	6nknC-1iv8A: 16.13 6nknJ-1iv8A: 5.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",8,"HIS A  48;TYR A  50;LEU A 199;ASP A 228;HIS A 442;ASP A 443;ASP A 596;ARG A 600","None;None;None;None;None;None;MLZ A 513 ( 4.9A);None","0.77A","1dedA-1iv8A:29.5","1dedA-1iv8A:21.59"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",7,"HIS A  48;TYR A  50;LEU A 199;GLU A 255;ASP A 443;ASP A 596;ARG A 600","None;None;None;None;None;MLZ A 513 ( 4.9A);None","1.03A","1dedA-1iv8A:29.5","1dedA-1iv8A:21.59"],["1DED_B_QPSB1501_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",9,"HIS A  48;TYR A  50;LEU A 199;ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443;ARG A 600","None","0.79A","1dedB-1iv8A:25.3","1dedB-1iv8A:21.59"],["1FM6_X_BRLX504_1","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ILE A 631;GLY A 629;LEU A  29;LEU A 608;TYR A  25","None","1.30A","1fm6X-1iv8A:0.0","1fm6X-1iv8A:18.36"],["1HRK_A_CHDA1503_0","FERROCHELATASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"LEU A 713;PRO A 714;LEU A 699","None","0.47A","1hrkA-1iv8A:undetectable","1hrkA-1iv8A:19.72"],["1LHU_A_ESTA301_1","SEX HORMONE-BINDING GLOBULIN","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"SER A 494;ASP A 483;ASN A 482;MET A 511;ILE A 507","None;None;None;None;MLZ A 508 ( 3.6A)","1.26A","1lhuA-1iv8A:0.0","1lhuA-1iv8A:14.64"],["1MOG_A_RBFA200_1","DODECIN","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"PHE A 552;TRP A 471;GLU A 470","None;MLZ A 467 ( 3.4A);MLZ A 467 ( 3.8A)","1.10A","1mogA-1iv8A:0.0","1mogA-1iv8A:7.09"],["1MXD_A_ACRA735_1","ALPHA AMYLASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",8,"TYR A  50;HIS A  90;PHE A 193;ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.65A","1mxdA-1iv8A:24.8","1mxdA-1iv8A:21.05"],["1RXC_D_URFD2021_1","URIDINE PHOSPHORYLASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"GLY A 232;MET A 384;ILE A 230;PRO A 236","None","1.01A","1rxcD-1iv8A:undetectable","1rxcD-1iv8A:16.67"],["1WRL_E_TFPE212_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"PHE A 116;LEU A 161;PHE A 118;SER A 110","None;None;None;MLY A 111 ( 3.1A)","0.99A","1wrlE-1iv8A:undetectable","1wrlE-1iv8A:9.24"],["1XF1_B_ACTB1108_0","C5A PEPTIDASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"GLY A 232;HIS A 229;ASN A  89;ILE A 230","None","0.89A","1xf1B-1iv8A:2.1","1xf1B-1iv8A:23.38"],["1Z95_A_198A501_2","ANDROGEN RECEPTOR","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LEU A 163;LEU A 127;LEU A 174;ILE A 125","None","0.89A","1z95A-1iv8A:3.6","1z95A-1iv8A:15.55"],["2BXC_A_P1ZA2001_1","SERUM ALBUMIN","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",6,"LEU A 343;LEU A 380;ALA A 369;ILE A 366;ILE A 334;ALA A 329","None;None;None;None;None;MLZ A 326 ( 3.6A)","1.14A","2bxcA-1iv8A:0.0","2bxcA-1iv8A:22.47"],["2BXQ_A_IMNA2003_1","SERUM ALBUMIN","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A  70;LEU A  71;ILE A  82;HIS A  76;GLY A  79","None","1.47A","2bxqA-1iv8A:0.0","2bxqA-1iv8A:22.47"],["2HA4_A_ACHA546_0","ACETYLCHOLINESTERASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"TYR A 352;PHE A 194;HIS A 229;GLY A 232","None","1.10A","2ha4A-1iv8A:undetectable","2ha4A-1iv8A:20.78"],["2P16_A_GG2A298_2","COAGULATION FACTOR X (EC 3.4.21.6) (STUART FACTOR) (STUART-PROWER FACTOR)","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"ARG A 402;GLU A 296;GLN A 288","None","0.94A","2p16A-1iv8A:0.0","2p16A-1iv8A:16.15"],["2PNC_A_CLUA808_1","COPPER AMINE OXIDASE, LIVER ISOZYME","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"TYR A 274;ASP A 228;TYR A  50;HIS A 442","None","1.34A","2pncA-1iv8A:undetectable","2pncA-1iv8A:20.68"],["2PO5_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"LEU A 713;PRO A 714;LEU A 699","None","0.55A","2po5B-1iv8A:undetectable","2po5B-1iv8A:19.72"],["2PO7_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"LEU A 713;PRO A 714;LEU A 699","None","0.59A","2po7B-1iv8A:undetectable","2po7B-1iv8A:19.72"],["2QHF_A_ACTA508_0","CHORISMATE SYNTHASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LEU A 339;ARG A 340;ALA A 329;ILE A 317","None;None;MLZ A 326 ( 3.6A);None","0.96A","2qhfA-1iv8A:0.0","2qhfA-1iv8A:17.91"],["2W98_B_P1ZB1357_1","PROSTAGLANDIN REDUCTASE 2;PROSTAGLANDIN REDUCTASE 2","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"TYR A 115;LEU A 100;ASN A  97;ASP A  51","None","1.20A","2w98A-1iv8A:undetectable;2w98B-1iv8A:undetectable","2w98A-1iv8A:19.76;2w98B-1iv8A:19.76"],["2ZW9_A_SAMA801_0","LEUCINE CARBOXYL METHYLTRANSFERASE 2","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ILE A 227;ASN A  89;GLY A 232;LEU A 266;TYR A 239","None","1.18A","2zw9A-1iv8A:2.1","2zw9A-1iv8A:25.78"],["3ABK_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.92A","3abkA-1iv8A:0.0;3abkJ-1iv8A:0.0","3abkA-1iv8A:20.68;3abkJ-1iv8A:5.63"],["3AG3_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.92A","3ag3A-1iv8A:0.0;3ag3J-1iv8A:0.0","3ag3A-1iv8A:20.68;3ag3J-1iv8A:5.63"],["3AIC_A_ACRA5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.73A","3aicA-1iv8A:5.5","3aicA-1iv8A:22.47"],["3AIC_B_ACRB5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.70A","3aicB-1iv8A:5.3","3aicB-1iv8A:22.47"],["3AIC_C_ACRC5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",6,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443;TYR A  50","None","0.73A","3aicC-1iv8A:6.9","3aicC-1iv8A:22.47"],["3AIC_D_ACRD5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.80A","3aicD-1iv8A:6.9","3aicD-1iv8A:22.47"],["3AIC_E_ACRE5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.76A","3aicE-1iv8A:6.9","3aicE-1iv8A:22.47"],["3AIC_F_ACRF5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.72A","3aicF-1iv8A:6.5","3aicF-1iv8A:22.47"],["3AIC_G_ACRG5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.71A","3aicG-1iv8A:6.5","3aicG-1iv8A:22.47"],["3AIC_H_ACRH5044_1","GLUCOSYLTRANSFERASE-SI","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.79A","3aicH-1iv8A:5.1","3aicH-1iv8A:22.47"],["3ASO_W_CHDW1059_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.90A","3asoN-1iv8A:0.0;3asoW-1iv8A:0.0","3asoN-1iv8A:20.68;3asoW-1iv8A:5.63"],["3I9J_B_NCAB302_0","ADP-RIBOSYL CYCLASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LEU A 403;ASN A 281;SER A 458;PHE A 286","None","1.28A","3i9jB-1iv8A:2.9","3i9jB-1iv8A:16.48"],["3M7R_A_VDXA425_2","VITAMIN D3 RECEPTOR","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"PHE A 667;LEU A 713;ILE A 575;ARG A 643;TYR A 634","None;None;None;None;MLZ A 638 ( 3.6A)","1.44A","3m7rA-1iv8A:0.0","3m7rA-1iv8A:16.89"],["3QJ7_A_SPMA264_1","THYMIDYLATE SYNTHASE;THYMIDYLATE SYNTHASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ALA A  75;LEU A  34;ASP A 223;ASP A 221","None;None;None;MLY A 250 ( 4.3A)","0.98A","3qj7A-1iv8A:0.0;3qj7D-1iv8A:0.0","3qj7A-1iv8A:16.76;3qj7D-1iv8A:16.76"],["3S3O_A_DLUA399_1","PFV INTEGRASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;PRO A  38;GLN A  84;ARG A 600","None","1.29A","3s3oA-1iv8A:3.3","3s3oA-1iv8A:18.30"],["4FEU_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4feuB-1iv8A:undetectable","4feuB-1iv8A:16.69"],["4FEU_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.19A","4feuF-1iv8A:undetectable","4feuF-1iv8A:16.69"],["4FEV_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.17A","4fevB-1iv8A:0.0","4fevB-1iv8A:16.69"],["4FEV_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4fevD-1iv8A:undetectable","4fevD-1iv8A:16.69"],["4FEV_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.16A","4fevF-1iv8A:undetectable","4fevF-1iv8A:16.69"],["4FEW_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.16A","4fewB-1iv8A:undetectable","4fewB-1iv8A:16.69"],["4FEW_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4fewD-1iv8A:0.0","4fewD-1iv8A:16.69"],["4FEW_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.16A","4fewF-1iv8A:undetectable","4fewF-1iv8A:16.69"],["4FEX_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4fexB-1iv8A:undetectable","4fexB-1iv8A:16.69"],["4FU9_A_ACTA312_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"ARG A   7;HIS A 442;TYR A  35","None","1.28A","4fu9A-1iv8A:undetectable","4fu9A-1iv8A:15.06"],["4GKH_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4gkhB-1iv8A:undetectable","4gkhB-1iv8A:16.69"],["4GKH_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.17A","4gkhD-1iv8A:0.0","4gkhD-1iv8A:16.69"],["4GKH_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4gkhF-1iv8A:0.0","4gkhF-1iv8A:16.69"],["4GKH_G_KANG301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4gkhG-1iv8A:undetectable","4gkhG-1iv8A:16.69"],["4GKH_J_KANJ301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.17A","4gkhJ-1iv8A:0.0","4gkhJ-1iv8A:16.69"],["4GKH_K_KANK301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB;AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4gkhC-1iv8A:undetectable;4gkhK-1iv8A:0.0","4gkhC-1iv8A:16.69;4gkhK-1iv8A:16.69"],["4GKI_A_KANA301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.15A","4gkiA-1iv8A:undetectable","4gkiA-1iv8A:16.69"],["4GKI_C_KANC301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 228;ASP A 596;ASP A 443;GLU A 255","None;MLZ A 513 ( 4.9A);None;None","1.16A","4gkiC-1iv8A:undetectable","4gkiC-1iv8A:16.69"],["4M5M_A_DX4A401_0","2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"GLY A 579;LEU A 573;ASN A 437;PHE A 276","None","1.03A","4m5mA-1iv8A:0.2","4m5mA-1iv8A:13.70"],["4O0O_A_URFA303_1","RRNA N-GLYCOSIDASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"TYR A 415;ASN A 278;TYR A 279;ILE A 418","None","1.28A","4o0oA-1iv8A:undetectable","4o0oA-1iv8A:16.11"],["4OKW_A_198A1001_2","ANDROGEN RECEPTOR","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LEU A 163;LEU A 127;LEU A 174;ILE A 125","None","0.93A","4okwA-1iv8A:3.5","4okwA-1iv8A:15.37"],["4OTW_A_DB8A1101_2","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"LEU A 154;LEU A 100;ASN A 178","None;None;MLZ A 105 ( 4.3A)","0.64A","4otwA-1iv8A:undetectable","4otwA-1iv8A:18.95"],["4PTJ_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"ASP A 628;LYS A 632;LEU A 568","None","1.03A","4ptjA-1iv8A:0.0","4ptjA-1iv8A:10.97"],["4U9U_A_ACTA1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ARG A 430;GLY A 579;ALA A 578;GLY A 432","None","0.94A","4u9uA-1iv8A:2.1","4u9uA-1iv8A:15.71"],["4U9U_B_ACTB1502_0","NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT F","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ARG A 430;GLY A 579;ALA A 578;GLY A 432","None","0.85A","4u9uB-1iv8A:undetectable","4u9uB-1iv8A:15.71"],["4YSH_B_GLYB402_0","GLYCINE OXIDASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"GLU A 255;TYR A  50;ARG A   7;ARG A 226","None","1.49A","4yshB-1iv8A:0.8","4yshB-1iv8A:19.67"],["4YV5_A_SVRA205_1","BASIC PHOSPHOLIPASE A2 HOMOLOG 2","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LYS A 614;TYR A 637;LEU A 608;PHE A 605","None;MLZ A 638 ( 4.0A);None;None","1.08A","4yv5A-1iv8A:undetectable","4yv5A-1iv8A:10.36"],["4YV5_B_SVRB207_2","BASIC PHOSPHOLIPASE A2 HOMOLOG 2","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LYS A 614;TYR A 637;LEU A 608;PHE A 605","None;MLZ A 638 ( 4.0A);None;None","1.11A","4yv5B-1iv8A:0.0","4yv5B-1iv8A:10.36"],["5B1A_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.92A","5b1aA-1iv8A:0.0;5b1aJ-1iv8A:0.0","5b1aA-1iv8A:20.68;5b1aJ-1iv8A:5.63"],["5B3S_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.92A","5b3sA-1iv8A:0.0;5b3sJ-1iv8A:undetectable","5b3sA-1iv8A:20.68;5b3sJ-1iv8A:5.63"],["5B8I_C_FK5C201_1","SERINE\/THREONINE-PROTEIN PHOSPHATASE;PEPTIDYL-PROLYL CIS-TRANS ISOMERASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"SER A 458;PRO A 461;PHE A 460;GLU A 463","None;None;MLY A 558 ( 4.4A);MLY A 558 ( 3.0A)","1.19A","5b8iA-1iv8A:0.1","5b8iA-1iv8A:19.46"],["5CSY_B_ACRB601_1","4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC\/AMYLOPLASTIC","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ARG A 226;ASP A 228;GLU A 255;HIS A 442;ASP A 443","None","0.48A","5csyB-1iv8A:7.3","5csyB-1iv8A:22.55"],["5CSY_B_ACRB601_1","4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC\/AMYLOPLASTIC","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"ASP A 394;ASP A 228;GLU A 255;HIS A 442;ASP A 443","MLY A 390 ( 3.8A);None;None;None;None","0.84A","5csyB-1iv8A:7.3","5csyB-1iv8A:22.55"],["5G48_A_1FLA1375_1","DNA POLYMERASE III SUBUNIT BETA","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"LEU A 639;PRO A 714;ILE A 716;LEU A 642","MLZ A 638 ( 4.2A);None;None;MLZ A 638 ( 4.6A)","0.90A","5g48A-1iv8A:undetectable","5g48A-1iv8A:21.30"],["5IGY_A_ERYA403_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"TYR A 274;ASP A 228;ILE A 253;TYR A  35","None","1.49A","5igyA-1iv8A:2.5","5igyA-1iv8A:18.88"],["5Z84_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 125;PHE A 118;ARG A 192;THR A 198","None","1.18A","5z84N-1iv8A:0.0;5z84W-1iv8A:0.0","5z84N-1iv8A:20.68;5z84W-1iv8A:5.63"],["5ZCP_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.91A","5zcpA-1iv8A:0.0;5zcpJ-1iv8A:0.0","5zcpA-1iv8A:20.68;5zcpJ-1iv8A:5.63"],["5ZCQ_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ILE A 129;LEU A 181;TYR A 190;LEU A 104","None;None;None;MLZ A 105 ( 4.3A)","0.92A","5zcqA-1iv8A:0.0;5zcqJ-1iv8A:undetectable","5zcqA-1iv8A:20.68;5zcqJ-1iv8A:5.63"],["6AG0_A_ACRA610_0","ALPHA-AMYLASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",5,"TYR A  50;HIS A  90;ASP A 228;HIS A 442;ASP A 443","None","0.50A","6ag0A-1iv8A:20.8","6ag0A-1iv8A:7.36"],["6EXI_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"LEU A 689;ASN A 711;LEU A 664","None","0.69A","6exiA-1iv8A:undetectable","6exiA-1iv8A:7.97"],["6MN4_B_AM2B301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"HIS A 510;GLU A 517;ASP A 394;GLU A 393","None;MLY A 390 ( 3.7A);MLY A 390 ( 3.8A);None","1.14A","6mn4B-1iv8A:0.0","6mn4B-1iv8A:15.83"],["6MN4_C_AM2C301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"ASP A 596;GLU A 517;ASP A 394;GLU A 393","MLZ A 513 ( 4.9A);MLY A 390 ( 3.7A);MLY A 390 ( 3.8A);None","1.17A","6mn4C-1iv8A:undetectable","6mn4C-1iv8A:15.83"],["6MN4_C_AM2C301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"HIS A 510;GLU A 517;ASP A 394;GLU A 393","None;MLY A 390 ( 3.7A);MLY A 390 ( 3.8A);None","1.24A","6mn4C-1iv8A:undetectable","6mn4C-1iv8A:15.83"],["6MN4_D_AM2D301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",4,"HIS A 510;GLU A 517;ASP A 394;GLU A 393","None;MLY A 390 ( 3.7A);MLY A 390 ( 3.8A);None","1.19A","6mn4D-1iv8A:0.0","6mn4D-1iv8A:15.83"],["6NKN_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1iv8","MALTOOLIGOSYL TREHALOSE SYNTHASE","Sulfolobus acidocaldarius",3,"ARG A 430;PHE A 650;PHE A 276","None","0.81A","6nknC-1iv8A:0.0;6nknJ-1iv8A:0.0","6nknC-1iv8A:16.13;6nknJ-1iv8A:5.63"]]