SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ivl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IG3_A_VIBA502_1 (THIAMIN PYROPHOSPHOKINASE)	1ivl	IGG-KAPPA M29B FV (LIGHT CHAIN) (Mus musculus)	4 / 8	SER A 18 SER A 74 ASN A 76 ASP A 82	None	1.11A	1ig3A-1ivlA: undetectable 1ig3B-1ivlA: undetectable	1ig3A-1ivlA: 16.60 1ig3B-1ivlA: 16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IG3_B_VIBB501_1 (THIAMIN PYROPHOSPHOKINASE)	1ivl	IGG-KAPPA M29B FV (LIGHT CHAIN) (Mus musculus)	4 / 7	ASP A 82 SER A 18 SER A 74 ASN A 76	None	1.11A	1ig3A-1ivlA: undetectable 1ig3B-1ivlA: undetectable	1ig3A-1ivlA: 16.60 1ig3B-1ivlA: 16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_C_VIAC901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	1ivl	IGG-KAPPA M29B FV (LIGHT CHAIN) (Mus musculus)	4 / 7	TYR A 50 LEU A 4 GLN A 90 PHE A 96	None	1.11A	3jwqC-1ivlA: undetectable	3jwqC-1ivlA: 15.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IG3_A_VIBA502_1","THIAMIN PYROPHOSPHOKINASE;THIAMIN PYROPHOSPHOKINASE","1ivl","IGG-KAPPA M29B FV (LIGHT CHAIN)","Mus musculus",4,"SER A  18;SER A  74;ASN A  76;ASP A  82","None","1.11A","1ig3A-1ivlA:undetectable;1ig3B-1ivlA:undetectable","1ig3A-1ivlA:16.60;1ig3B-1ivlA:16.60"],["1IG3_B_VIBB501_1","THIAMIN PYROPHOSPHOKINASE;THIAMIN PYROPHOSPHOKINASE","1ivl","IGG-KAPPA M29B FV (LIGHT CHAIN)","Mus musculus",4,"ASP A  82;SER A  18;SER A  74;ASN A  76","None","1.11A","1ig3A-1ivlA:undetectable;1ig3B-1ivlA:undetectable","1ig3A-1ivlA:16.60;1ig3B-1ivlA:16.60"],["3JWQ_C_VIAC901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","1ivl","IGG-KAPPA M29B FV (LIGHT CHAIN)","Mus musculus",4,"TYR A  50;LEU A   4;GLN A  90;PHE A  96","None","1.11A","3jwqC-1ivlA:undetectable","3jwqC-1ivlA:15.71"]]