SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iw8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 8 LEU A  95
LEU A  98
LEU A 218
ALA A 221
LYS A 222
 None
 1.18A 1e7cA-1iw8A:
undetectable		 1e7cA-1iw8A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.32A 1p6kA-1iw8A:
0.0		 1p6kA-1iw8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.29A 1p6kB-1iw8A:
0.0		 1p6kB-1iw8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 12 LEU A 218
ALA A 110
ALA A 106
VAL A 160
LEU A  99
 None
 1.27A 1rbpA-1iw8A:
undetectable		 1rbpA-1iw8A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.28A 1rs6A-1iw8A:
0.0		 1rs6A-1iw8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.27A 1rs6B-1iw8A:
0.0		 1rs6B-1iw8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.21A 1rs7B-1iw8A:
0.0		 1rs7B-1iw8A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		6 / 12 HIS A 189
SER A 148
LEU A 179
GLY A 176
VAL A  75
ALA A  76
 SO4  A1001 (-4.5A)
SO4  A1001 (-3.6A)
None
None
None
None
 1.38A 1tsnA-1iw8A:
undetectable		 1tsnA-1iw8A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.31A 1zzqA-1iw8A:
0.0		 1zzqA-1iw8A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.32A 1zzqB-1iw8A:
0.0		 1zzqB-1iw8A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.29A 1zzuA-1iw8A:
0.0		 1zzuA-1iw8A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.32A 1zzuB-1iw8A:
undetectable		 1zzuB-1iw8A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.18A 2eimJ-1iw8A:
0.0		 2eimJ-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.19A 2eimW-1iw8A:
0.0		 2eimW-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 12 GLY A 176
ALA A 156
THR A 157
ALA A 197
HIS A 150
 None
 1.07A 2gluA-1iw8A:
undetectable		 2gluA-1iw8A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 12 PHE A 214
ALA A 213
ALA A 162
ALA A 158
MET A 102
 None
 1.19A 2x2nA-1iw8A:
undetectable		 2x2nA-1iw8A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 12 PHE A 214
ALA A 213
ALA A 162
ALA A 158
MET A 102
 None
 1.19A 2x2nB-1iw8A:
0.0		 2x2nB-1iw8A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.36A 3ag1J-1iw8A:
0.0		 3ag1J-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.19A 3ag2J-1iw8A:
0.0		 3ag2J-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.18A 3ag4J-1iw8A:
0.0		 3ag4J-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 7 ASP A  45
GLN A  46
TYR A  49
GLN A  51
 None
 1.23A 3l2vA-1iw8A:
undetectable		 3l2vA-1iw8A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.20A 3n62A-1iw8A:
0.0		 3n62A-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.25A 3n62B-1iw8A:
0.0		 3n62B-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.24A 3n66B-1iw8A:
0.0		 3n66B-1iw8A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 9 LEU A  55
ALA A  64
ASP A  67
VAL A 184
ILE A 185
 None
 1.21A 3wsjA-1iw8A:
undetectable		 3wsjA-1iw8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 7 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.29A 4kcnB-1iw8A:
0.0		 4kcnB-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		3 / 3 HIS A 117
VAL A 200
LEU A  31
 None
 0.71A 4m2vA-1iw8A:
undetectable		 4m2vA-1iw8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 12 ILE A  87
ALA A  78
VAL A 205
LEU A  99
LEU A 173
 None
 1.28A 4qynA-1iw8A:
undetectable		 4qynA-1iw8A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		5 / 12 GLY A 154
THR A 157
VAL A 205
ALA A 197
ALA A 110
 None
 0.90A 5kpcA-1iw8A:
undetectable		 5kpcA-1iw8A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.28A 5vunA-1iw8A:
0.0		 5vunA-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.33A 5vunB-1iw8A:
0.0		 5vunB-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.32A 5vuoB-1iw8A:
0.0		 5vuoB-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.41A 5w97J-1iw8A:
0.0		 5w97J-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.26A 5wauJ-1iw8A:
0.0		 5wauJ-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.33A 5x19J-1iw8A:
0.0		 5x19J-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.35A 5x1bJ-1iw8A:
0.2		 5x1bJ-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.34A 5x1bW-1iw8A:
0.0		 5x1bW-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.35A 5x1fW-1iw8A:
0.0		 5x1fW-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.20A 5z86J-1iw8A:
0.0		 5z86J-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.32A 6auuB-1iw8A:
undetectable		 6auuB-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 8 ALA A 196
LEU A  31
ALA A 114
LYS A 115
 None
None
None
SO4  A1001 (-2.5A)
 0.83A 6mdqA-1iw8A:
2.0		 6mdqA-1iw8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.36A 6nknJ-1iw8A:
0.0		 6nknJ-1iw8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iw8 ACID PHOSPHATASE
(Shimwellia
blattae) 		4 / 5 TYR A  18
MET A 102
THR A 100
LEU A  99
 None
 1.31A 6nknW-1iw8A:
0.0		 6nknW-1iw8A:
17.37