SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iwa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 8 LEU A 291
THR A 243
VAL A 242
ALA A 276
 None
 0.93A 1fiqC-1iwaA:
undetectable		 1fiqC-1iwaA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 7 LEU A 400
MET A 266
TYR A 239
LEU A 197
 None
 1.02A 1kt3A-1iwaA:
undetectable		 1kt3A-1iwaA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 1.00A 1ra2A-1iwaA:
undetectable		 1ra2A-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 8 ALA A 417
ILE A 413
ILE A 407
GLY A 405
PRO A 410
 None
 1.49A 1sh9A-1iwaA:
undetectable		 1sh9A-1iwaA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 8 ARG A 421
ALA A 417
GLU A 234
VAL A 200
 None
 0.73A 2bxgA-1iwaA:
undetectable		 2bxgA-1iwaA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 1.06A 2drcB-1iwaA:
undetectable		 2drcB-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		3 / 3 ASN A 207
ILE A 265
MET A 280
 None
 0.83A 2h42C-1iwaA:
0.0		 2h42C-1iwaA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 HIS A 292
ILE A 382
LEU A 400
GLY A 171
ALA A 378
 None
 0.97A 2oc8A-1iwaA:
undetectable		 2oc8A-1iwaA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 6 GLN A 414
ALA A 224
ALA A 228
THR A 232
 None
 1.08A 2xfhA-1iwaA:
0.0		 2xfhA-1iwaA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		4 / 7 GLN B  12
ILE B  10
ASP B  47
SER B 147
 None
 1.19A 2xytI-1iwaB:
0.0		 2xytI-1iwaB:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 8 LEU A 291
THR A 243
VAL A 242
ALA A 276
 None
 0.89A 3ax9A-1iwaA:
undetectable		 3ax9A-1iwaA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 8 GLY A 395
VAL A 398
LEU A 400
PRO A 168
 None
 0.98A 3bgdB-1iwaA:
undetectable		 3bgdB-1iwaA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 1.06A 3drcB-1iwaA:
undetectable		 3drcB-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		5 / 12 ILE B  40
GLY B  41
VAL B 101
LEU B  72
VAL B  77
 None
 0.99A 3fpjA-1iwaB:
undetectable		 3fpjA-1iwaB:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		5 / 12 SER B 144
GLU B 123
PRO B 124
ASN B  64
GLU B  43
 None
 1.41A 3jb2A-1iwaB:
0.0		 3jb2A-1iwaB:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 LEU A 145
PHE A 148
PHE A 108
LEU A 116
LEU A  37
 None
 1.34A 3tbgA-1iwaA:
0.0		 3tbgA-1iwaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 LEU A 145
PHE A 148
PHE A 108
LEU A 116
LEU A  37
 None
 1.32A 3tbgC-1iwaA:
0.0		 3tbgC-1iwaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		4 / 7 ASN B  64
ILE B  48
MET B   8
GLN B  12
 None
 1.26A 3tvxB-1iwaB:
undetectable		 3tvxB-1iwaB:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 8 LEU A 291
THR A 243
VAL A 242
ALA A 276
 None
 0.89A 3uniB-1iwaA:
0.0		 3uniB-1iwaA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 6 GLY A 337
ASP A 476
ASN A 310
GLU A 136
 None
 0.99A 3vywC-1iwaA:
undetectable		 3vywC-1iwaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 PHE A 108
LEU A 105
ILE A 101
ARG A 139
GLY A  59
 None
 1.12A 4dm8B-1iwaA:
0.0		 4dm8B-1iwaA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 10 ILE A 444
ALA A 430
GLU A 425
GLY A 395
HIS A 388
 None
 1.50A 4e47D-1iwaA:
0.0		 4e47D-1iwaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 1.01A 4ej1A-1iwaA:
undetectable		 4ej1A-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 11 ILE A 444
ALA A 430
GLU A 425
GLY A 395
HIS A 388
 None
 1.39A 4j83A-1iwaA:
0.0		 4j83A-1iwaA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 11 ILE A 444
ALA A 430
GLU A 425
GLY A 395
HIS A 388
 None
 1.29A 4jdsA-1iwaA:
undetectable		 4jdsA-1iwaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 11 ILE A 444
ALA A 430
GLU A 425
GLY A 395
HIS A 388
 None
 1.30A 4jdsB-1iwaA:
undetectable		 4jdsB-1iwaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 11 ILE A 444
ALA A 430
GLU A 425
GLY A 395
HIS A 388
 None
 1.43A 4jdsD-1iwaA:
0.0		 4jdsD-1iwaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 11 ILE A 444
ALA A 430
GLU A 425
GLY A 395
HIS A 388
 None
 1.38A 4jlgB-1iwaA:
0.0		 4jlgB-1iwaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.99A 4kjjA-1iwaA:
undetectable		 4kjjA-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 1.01A 4kjkA-1iwaA:
undetectable		 4kjkA-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.98A 4kjlA-1iwaA:
undetectable		 4kjlA-1iwaA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.99A 4nx6A-1iwaA:
undetectable		 4nx6A-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.98A 4nx7A-1iwaA:
undetectable		 4nx7A-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 1.00A 4p3qA-1iwaA:
undetectable		 4p3qA-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		5 / 12 GLY B  41
VAL B 101
ILE B  42
PHE B  85
LEU B  84
 None
 0.94A 4pd4C-1iwaB:
undetectable		 4pd4C-1iwaB:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.99A 4pstA-1iwaA:
undetectable		 4pstA-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.99A 4pthA-1iwaA:
undetectable		 4pthA-1iwaA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 6 ALA A 378
ILE A 428
GLY A 395
ILE A 382
 None
 0.76A 4r21A-1iwaA:
undetectable		 4r21A-1iwaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.98A 4x5gB-1iwaA:
undetectable		 4x5gB-1iwaA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		4 / 6 LEU B  21
ASP B  23
GLU B  24
ILE B 113
 None
 1.10A 4xi3C-1iwaB:
undetectable		 4xi3C-1iwaB:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		3 / 5 GLY B 103
GLY B  41
GLU B  43
 None
 0.43A 4z2eA-1iwaB:
undetectable
4z2eD-1iwaB:
undetectable		 4z2eA-1iwaB:
16.11
4z2eD-1iwaB:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E SMALL SUBUNIT
(Galdieria
partita) 		4 / 7 PRO B  80
VAL B  83
ILE B  87
ILE B  34
 None
 0.78A 5bmvC-1iwaB:
undetectable		 5bmvC-1iwaB:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		4 / 5 SER A  61
MET A 309
LEU A 135
PHE A  40
 None
 1.28A 5evyX-1iwaA:
0.0		 5evyX-1iwaA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		3 / 3 ILE A 264
MET A 250
ASP A 202
 None
 0.79A 5h2uA-1iwaA:
undetectable		 5h2uA-1iwaA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		5 / 12 ALA A 252
ILE A 267
LEU A 291
ILE A 265
TYR A 218
 None
 0.98A 5z6kA-1iwaA:
undetectable		 5z6kA-1iwaA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		3 / 3 ASP A 198
ARG A 421
ASP A 163
 None
 0.86A 5zvgA-1iwaA:
undetectable		 5zvgA-1iwaA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1iwa RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Galdieria
partita) 		3 / 3 ARG A 159
ARG A 431
ARG A 167
 None
 0.98A 6bplA-1iwaA:
0.4
6bplB-1iwaA:
0.6		 6bplA-1iwaA:
10.37
6bplB-1iwaA:
10.37