SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ixx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A  40
TRP A  23
 None
 1.20A 1c4dC-1ixxA:
undetectable
1c4dD-1ixxA:
undetectable		 1c4dC-1ixxA:
11.49
1c4dD-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.33A 1c4dC-1ixxA:
undetectable
1c4dD-1ixxA:
undetectable		 1c4dC-1ixxA:
11.49
1c4dD-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.19A 2xdcA-1ixxA:
undetectable
2xdcB-1ixxA:
undetectable		 2xdcA-1ixxA:
11.49
2xdcB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  67
TRP A  23
 None
 1.45A 2xdcA-1ixxA:
undetectable
2xdcB-1ixxA:
undetectable		 2xdcA-1ixxA:
11.49
2xdcB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  23
VAL A 126
TRP A  67
 None
 1.45A 2xdcA-1ixxA:
undetectable
2xdcB-1ixxA:
undetectable		 2xdcA-1ixxA:
11.49
2xdcB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.20A 2xdcA-1ixxA:
undetectable
2xdcB-1ixxA:
undetectable		 2xdcA-1ixxA:
11.49
2xdcB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.18A 2xdcC-1ixxA:
undetectable
2xdcD-1ixxA:
undetectable		 2xdcC-1ixxA:
11.49
2xdcD-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.08A 2xdcC-1ixxA:
undetectable
2xdcD-1ixxA:
undetectable		 2xdcC-1ixxA:
11.49
2xdcD-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.11A 2xdcE-1ixxA:
undetectable
2xdcF-1ixxA:
undetectable		 2xdcE-1ixxA:
11.49
2xdcF-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.18A 2y5mA-1ixxA:
undetectable
2y5mB-1ixxA:
undetectable		 2y5mA-1ixxA:
11.49
2y5mB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  67
TRP A  23
 None
 1.44A 2y5mA-1ixxA:
undetectable
2y5mB-1ixxA:
undetectable		 2y5mA-1ixxA:
11.49
2y5mB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.08A 2y5mE-1ixxA:
undetectable
2y5mF-1ixxA:
undetectable		 2y5mE-1ixxA:
11.49
2y5mF-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.17A 2y6nA-1ixxA:
undetectable
2y6nB-1ixxA:
undetectable		 2y6nA-1ixxA:
11.49
2y6nB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  67
TRP A  23
 None
 1.45A 2y6nA-1ixxA:
undetectable
2y6nB-1ixxA:
undetectable		 2y6nA-1ixxA:
11.49
2y6nB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  23
VAL A 126
TRP A  67
 None
 1.44A 2y6nA-1ixxA:
undetectable
2y6nB-1ixxA:
undetectable		 2y6nA-1ixxA:
11.49
2y6nB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.19A 2y6nA-1ixxA:
undetectable
2y6nB-1ixxA:
undetectable		 2y6nA-1ixxA:
11.49
2y6nB-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.06A 2y6nC-1ixxA:
undetectable
2y6nD-1ixxA:
undetectable		 2y6nC-1ixxA:
11.49
2y6nD-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.06A 2y6nE-1ixxA:
undetectable
2y6nF-1ixxA:
undetectable		 2y6nE-1ixxA:
11.49
2y6nF-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.14A 3zq8A-1ixxA:
undetectable
3zq8B-1ixxA:
undetectable		 3zq8A-1ixxA:
11.49
3zq8B-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		3 / 3 TRP A  67
VAL A  40
TRP A  23
 None
 0.96A 3zq8C-1ixxA:
undetectable
3zq8D-1ixxA:
undetectable		 3zq8C-1ixxA:
11.49
3zq8D-1ixxA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		5 / 12 ASN A  58
MET A  59
VAL A  40
LYS A  15
ILE A  66
 None
 1.10A 4x1kD-1ixxA:
undetectable		 4x1kD-1ixxA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		5 / 12 ASN A  58
MET A  59
VAL A  40
LYS A  15
ILE A  66
 None
 1.13A 4x1yB-1ixxA:
undetectable		 4x1yB-1ixxA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		5 / 12 ASN A  58
MET A  59
VAL A  40
LYS A  15
ILE A  66
 None
 1.04A 4x1yD-1ixxA:
undetectable		 4x1yD-1ixxA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		5 / 11 ASN A  58
MET A  59
VAL A  40
LYS A  15
ILE A  66
 None
 1.13A 4x20D-1ixxA:
undetectable		 4x20D-1ixxA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		5 / 12 GLU A  47
SER A  44
GLN A  73
GLY A  69
LEU A  70
 CA  A 130 ( 2.9A)
None
None
None
None
 1.40A 5m50B-1ixxA:
undetectable		 5m50B-1ixxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 1ixx COAGULATION FACTORS
IX/X-BINDING PROTEIN
(Protobothrops
flavoviridis) 		4 / 5 HIS A  38
GLU A  43
LEU A  54
VAL A  51
 None
CA  A 130 ( 3.5A)
None
None
 1.20A 6bc9A-1ixxA:
undetectable		 6bc9A-1ixxA:
19.55