SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iyn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 8 HIS A 163
GLY A 166
LEU A 221
ASP A 224
 HEM  A 296 (-3.4A)
HEM  A 296 (-3.2A)
HEM  A 296 ( 4.9A)
None
 0.37A 1aegA-1iynA:
32.9		 1aegA-1iynA:
32.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		3 / 3 LYS A  78
ASP A  35
CYH A 124
 None
NA  A 298 (-3.1A)
None
 1.49A 2br4F-1iynA:
undetectable		 2br4F-1iynA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 6 TYR A 251
ALA A 252
ALA A  98
THR A  99
 None
 0.87A 3b6hA-1iynA:
0.8		 3b6hA-1iynA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		5 / 12 SER A  97
HIS A 255
TYR A 251
ALA A 100
GLY A 106
 None
 1.12A 3f8wC-1iynA:
undetectable		 3f8wC-1iynA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		5 / 12 HIS A 255
ILE A 101
GLY A 105
ALA A 104
LEU A 200
 None
 1.25A 3n8xA-1iynA:
0.0		 3n8xA-1iynA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		5 / 9 ASP A 209
SER A 205
THR A 164
ASP A 215
ASP A 217
 None
None
NA  A 297 (-3.2A)
None
None
 1.32A 3sfuA-1iynA:
undetectable		 3sfuA-1iynA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		5 / 12 LEU A 159
GLY A  50
ALA A  52
ASN A  53
LEU A 151
 HEM  A 296 (-4.0A)
None
None
NA  A 298 (-2.9A)
None
 0.94A 4dc3A-1iynA:
undetectable		 4dc3A-1iynA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 7 ASP A 224
THR A 223
SER A 160
HIS A 163
 None
HEM  A 296 (-3.5A)
HEM  A 296 ( 3.7A)
HEM  A 296 (-3.4A)
 1.22A 4o4dA-1iynA:
0.0		 4o4dA-1iynA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		3 / 3 ARG A 129
PRO A 125
ASN A  53
 None
None
NA  A 298 (-2.9A)
 0.88A 5jwaA-1iynA:
undetectable
5jwaH-1iynA:
undetectable		 5jwaA-1iynA:
20.55
5jwaH-1iynA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_A_NIZA805_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 5 ARG A  30
TRP A  33
HIS A  34
ALA A  66
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
None
 0.38A 5syiA-1iynA:
28.3		 5syiA-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_B_NIZB806_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 5 ARG A  30
TRP A  33
HIS A  34
SER A 168
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
HEM  A 296 (-2.9A)
 1.37A 5syiB-1iynA:
9.3		 5syiB-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_B_NIZB806_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 5 ARG A  30
TRP A  33
HIS A  34
SER A 173
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
HEM  A 296 (-3.3A)
 0.39A 5syiB-1iynA:
9.3		 5syiB-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 6 ARG A  30
TRP A  33
HIS A  34
SER A 168
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
HEM  A 296 (-2.9A)
 1.37A 5syjA-1iynA:
10.2		 5syjA-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 6 ARG A  30
TRP A  33
HIS A  34
SER A 173
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
HEM  A 296 (-3.3A)
 0.39A 5syjA-1iynA:
10.2		 5syjA-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 6 ARG A  30
TRP A  33
HIS A  34
SER A 168
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
HEM  A 296 (-2.9A)
 1.36A 5syjB-1iynA:
9.5		 5syjB-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 6 ARG A  30
TRP A  33
HIS A  34
SER A 173
 HEM  A 296 (-3.9A)
HEM  A 296 (-3.7A)
None
HEM  A 296 (-3.3A)
 0.41A 5syjB-1iynA:
9.5		 5syjB-1iynA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		4 / 8 THR A 164
TYR A 206
ARG A 167
TRP A 195
 NA  A 297 (-3.2A)
None
None
None
 1.39A 5tzoA-1iynA:
undetectable		 5tzoA-1iynA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1iyn CHLOROPLASTIC
ASCORBATE PEROXIDASE
(Nicotiana
tabacum) 		5 / 12 ALA A 263
GLY A  51
THR A  38
GLY A  50
PHE A 265
 None
NA  A 298 (-4.3A)
NA  A 298 ( 4.8A)
None
None
 1.14A 5ybbA-1iynA:
undetectable		 5ybbA-1iynA:
20.98