SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 1iz6 INITIATION FACTOR 5A
(Pyrococcus
horikoshii) 		4 / 5 LYS A  60
PRO A  61
SER A  40
SER A  10
 None
 1.08A 3ijxH-1iz6A:
undetectable		 3ijxH-1iz6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 1iz6 INITIATION FACTOR 5A
(Pyrococcus
horikoshii) 		4 / 5 LYS A  60
PRO A  61
SER A  40
SER A  10
 None
 1.15A 3iluH-1iz6A:
0.0		 3iluH-1iz6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1iz6 INITIATION FACTOR 5A
(Pyrococcus
horikoshii) 		3 / 3 GLN A  77
THR A  75
ASN A 118
 None
 0.57A 3v4tE-1iz6A:
0.0		 3v4tE-1iz6A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1iz6 INITIATION FACTOR 5A
(Pyrococcus
horikoshii) 		5 / 8 VAL A   9
ILE A  27
LEU A  12
ILE A  18
ILE A  20
 None
 1.05A 5numA-1iz6A:
undetectable		 5numA-1iz6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1iz6 INITIATION FACTOR 5A
(Pyrococcus
horikoshii) 		5 / 8 VAL A   9
ILE A  45
LEU A  12
ILE A  18
ILE A  20
 None
 1.29A 5numA-1iz6A:
undetectable		 5numA-1iz6A:
23.19