SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 LEU A 644
LEU A 401
LEU A 681
LEU A 679
 None
 0.91A 1errA-1j0nA:
0.4		 1errA-1j0nA:
14.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		6 / 7 ASN A 146
TRP A 148
TYR A 255
ARG A 309
ARG A 313
ASN A 424
 None
CEG  A 780 (-3.6A)
CEG  A 780 (-4.4A)
CEG  A 780 (-3.6A)
CEG  A 780 (-2.9A)
None
 0.74A 1f9gA-1j0nA:
47.8		 1f9gA-1j0nA:
30.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 GLY A 322
ASP A 355
GLY A 362
THR A 368
 None
 1.04A 1hxbB-1j0nA:
undetectable		 1hxbB-1j0nA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 ARG A 101
VAL A 163
TRP A  36
 None
 1.11A 1qw6A-1j0nA:
0.0		 1qw6A-1j0nA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 ARG A 101
VAL A 163
TRP A  36
 None
 1.09A 1qwcA-1j0nA:
0.0		 1qwcA-1j0nA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 ARG A 101
VAL A 163
TRP A  36
 None
 1.08A 1vagA-1j0nA:
0.0		 1vagA-1j0nA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 ARG A 101
VAL A 163
TRP A  36
 None
 1.11A 1zviA-1j0nA:
0.0		 1zviA-1j0nA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 LEU A 131
GLU A  98
SER A 157
ASP A  70
ALA A  83
 None
CEG  A 780 ( 4.9A)
None
None
None
 1.13A 2bm9A-1j0nA:
undetectable		 2bm9A-1j0nA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 LEU A 131
GLU A  98
SER A 157
ASP A  70
ALA A  83
 None
CEG  A 780 ( 4.9A)
None
None
None
 1.29A 2bm9B-1j0nA:
undetectable		 2bm9B-1j0nA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 HIS A 323
ALA A 372
ILE A 375
VAL A 326
ILE A 289
 None
 1.15A 2h42B-1j0nA:
undetectable		 2h42B-1j0nA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 LEU A 734
LEU A 487
PHE A 774
 None
 0.72A 2pgrA-1j0nA:
undetectable		 2pgrA-1j0nA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 8 ASN A 685
GLY A 483
ILE A 518
VAL A 675
 None
 0.79A 2yoeB-1j0nA:
3.2
2yoeC-1j0nA:
2.2		 2yoeB-1j0nA:
17.22
2yoeC-1j0nA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_1
(HYPOTHETICAL PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 GLU A 122
ASP A 129
ASP A 168
TYR A 177
 None
 1.27A 2yvlA-1j0nA:
0.0		 2yvlA-1j0nA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 ALA A 458
ILE A 609
PHE A 249
ARG A 398
TYR A 452
 None
 1.18A 3cl9A-1j0nA:
undetectable		 3cl9A-1j0nA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 LEU A 575
VAL A 573
LEU A 595
MET A 627
TYR A 452
 None
 1.48A 3dzyD-1j0nA:
0.0		 3dzyD-1j0nA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 ILE A 525
GLY A 522
LEU A 521
VAL A 537
ILE A 629
 None
 0.88A 3em6B-1j0nA:
undetectable		 3em6B-1j0nA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		6 / 12 GLY A  42
VAL A 110
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 1.17A 3mteB-1j0nA:
undetectable		 3mteB-1j0nA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		6 / 12 GLY A  43
VAL A 110
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 1.42A 3mteB-1j0nA:
undetectable		 3mteB-1j0nA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 GLY A  42
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 1.05A 3p2kA-1j0nA:
undetectable		 3p2kA-1j0nA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 GLY A  43
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 0.86A 3p2kA-1j0nA:
undetectable		 3p2kA-1j0nA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 GLY A  42
VAL A 110
ALA A 104
LEU A  39
LEU A 164
 None
 1.01A 3p2kB-1j0nA:
undetectable		 3p2kB-1j0nA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 GLY A  43
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 0.90A 3p2kC-1j0nA:
undetectable		 3p2kC-1j0nA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		6 / 12 GLY A  42
VAL A 110
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 1.13A 3p2kD-1j0nA:
undetectable		 3p2kD-1j0nA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		6 / 12 GLY A  43
VAL A 110
ALA A 107
ALA A 104
LEU A  39
LEU A 164
 None
 1.45A 3p2kD-1j0nA:
undetectable		 3p2kD-1j0nA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 THR A 615
ASN A 610
GLY A 604
THR A 603
 None
 0.78A 3tajA-1j0nA:
undetectable		 3tajA-1j0nA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ALA A 386
PRO A 387
TYR A 298
ALA A 407
 None
 1.10A 3twpA-1j0nA:
2.1		 3twpA-1j0nA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ALA A 386
PRO A 387
TYR A 298
ALA A 407
 None
 1.12A 3twpB-1j0nA:
undetectable		 3twpB-1j0nA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ALA A 386
PRO A 387
TYR A 298
ALA A 407
 None
 1.13A 3twpC-1j0nA:
undetectable		 3twpC-1j0nA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 5 ALA A 386
PRO A 387
TYR A 298
ALA A 407
 None
 1.10A 3twpD-1j0nA:
1.7		 3twpD-1j0nA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 5 HIS A 771
SER A 718
SER A 486
VAL A 485
 None
 1.24A 4a99D-1j0nA:
undetectable		 4a99D-1j0nA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 GLY A 205
ARG A 101
ILE A 202
LEU A 270
 None
 1.08A 4ac9C-1j0nA:
undetectable		 4ac9C-1j0nA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 GLY A 205
ARG A 101
ILE A 202
LEU A 270
 None
 1.09A 4acaC-1j0nA:
undetectable		 4acaC-1j0nA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 GLY A 205
ARG A 101
ILE A 202
LEU A 270
 None
 1.05A 4acbC-1j0nA:
undetectable		 4acbC-1j0nA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 TYR A 448
TYR A 452
ASN A 539
TYR A 587
 None
 1.26A 4f8yC-1j0nA:
undetectable
4f8yD-1j0nA:
undetectable		 4f8yC-1j0nA:
12.87
4f8yD-1j0nA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 ILE A 533
TYR A 432
TYR A 503
TYR A 500
 None
 1.24A 4g10A-1j0nA:
4.7		 4g10A-1j0nA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.33A 4jksA-1j0nA:
0.0		 4jksA-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.34A 4jksB-1j0nA:
undetectable		 4jksB-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.33A 4jkuA-1j0nA:
0.0		 4jkuA-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.35A 4k8cB-1j0nA:
0.0		 4k8cB-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.35A 4k8kA-1j0nA:
0.0		 4k8kA-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.34A 4kalA-1j0nA:
0.0		 4kalA-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.33A 4kalB-1j0nA:
0.0		 4kalB-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.34A 4lcaA-1j0nA:
0.0		 4lcaA-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 4 SER A 494
LEU A 681
TYR A 390
PRO A 722
 None
 1.32A 4lcaB-1j0nA:
undetectable		 4lcaB-1j0nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 ILE A 202
ALA A 220
ARG A  33
THR A 185
ILE A 181
 None
 1.07A 4m6kA-1j0nA:
undetectable		 4m6kA-1j0nA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 TYR A 390
THR A 248
THR A 476
MET A 303
 None
 1.14A 4mbsA-1j0nA:
0.0		 4mbsA-1j0nA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 VAL A 466
ALA A 467
TYR A 500
GLY A 469
THR A 464
 None
 1.13A 4mm4A-1j0nA:
0.1		 4mm4A-1j0nA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 VAL A 466
ALA A 467
TYR A 500
GLY A 469
THR A 464
 None
 1.15A 4mm4B-1j0nA:
0.0		 4mm4B-1j0nA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 11 SER A 704
SER A 674
GLU A 517
TYR A 390
GLY A 492
 None
None
CA  A 779 (-2.3A)
None
None
 1.31A 4qb9F-1j0nA:
0.0		 4qb9F-1j0nA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 ASP A  63
ALA A  61
THR A 102
TYR A  67
 None
 1.43A 4w5rA-1j0nA:
0.0		 4w5rA-1j0nA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 9 GLY A 194
ILE A 202
MET A 156
VAL A 259
THR A 262
 None
 1.10A 4x3mA-1j0nA:
undetectable		 4x3mA-1j0nA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 9 GLY A 194
ILE A 202
MET A 156
VAL A 259
THR A 262
 None
 1.10A 4x3mB-1j0nA:
undetectable		 4x3mB-1j0nA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 VAL A 209
ILE A 210
LEU A 105
LEU A 164
 None
 0.80A 4xo7A-1j0nA:
undetectable		 4xo7A-1j0nA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB402_0
(GLYCINE OXIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 5 GLU A 421
TYR A 255
ARG A 313
ARG A 309
 None
CEG  A 780 (-4.4A)
CEG  A 780 (-2.9A)
CEG  A 780 (-3.6A)
 1.30A 4yshB-1j0nA:
0.0		 4yshB-1j0nA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 5 VAL A 563
TYR A 452
ILE A 311
THR A 464
 None
 1.25A 4ze1A-1j0nA:
0.0		 4ze1A-1j0nA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ALA A 493
ASP A 695
GLY A 680
GLU A 709
 None
 0.99A 5bs8A-1j0nA:
undetectable
5bs8B-1j0nA:
undetectable
5bs8C-1j0nA:
undetectable		 5bs8A-1j0nA:
21.34
5bs8B-1j0nA:
15.69
5bs8C-1j0nA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ALA A 493
ASP A 695
GLY A 680
GLU A 709
 None
 0.97A 5btdA-1j0nA:
0.0
5btdB-1j0nA:
undetectable
5btdC-1j0nA:
0.0		 5btdA-1j0nA:
21.34
5btdB-1j0nA:
15.69
5btdC-1j0nA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ALA A 493
ASP A 695
GLY A 680
GLU A 709
 None
 0.97A 5btdA-1j0nA:
undetectable
5btdC-1j0nA:
0.0
5btdD-1j0nA:
undetectable		 5btdA-1j0nA:
21.34
5btdC-1j0nA:
21.34
5btdD-1j0nA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 8 THR A 193
GLY A 234
HIS A 246
THR A 247
 None
 0.95A 5eevL-1j0nA:
0.0
5eevV-1j0nA:
0.0		 5eevL-1j0nA:
7.39
5eevV-1j0nA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 8 THR A 193
GLY A 234
HIS A 246
THR A 247
 None
 0.95A 5eewL-1j0nA:
0.0
5eewV-1j0nA:
0.0		 5eewL-1j0nA:
7.39
5eewV-1j0nA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 GLU A 677
ILE A 629
GLY A 463
THR A 438
LEU A 644
 CA  A 779 (-3.4A)
None
None
None
None
 1.37A 5esgA-1j0nA:
undetectable		 5esgA-1j0nA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 ARG A 101
VAL A 163
TRP A  36
 None
 1.11A 5fvoA-1j0nA:
0.0		 5fvoA-1j0nA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 ASN A 504
SER A 506
SER A 499
 None
 0.72A 5gsnA-1j0nA:
0.0		 5gsnA-1j0nA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 ILE A 325
GLY A 324
LEU A 224
PHE A 228
 None
 0.85A 5hieB-1j0nA:
undetectable		 5hieB-1j0nA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 5 LEU A 128
TYR A 132
LEU A 158
TYR A  97
 None
 1.41A 5ki6A-1j0nA:
0.0		 5ki6A-1j0nA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 9 LEU A 595
ILE A 525
GLY A 522
VAL A 537
ILE A 629
 None
 1.10A 5kr2D-1j0nA:
undetectable		 5kr2D-1j0nA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.34A 5x7pA-1j0nA:
5.3		 5x7pA-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.32A 5x7pB-1j0nA:
5.2		 5x7pB-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.32A 5x7qA-1j0nA:
3.8		 5x7qA-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.31A 5x7qB-1j0nA:
6.2		 5x7qB-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.33A 5x7rA-1j0nA:
3.6		 5x7rA-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 6 TRP A 199
SER A 258
GLU A 310
TYR A 255
 None
CEG  A 780 ( 4.7A)
CEG  A 780 ( 4.3A)
CEG  A 780 (-4.4A)
 1.30A 5x7rB-1j0nA:
5.8		 5x7rB-1j0nA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 TYR A 587
PRO A 646
GLY A 586
ASN A 548
ASP A 538
 None
 1.26A 5yn6A-1j0nA:
0.0		 5yn6A-1j0nA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 TYR A 587
PRO A 646
GLY A 586
ASN A 548
ASP A 538
 None
 1.25A 5ynmA-1j0nA:
undetectable		 5ynmA-1j0nA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		5 / 12 ALA A 106
ALA A 107
LEU A  60
ALA A  61
LEU A 165
 None
 1.22A 6a5zD-1j0nA:
undetectable		 6a5zD-1j0nA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		3 / 3 SER A 720
SER A 704
ALA A 399
 None
 0.58A 6dwnC-1j0nA:
0.0		 6dwnC-1j0nA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 5 GLY A 483
LEU A 412
TYR A 390
GLN A 392
 None
 1.30A 6ji6A-1j0nA:
4.5		 6ji6A-1j0nA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 TRP A 453
THR A 433
ARG A 602
ASP A 457
 None
 1.28A 6mn4E-1j0nA:
0.0		 6mn4E-1j0nA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1j0n XANTHAN LYASE
(Bacillus
sp.
GL1) 		4 / 7 TRP A 550
THR A 597
ARG A 540
ASP A 538
 None
 1.21A 6mn4E-1j0nA:
0.0		 6mn4E-1j0nA:
16.40