SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1AQ7_B_AG2B4_1 (TRYPSIN AERUGINOSIN 98-B)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 8	HIS T 57 ASP T 189 SER T 195 VAL T 213 GLY T 216 GLY T 226	SO4 T 600 (-3.8A) ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.46A	1aq7A-1j17T: 42.9	1aq7A-1j17T: 71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1BCU_H_PRLH280_0 (ALPHA-THROMBIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	7 / 9	ASP T 189 ALA T 190 SER T 195 VAL T 213 TRP T 215 GLY T 216 GLY T 226	ZEN T 1 ( 3.8A) ZEN T 1 (-3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.32A	1bcuH-1j17T: 18.7	1bcuH-1j17T: 37.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DWC_H_MITH1_1 (ALPHA-THROMBIN (LARGE SUBUNIT))	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 9	HIS T 57 ASP T 189 SER T 195 TRP T 215 GLY T 226	SO4 T 600 (-3.8A) ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A)	0.37A	1dwcH-1j17T: 34.3	1dwcH-1j17T: 37.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_A_IBPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 9	VAL T 52 LEU T 68 ILE T 63 ALA T 85 SER T 109 LEU T 108	None	1.16A	1eqgA-1j17T: undetectable	1eqgA-1j17T: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 11	VAL T 52 LEU T 68 ILE T 63 ALA T 85 SER T 109 LEU T 108	None	1.16A	1eqgB-1j17T: undetectable	1eqgB-1j17T: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_A_FLPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 12	VAL T 52 LEU T 68 ILE T 63 ALA T 85 SER T 109 LEU T 108	None	1.17A	1eqhA-1j17T: undetectable	1eqhA-1j17T: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_B_FLPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 12	VAL T 52 LEU T 68 ILE T 63 ALA T 85 SER T 109 LEU T 108	None	1.16A	1eqhB-1j17T: undetectable	1eqhB-1j17T: 16.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ETR_H_MITH1_1 (EPSILON-THROMBIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	7 / 12	HIS T 57 ASP T 189 SER T 195 VAL T 213 TRP T 215 GLY T 216 GLY T 226	SO4 T 600 (-3.8A) ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.49A	1etrH-1j17T: 34.4	1etrH-1j17T: 38.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1F5L_A_AMRA301_1 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 8	ASP T 189 GLN T 192 SER T 195 VAL T 213 GLY T 216 GLY T 226	ZEN T 1 ( 3.8A) None SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.50A	1f5lA-1j17T: 15.2	1f5lA-1j17T: 36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1TNL_A_TPAA900_1 (TRYPSIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 6	ASP T 189 SER T 195 VAL T 213 GLY T 216 GLY T 226	ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.20A	1tnlA-1j17T: 43.0	1tnlA-1j17T: 71.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMZ_B_ROCB401_1 (PROTEASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 12	LEU T 137 GLY T 19 ASP T 189 GLY T 142 PRO T 198 ILE T 138	None None ZEN T 1 ( 3.8A) None None None	1.21A	2nmzA-1j17T: undetectable	2nmzA-1j17T: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OTF_A_2TNA201_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	4 / 5	LEU T 155 ILE T 73 SER T 32 GLY T 43	None	0.94A	2otfA-1j17T: undetectable	2otfA-1j17T: 18.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 6	ASP T 189 SER T 195 VAL T 213 GLY T 216 GLY T 226	ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.13A	2otvA-1j17T: 43.0	2otvA-1j17T: 71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2P16_A_GG2A298_1 (COAGULATION FACTOR X (EC 3.4.21.6) (STUART FACTOR) (STUART-PROWER FACTOR))	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	10 / 12	TYR T 99 PHE T 174 ASP T 189 ALA T 190 SER T 195 VAL T 213 TRP T 215 GLY T 216 GLY T 226 TYR T 228	ZEN T 1 (-3.8A) ZEN T 1 (-3.8A) ZEN T 1 ( 3.8A) ZEN T 1 (-3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A) ZEN T 1 (-3.6A)	0.37A	2p16A-1j17T: 36.4	2p16A-1j17T: 39.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VIN_A_505A1247_1 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR CHAIN B)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 8	ASP T 189 GLN T 192 SER T 195 VAL T 213 GLY T 216 GLY T 226	ZEN T 1 ( 3.8A) None SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.72A	2vinA-1j17T: 14.5	2vinA-1j17T: 36.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2W26_A_RIVA1001_1 (ACTIVATED FACTOR XA HEAVY CHAIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	11 / 12	TYR T 99 PHE T 174 ASP T 189 ALA T 190 SER T 195 VAL T 213 TRP T 215 GLY T 216 GLY T 219 GLY T 226 TYR T 228	ZEN T 1 (-3.8A) ZEN T 1 (-3.8A) ZEN T 1 ( 3.8A) ZEN T 1 (-3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-4.5A) ZEN T 1 (-3.7A) ZEN T 1 (-3.6A)	0.40A	2w26A-1j17T: 14.3	2w26A-1j17T: 39.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GY3_A_PNTA246_0 (CATIONIC TRYPSIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 11	HIS T 57 ASP T 189 SER T 195 TRP T 215 GLY T 216 GLY T 226	SO4 T 600 (-3.8A) ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.29A	3gy3A-1j17T: 41.7	3gy3A-1j17T: 71.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IAI_A_AZMA263_1 (CARBONIC ANHYDRASE 9)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 11	GLN T 81 VAL T 112 VAL T 66 LEU T 46 THR T 120	None	1.34A	3iaiA-1j17T: undetectable	3iaiA-1j17T: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IAI_B_AZMB263_1 (CARBONIC ANHYDRASE 9)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 11	GLN T 81 VAL T 112 VAL T 66 LEU T 46 THR T 120	None	1.34A	3iaiB-1j17T: undetectable	3iaiB-1j17T: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_D_DVAD8_0 (GRAMICIDIN D)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	3 / 3	VAL T 227 VAL T 213 TRP T 215	None ZEN T 1 (-4.1A) ZEN T 1 (-3.4A)	0.95A	3l8lC-1j17T: undetectable 3l8lD-1j17T: undetectable	3l8lC-1j17T: 5.12 3l8lD-1j17T: 6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MB5_A_SAMA301_0 (SAM-DEPENDENT METHYLTRANSFERASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	ILE T 212 VAL T 213 GLY T 44 ALA T 55 ILE T 73	None ZEN T 1 (-4.1A) None None None	0.97A	3mb5A-1j17T: undetectable	3mb5A-1j17T: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8W_A_FLPA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	VAL T 52 LEU T 68 ALA T 85 SER T 109 LEU T 108	None	0.96A	3n8wA-1j17T: 0.0	3n8wA-1j17T: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8Z_A_FLPA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	VAL T 52 LEU T 68 ALA T 85 SER T 109 LEU T 108	None	0.95A	3n8zA-1j17T: undetectable	3n8zA-1j17T: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_A_FLPA701_1 (CYCLOOXYGENASE-2)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	VAL T 52 LEU T 68 ALA T 85 SER T 109 LEU T 108	None	0.97A	3pghA-1j17T: undetectable	3pghA-1j17T: 16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGH_C_FLPC701_1 (CYCLOOXYGENASE-2)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	VAL T 52 LEU T 68 ALA T 85 SER T 109 LEU T 108	None	0.96A	3pghC-1j17T: undetectable	3pghC-1j17T: 16.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RXF_A_4APA9_1 (CATIONIC TRYPSIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 6	SER T 195 VAL T 213 TRP T 215 GLY T 216 GLY T 226	SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.18A	3rxfA-1j17T: 43.1	3rxfA-1j17T: 71.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RXH_A_HSMA7_1 (CATIONIC TRYPSIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	4 / 5	ASP T 189 SER T 195 VAL T 213 GLY T 226	ZEN T 1 ( 3.8A) SO4 T 600 ( 2.6A) ZEN T 1 (-4.1A) ZEN T 1 (-3.7A)	0.24A	3rxhA-1j17T: 43.1	3rxhA-1j17T: 71.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_B_VIVB301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	ILE T 89 VAL T 213 ILE T 242 ILE T 47 LEU T 209	None ZEN T 1 (-4.1A) None None None	1.01A	3w67B-1j17T: undetectable	3w67B-1j17T: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W67_D_VIVD301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	ILE T 242 ILE T 47 VAL T 121 LEU T 209 ILE T 212	None	1.17A	3w67D-1j17T: undetectable	3w67D-1j17T: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_F_W9TF512_1 (HEMOLYTIC LECTIN CEL-III)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	4 / 6	THR T 144 ASN T 143 GLY T 193 ILE T 73	None None SO4 T 600 (-3.8A) None	0.80A	3w9tF-1j17T: 0.0	3w9tF-1j17T: 20.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FU8_A_ACTA302_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	4 / 5	HIS T 57 GLN T 192 GLY T 193 SER T 195	SO4 T 600 (-3.8A) None SO4 T 600 (-3.8A) SO4 T 600 ( 2.6A)	0.73A	4fu8A-1j17T: 34.5	4fu8A-1j17T: 36.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4HFP_D_15UD402_1 (PROTHROMBIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 12	HIS T 57 ASP T 189 ALA T 190 VAL T 213 TRP T 215 GLY T 226	SO4 T 600 (-3.8A) ZEN T 1 ( 3.8A) ZEN T 1 (-3.8A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A)	0.28A	4hfpD-1j17T: 34.3	4hfpD-1j17T: 37.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PH9_A_IBPA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 10	VAL T 52 LEU T 68 ALA T 85 SER T 109 LEU T 108	None	1.00A	4ph9A-1j17T: undetectable	4ph9A-1j17T: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PH9_B_IBPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 10	VAL T 52 LEU T 68 ALA T 85 SER T 109 LEU T 108	None	0.99A	4ph9B-1j17T: undetectable	4ph9B-1j17T: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QDJ_A_SAMA301_0 (MAGNESIUM-PROTOPORPH YRIN O-METHYLTRANSFERASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	VAL T 231 GLY T 44 ILE T 103 LEU T 105 LEU T 46	None	1.03A	4qdjA-1j17T: undetectable	4qdjA-1j17T: 18.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RN6_B_15UB301_1 (THROMBIN HEAVY CHAIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	6 / 12	HIS T 57 ALA T 190 VAL T 213 TRP T 215 GLY T 216 GLY T 226	SO4 T 600 (-3.8A) ZEN T 1 (-3.8A) ZEN T 1 (-4.1A) ZEN T 1 (-3.4A) ZEN T 1 (-3.7A) ZEN T 1 (-3.7A)	0.72A	4rn6B-1j17T: 28.7	4rn6B-1j17T: 37.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FHZ_C_REAC602_1 (ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 10	GLY T 44 GLN T 239 ASN T 48 LEU T 46 LEU T 68	None	1.33A	5fhzC-1j17T: undetectable	5fhzC-1j17T: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KBW_A_RBFA201_1 (RIBOFLAVIN TRANSPORTER RIBU)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	LEU T 185 ASP T 189 GLY T 226 ASN T 224 ALA T 170	None ZEN T 1 ( 3.8A) ZEN T 1 (-3.7A) None None	1.42A	5kbwA-1j17T: undetectable	5kbwA-1j17T: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC0_A_RBFA303_1 (RIBOFLAVIN TRANSPORTER RIBU)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	LEU T 185 ASP T 189 GLY T 226 ASN T 224 ALA T 170	None ZEN T 1 ( 3.8A) ZEN T 1 (-3.7A) None None	1.41A	5kc0A-1j17T: undetectable	5kc0A-1j17T: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	GLY T 211 SER T 45 THR T 229 VAL T 181 VAL T 200	None	1.15A	5kocB-1j17T: undetectable	5kocB-1j17T: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	SER T 139 GLY T 211 SER T 45 THR T 229 VAL T 181	None	1.13A	5kocB-1j17T: undetectable	5kocB-1j17T: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MUG_A_VIVA301_1 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	3 / 3	SER T 214 SER T 195 PHE T 94	None SO4 T 600 ( 2.6A) None	0.91A	5mugA-1j17T: undetectable	5mugA-1j17T: 20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VIM_A_SAMA301_0 (METHYLTRANSFERASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	GLY T 142 GLY T 196 GLY T 43 GLY T 140 PHE T 94	None	0.90A	5vimA-1j17T: undetectable	5vimA-1j17T: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VIM_B_SAMB301_0 (METHYLTRANSFERASE)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 12	GLY T 142 GLY T 196 GLY T 43 GLY T 140 PHE T 94	None	0.92A	5vimB-1j17T: undetectable	5vimB-1j17T: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_H_PCFH604_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 8 CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL)	1j17	TRYPSIN II, ANIONIC (Rattus norvegicus)	5 / 8	GLY T 216 VAL T 183 GLY T 193 SER T 195 ALA T 55	ZEN T 1 (-3.7A) None SO4 T 600 (-3.8A) SO4 T 600 ( 2.6A) None	1.39A	6hu9H-1j17T: undetectable 6hu9e-1j17T: undetectable	6hu9H-1j17T: 14.69 6hu9e-1j17T: 22.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AQ7_B_AG2B4_1","TRYPSIN;AERUGINOSIN 98-B","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"HIS T  57;ASP T 189;SER T 195;VAL T 213;GLY T 216;GLY T 226","SO4 T 600 (-3.8A);ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.46A","1aq7A-1j17T:42.9","1aq7A-1j17T:71.75"],["1BCU_H_PRLH280_0","ALPHA-THROMBIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",7,"ASP T 189;ALA T 190;SER T 195;VAL T 213;TRP T 215;GLY T 216;GLY T 226","ZEN T   1 ( 3.8A);ZEN T   1 (-3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.32A","1bcuH-1j17T:18.7","1bcuH-1j17T:37.74"],["1DWC_H_MITH1_1","ALPHA-THROMBIN (LARGE SUBUNIT)","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"HIS T  57;ASP T 189;SER T 195;TRP T 215;GLY T 226","SO4 T 600 (-3.8A);ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A)","0.37A","1dwcH-1j17T:34.3","1dwcH-1j17T:37.74"],["1EQG_A_IBPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"VAL T  52;LEU T  68;ILE T  63;ALA T  85;SER T 109;LEU T 108","None","1.16A","1eqgA-1j17T:undetectable","1eqgA-1j17T:16.64"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"VAL T  52;LEU T  68;ILE T  63;ALA T  85;SER T 109;LEU T 108","None","1.16A","1eqgB-1j17T:undetectable","1eqgB-1j17T:16.64"],["1EQH_A_FLPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"VAL T  52;LEU T  68;ILE T  63;ALA T  85;SER T 109;LEU T 108","None","1.17A","1eqhA-1j17T:undetectable","1eqhA-1j17T:16.64"],["1EQH_B_FLPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"VAL T  52;LEU T  68;ILE T  63;ALA T  85;SER T 109;LEU T 108","None","1.16A","1eqhB-1j17T:undetectable","1eqhB-1j17T:16.64"],["1ETR_H_MITH1_1","EPSILON-THROMBIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",7,"HIS T  57;ASP T 189;SER T 195;VAL T 213;TRP T 215;GLY T 216;GLY T 226","SO4 T 600 (-3.8A);ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.49A","1etrH-1j17T:34.4","1etrH-1j17T:38.55"],["1F5L_A_AMRA301_1","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"ASP T 189;GLN T 192;SER T 195;VAL T 213;GLY T 216;GLY T 226","ZEN T   1 ( 3.8A);None;SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.50A","1f5lA-1j17T:15.2","1f5lA-1j17T:36.95"],["1TNL_A_TPAA900_1","TRYPSIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"ASP T 189;SER T 195;VAL T 213;GLY T 216;GLY T 226","ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.20A","1tnlA-1j17T:43.0","1tnlA-1j17T:71.75"],["2NMZ_B_ROCB401_1","PROTEASE;PROTEASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"LEU T 137;GLY T  19;ASP T 189;GLY T 142;PRO T 198;ILE T 138","None;None;ZEN T   1 ( 3.8A);None;None;None","1.21A","2nmzA-1j17T:undetectable","2nmzA-1j17T:17.54"],["2OTF_A_2TNA201_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",4,"LEU T 155;ILE T  73;SER T  32;GLY T  43","None","0.94A","2otfA-1j17T:undetectable","2otfA-1j17T:18.02"],["2OTV_A_NCAA1301_0","CATIONIC TRYPSIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"ASP T 189;SER T 195;VAL T 213;GLY T 216;GLY T 226","ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.13A","2otvA-1j17T:43.0","2otvA-1j17T:71.75"],["2P16_A_GG2A298_1","COAGULATION FACTOR X (EC 3.4.21.6) (STUART FACTOR) (STUART-PROWER FACTOR)","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",10,"TYR T  99;PHE T 174;ASP T 189;ALA T 190;SER T 195;VAL T 213;TRP T 215;GLY T 216;GLY T 226;TYR T 228","ZEN T   1 (-3.8A);ZEN T   1 (-3.8A);ZEN T   1 ( 3.8A);ZEN T   1 (-3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A);ZEN T   1 (-3.6A)","0.37A","2p16A-1j17T:36.4","2p16A-1j17T:39.50"],["2VIN_A_505A1247_1","UROKINASE-TYPE PLASMINOGEN ACTIVATOR CHAIN B","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"ASP T 189;GLN T 192;SER T 195;VAL T 213;GLY T 216;GLY T 226","ZEN T   1 ( 3.8A);None;SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.72A","2vinA-1j17T:14.5","2vinA-1j17T:36.95"],["2W26_A_RIVA1001_1","ACTIVATED FACTOR XA HEAVY CHAIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",11,"TYR T  99;PHE T 174;ASP T 189;ALA T 190;SER T 195;VAL T 213;TRP T 215;GLY T 216;GLY T 219;GLY T 226;TYR T 228","ZEN T   1 (-3.8A);ZEN T   1 (-3.8A);ZEN T   1 ( 3.8A);ZEN T   1 (-3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-4.5A);ZEN T   1 (-3.7A);ZEN T   1 (-3.6A)","0.40A","2w26A-1j17T:14.3","2w26A-1j17T:39.50"],["3GY3_A_PNTA246_0","CATIONIC TRYPSIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"HIS T  57;ASP T 189;SER T 195;TRP T 215;GLY T 216;GLY T 226","SO4 T 600 (-3.8A);ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.29A","3gy3A-1j17T:41.7","3gy3A-1j17T:71.75"],["3IAI_A_AZMA263_1","CARBONIC ANHYDRASE 9","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLN T  81;VAL T 112;VAL T  66;LEU T  46;THR T 120","None","1.34A","3iaiA-1j17T:undetectable","3iaiA-1j17T:20.37"],["3IAI_B_AZMB263_1","CARBONIC ANHYDRASE 9","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLN T  81;VAL T 112;VAL T  66;LEU T  46;THR T 120","None","1.34A","3iaiB-1j17T:undetectable","3iaiB-1j17T:20.37"],["3L8L_D_DVAD8_0","GRAMICIDIN D","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",3,"VAL T 227;VAL T 213;TRP T 215","None;ZEN T   1 (-4.1A);ZEN T   1 (-3.4A)","0.95A","3l8lC-1j17T:undetectable;3l8lD-1j17T:undetectable","3l8lC-1j17T:5.12;3l8lD-1j17T:6.05"],["3MB5_A_SAMA301_0","SAM-DEPENDENT METHYLTRANSFERASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"ILE T 212;VAL T 213;GLY T  44;ALA T  55;ILE T  73","None;ZEN T   1 (-4.1A);None;None;None","0.97A","3mb5A-1j17T:undetectable","3mb5A-1j17T:21.91"],["3N8W_A_FLPA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T  52;LEU T  68;ALA T  85;SER T 109;LEU T 108","None","0.96A","3n8wA-1j17T:0.0","3n8wA-1j17T:16.55"],["3N8Z_A_FLPA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T  52;LEU T  68;ALA T  85;SER T 109;LEU T 108","None","0.95A","3n8zA-1j17T:undetectable","3n8zA-1j17T:16.55"],["3PGH_A_FLPA701_1","CYCLOOXYGENASE-2","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T  52;LEU T  68;ALA T  85;SER T 109;LEU T 108","None","0.97A","3pghA-1j17T:undetectable","3pghA-1j17T:16.46"],["3PGH_C_FLPC701_1","CYCLOOXYGENASE-2","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T  52;LEU T  68;ALA T  85;SER T 109;LEU T 108","None","0.96A","3pghC-1j17T:undetectable","3pghC-1j17T:16.46"],["3RXF_A_4APA9_1","CATIONIC TRYPSIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"SER T 195;VAL T 213;TRP T 215;GLY T 216;GLY T 226","SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.18A","3rxfA-1j17T:43.1","3rxfA-1j17T:71.75"],["3RXH_A_HSMA7_1","CATIONIC TRYPSIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",4,"ASP T 189;SER T 195;VAL T 213;GLY T 226","ZEN T   1 ( 3.8A);SO4 T 600 ( 2.6A);ZEN T   1 (-4.1A);ZEN T   1 (-3.7A)","0.24A","3rxhA-1j17T:43.1","3rxhA-1j17T:71.75"],["3W67_B_VIVB301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"ILE T  89;VAL T 213;ILE T 242;ILE T  47;LEU T 209","None;ZEN T   1 (-4.1A);None;None;None","1.01A","3w67B-1j17T:undetectable","3w67B-1j17T:21.99"],["3W67_D_VIVD301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"ILE T 242;ILE T  47;VAL T 121;LEU T 209;ILE T 212","None","1.17A","3w67D-1j17T:undetectable","3w67D-1j17T:21.99"],["3W9T_F_W9TF512_1","HEMOLYTIC LECTIN CEL-III","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",4,"THR T 144;ASN T 143;GLY T 193;ILE T  73","None;None;SO4 T 600 (-3.8A);None","0.80A","3w9tF-1j17T:0.0","3w9tF-1j17T:20.05"],["4FU8_A_ACTA302_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",4,"HIS T  57;GLN T 192;GLY T 193;SER T 195","SO4 T 600 (-3.8A);None;SO4 T 600 (-3.8A);SO4 T 600 ( 2.6A)","0.73A","4fu8A-1j17T:34.5","4fu8A-1j17T:36.99"],["4HFP_D_15UD402_1","PROTHROMBIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"HIS T  57;ASP T 189;ALA T 190;VAL T 213;TRP T 215;GLY T 226","SO4 T 600 (-3.8A);ZEN T   1 ( 3.8A);ZEN T   1 (-3.8A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A)","0.28A","4hfpD-1j17T:34.3","4hfpD-1j17T:37.35"],["4PH9_A_IBPA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T  52;LEU T  68;ALA T  85;SER T 109;LEU T 108","None","1.00A","4ph9A-1j17T:undetectable","4ph9A-1j17T:16.27"],["4PH9_B_IBPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T  52;LEU T  68;ALA T  85;SER T 109;LEU T 108","None","0.99A","4ph9B-1j17T:undetectable","4ph9B-1j17T:16.27"],["4QDJ_A_SAMA301_0","MAGNESIUM-PROTOPORPHYRIN O-METHYLTRANSFERASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"VAL T 231;GLY T  44;ILE T 103;LEU T 105;LEU T  46","None","1.03A","4qdjA-1j17T:undetectable","4qdjA-1j17T:18.65"],["4RN6_B_15UB301_1","THROMBIN HEAVY CHAIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",6,"HIS T  57;ALA T 190;VAL T 213;TRP T 215;GLY T 216;GLY T 226","SO4 T 600 (-3.8A);ZEN T   1 (-3.8A);ZEN T   1 (-4.1A);ZEN T   1 (-3.4A);ZEN T   1 (-3.7A);ZEN T   1 (-3.7A)","0.72A","4rn6B-1j17T:28.7","4rn6B-1j17T:37.35"],["5FHZ_C_REAC602_1","ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLY T  44;GLN T 239;ASN T  48;LEU T  46;LEU T  68","None","1.33A","5fhzC-1j17T:undetectable","5fhzC-1j17T:17.29"],["5KBW_A_RBFA201_1","RIBOFLAVIN TRANSPORTER RIBU","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"LEU T 185;ASP T 189;GLY T 226;ASN T 224;ALA T 170","None;ZEN T   1 ( 3.8A);ZEN T   1 (-3.7A);None;None","1.42A","5kbwA-1j17T:undetectable","5kbwA-1j17T:20.92"],["5KC0_A_RBFA303_1","RIBOFLAVIN TRANSPORTER RIBU","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"LEU T 185;ASP T 189;GLY T 226;ASN T 224;ALA T 170","None;ZEN T   1 ( 3.8A);ZEN T   1 (-3.7A);None;None","1.41A","5kc0A-1j17T:undetectable","5kc0A-1j17T:21.55"],["5KOC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLY T 211;SER T  45;THR T 229;VAL T 181;VAL T 200","None","1.15A","5kocB-1j17T:undetectable","5kocB-1j17T:20.31"],["5KOC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"SER T 139;GLY T 211;SER T  45;THR T 229;VAL T 181","None","1.13A","5kocB-1j17T:undetectable","5kocB-1j17T:20.31"],["5MUG_A_VIVA301_1","ALPHA-TOCOPHEROL TRANSFER PROTEIN","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",3,"SER T 214;SER T 195;PHE T  94","None;SO4 T 600 ( 2.6A);None","0.91A","5mugA-1j17T:undetectable","5mugA-1j17T:20.38"],["5VIM_A_SAMA301_0","METHYLTRANSFERASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLY T 142;GLY T 196;GLY T  43;GLY T 140;PHE T  94","None","0.90A","5vimA-1j17T:undetectable","5vimA-1j17T:20.73"],["5VIM_B_SAMB301_0","METHYLTRANSFERASE","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLY T 142;GLY T 196;GLY T  43;GLY T 140;PHE T  94","None","0.92A","5vimB-1j17T:undetectable","5vimB-1j17T:20.73"],["6HU9_H_PCFH604_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 8;CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL","1j17","TRYPSIN II, ANIONIC","Rattus norvegicus",5,"GLY T 216;VAL T 183;GLY T 193;SER T 195;ALA T  55","ZEN T   1 (-3.7A);None;SO4 T 600 (-3.8A);SO4 T 600 ( 2.6A);None","1.39A","6hu9H-1j17T:undetectable;6hu9e-1j17T:undetectable","6hu9H-1j17T:14.69;6hu9e-1j17T:22.87"]]