SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Escherichia
coli) 		3 / 3 PRO A 423
ASP A 427
ASP A 433
 None
 0.76A 1sqfA-1j1vA:
undetectable		 1sqfA-1j1vA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Escherichia
coli) 		4 / 6 CYH A 441
ILE A 444
GLN A 408
ILE A 425
 None
 1.16A 4w5tA-1j1vA:
undetectable		 4w5tA-1j1vA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Escherichia
coli) 		5 / 12 LEU A 465
LEU A 417
ILE A 379
ILE A 376
ILE A 425
 None
 1.03A 4y0rA-1j1vA:
undetectable		 4y0rA-1j1vA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Escherichia
coli) 		4 / 6 CYH A 441
ILE A 444
GLN A 408
ILE A 425
 None
 1.14A 4z4cA-1j1vA:
undetectable		 4z4cA-1j1vA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Escherichia
coli) 		3 / 3 ASP A 457
VAL A 383
LEU A 413
 None
 0.50A 5e5jB-1j1vA:
undetectable		 5e5jB-1j1vA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA
(Escherichia
coli) 		3 / 3 LYS A 443
LEU A 447
ARG A 405
 None
 0.94A 5yw0A-1j1vA:
undetectable		 5yw0A-1j1vA:
16.56