SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		4 / 6 PHE A 158
GLU A 124
LEU A 123
VAL A  23
 None
 0.98A 1hk1A-1j2rA:
0.0		 1hk1A-1j2rA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		4 / 7 PHE A 158
GLU A 124
LEU A 123
VAL A  23
 None
 0.96A 1hk3A-1j2rA:
undetectable		 1hk3A-1j2rA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		4 / 8 ALA A  53
ALA A  48
ARG A  47
LEU A  27
 None
 0.94A 2bxmA-1j2rA:
undetectable		 2bxmA-1j2rA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		5 / 10 VAL A  44
VAL A  45
ASP A  26
ILE A  25
VAL A  24
 None
 1.12A 2qboA-1j2rA:
0.0		 2qboA-1j2rA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		4 / 8 SER A 178
PHE A 118
GLY A 116
ILE A  25
 None
 0.91A 3aodA-1j2rA:
undetectable		 3aodA-1j2rA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		5 / 10 PHE A 118
GLU A 155
LEU A 160
LEU A 137
ILE A 135
 None
 1.34A 3kvrA-1j2rA:
undetectable		 3kvrA-1j2rA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		5 / 10 PHE A 118
GLU A 155
LEU A 160
LEU A 137
ILE A 135
 None
 1.35A 3kvrB-1j2rA:
undetectable		 3kvrB-1j2rA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		3 / 3 TRP A  95
VAL A  89
TRP A  94
 None
 0.91A 3zq8C-1j2rA:
undetectable
3zq8D-1j2rA:
undetectable		 3zq8C-1j2rA:
8.00
3zq8D-1j2rA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		5 / 12 ALA A 150
THR A 149
LEU A 137
PRO A 184
ALA A 187
 None
 1.22A 4ypmA-1j2rA:
undetectable		 4ypmA-1j2rA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		5 / 10 SER A  58
GLY A  59
ILE A 132
ALA A  21
LEU A  22
 None
 1.38A 5zjiA-1j2rA:
undetectable
5zjiJ-1j2rA:
0.0		 5zjiA-1j2rA:
18.59
5zjiJ-1j2rA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD
(Escherichia
coli) 		3 / 3 GLY A 131
ASP A 133
ILE A 135
 None
 0.58A 6dgxB-1j2rA:
undetectable		 6dgxB-1j2rA:
19.46