SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 10 GLY A 247
VAL A  95
ILE A  76
TYR A 282
GLY A 234
 None
 1.19A 1fohA-1j32A:
undetectable		 1fohA-1j32A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 10 GLY A 247
VAL A  95
ILE A  76
TYR A 282
GLY A 234
 None
 1.18A 1fohB-1j32A:
0.0		 1fohB-1j32A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 6 ALA A 187
TYR A 180
ILE A 156
PRO A 153
 None
 1.20A 1oniB-1j32A:
undetectable
1oniC-1j32A:
undetectable		 1oniB-1j32A:
16.58
1oniC-1j32A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 10 GLY A 247
VAL A  95
ILE A  76
TYR A 282
GLY A 234
 None
 1.20A 1pn0A-1j32A:
0.0		 1pn0A-1j32A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 10 GLY A 247
VAL A  95
ILE A  76
TYR A 282
GLY A 234
 None
 1.20A 1pn0B-1j32A:
0.0		 1pn0B-1j32A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 9 LEU A 313
LEU A 384
VAL A 348
ALA A 349
PHE A 338
 None
 1.04A 1tbfA-1j32A:
undetectable		 1tbfA-1j32A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 6 SER A 233
ILE A 204
ALA A 236
ALA A 278
 None
PLP  A 413 ( 3.9A)
PLP  A 413 (-3.4A)
None
 0.64A 1w0gA-1j32A:
0.0		 1w0gA-1j32A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 ILE A 262
ALA A 259
THR A  96
VAL A 230
LEU A  80
 None
 1.07A 2g78A-1j32A:
undetectable		 2g78A-1j32A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 LEU A 255
ILE A 262
ALA A 259
THR A  96
VAL A 230
 None
 1.10A 2g78A-1j32A:
undetectable		 2g78A-1j32A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 LEU A 313
LEU A 384
VAL A 348
ALA A 349
PHE A 338
 None
 1.03A 2h42C-1j32A:
0.0		 2h42C-1j32A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 LEU A 384
VAL A 348
ALA A 349
ILE A  18
PHE A 338
 None
 1.12A 2h42C-1j32A:
0.0		 2h42C-1j32A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 5 GLY A 196
TRP A 198
ARG A 228
LEU A 197
 None
 1.38A 2j2pD-1j32A:
0.0
2j2pF-1j32A:
0.0		 2j2pD-1j32A:
20.22
2j2pF-1j32A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 10 TYR A 366
PRO A 175
MET A 324
ASP A 319
PRO A 122
 None
 1.35A 3lsfB-1j32A:
0.0
3lsfE-1j32A:
undetectable		 3lsfB-1j32A:
22.05
3lsfE-1j32A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		3 / 3 ARG A 245
VAL A  49
THR A  44
 PLP  A 413 (-2.8A)
None
None
 0.84A 3nduD-1j32A:
0.0		 3nduD-1j32A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 10 PRO A 326
TYR A 323
GLY A 353
PHE A 325
SER A 365
 None
 1.35A 4mmdA-1j32A:
0.0		 4mmdA-1j32A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		3 / 3 PRO A 128
MET A 130
TYR A 127
 None
 1.01A 4qa2B-1j32A:
2.4		 4qa2B-1j32A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		3 / 3 GLY A  64
PRO A  65
GLN A 275
 None
 0.57A 4qwpB-1j32A:
0.0		 4qwpB-1j32A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_C_EF2C151_1
(CEREBLON ISOFORM 4)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 7 ASN A 174
PRO A 175
PHE A 325
TYR A 366
 PLP  A 413 (-3.7A)
None
None
None
 1.49A 4v2yC-1j32A:
0.0		 4v2yC-1j32A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 8 ASN A 174
PRO A 175
PHE A 325
TYR A 366
 PLP  A 413 (-3.7A)
None
None
None
 1.49A 4v2zC-1j32A:
0.0		 4v2zC-1j32A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 7 ASN A 174
PRO A 175
PHE A 325
TYR A 366
 PLP  A 413 (-3.7A)
None
None
None
 1.41A 5amhA-1j32A:
0.0		 5amhA-1j32A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 7 ASN A 174
PRO A 175
PHE A 325
TYR A 366
 PLP  A 413 (-3.7A)
None
None
None
 1.29A 5amjA-1j32A:
undetectable		 5amjA-1j32A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 7 PRO A 128
VAL A 131
ILE A 111
VAL A 117
ILE A 119
 None
 1.47A 5bmvC-1j32A:
2.5		 5bmvC-1j32A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 11 GLU A  69
THR A 272
ARG A  71
GLY A  59
ALA A  55
 None
 1.33A 5e3iB-1j32A:
undetectable		 5e3iB-1j32A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		3 / 3 SER A  36
LEU A 307
MET A 324
 None
 0.84A 5ikrB-1j32A:
0.0		 5ikrB-1j32A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 5 ILE A 208
LEU A 304
LYS A 317
VAL A 179
 None
 1.22A 5jmnB-1j32A:
0.0		 5jmnB-1j32A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 ILE A 387
GLY A 386
LEU A 313
LEU A 307
LEU A 380
 None
 1.00A 5nfjA-1j32A:
undetectable		 5nfjA-1j32A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 LEU A 166
LEU A 106
ILE A 218
LEU A 197
PRO A 252
 None
 1.17A 5og9B-1j32A:
0.0		 5og9B-1j32A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 7 ASN A 174
PRO A 175
PHE A 325
TYR A 366
 PLP  A 413 (-3.7A)
None
None
None
 1.29A 5oh3A-1j32A:
0.0		 5oh3A-1j32A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 9 SER A 327
THR A 331
ALA A 329
GLY A 312
LEU A 384
 None
 1.29A 5vw4A-1j32A:
undetectable		 5vw4A-1j32A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 5 TYR A 366
ARG A 300
MET A 303
LEU A 307
 None
 1.26A 5x19J-1j32A:
0.0		 5x19J-1j32A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		4 / 5 TYR A 366
ARG A 300
MET A 303
LEU A 307
 None
 1.23A 5x1bJ-1j32A:
0.0		 5x1bJ-1j32A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 1j32 ASPARTATE
AMINOTRANSFERASE
(Phormidium
lapideum) 		5 / 12 LYS A 150
VAL A 151
SER A 201
VAL A 185
ILE A 188
 None
 1.47A 6gsdA-1j32A:
undetectable		 6gsdA-1j32A:
11.58