SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.85A 1a7yB-1j3eA:
undetectable		 1a7yB-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.89A 1dscC-1j3eA:
undetectable		 1dscC-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  70
THR A  84
PRO A  72
 None
 0.80A 1dscC-1j3eA:
undetectable		 1dscC-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  70
THR A  84
PRO A  72
 None
 0.84A 1fjaC-1j3eA:
undetectable		 1fjaC-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  70
THR A  84
PRO A  72
 None
 0.85A 1fjaD-1j3eA:
undetectable		 1fjaD-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.87A 1unjL-1j3eA:
undetectable		 1unjL-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.87A 1unjR-1j3eA:
undetectable		 1unjR-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.86A 1unjX-1j3eA:
undetectable		 1unjX-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.85A 1unmE-1j3eA:
undetectable		 1unmE-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  70
THR A  84
PRO A  72
 None
 0.86A 1unmF-1j3eA:
undetectable		 1unmF-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  70
THR A  84
PRO A  72
 None
 0.85A 209dC-1j3eA:
undetectable		 209dC-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.80A 316dC-1j3eA:
undetectable		 316dC-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		5 / 12 ILE A 109
PHE A  56
LEU A  48
GLN A 100
PHE A  26
 None
 1.06A 3apwB-1j3eA:
0.0		 3apwB-1j3eA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 THR A  84
PRO A  72
THR A  70
 None
 0.87A 4hivD-1j3eA:
undetectable		 4hivD-1j3eA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		4 / 6 LEU A  11
TYR A  16
ILE A  95
THR A  32
 None
 1.03A 4l39A-1j3eA:
undetectable		 4l39A-1j3eA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		5 / 12 PRO A 105
ILE A  95
LEU A 108
LEU A  48
THR A  45
 None
 1.25A 5tiwB-1j3eA:
undetectable		 5tiwB-1j3eA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1j3e SEQA PROTEIN
(Escherichia
coli) 		3 / 3 TYR A  55
ARG A  53
THR A  52
 None
 1.01A 5z84J-1j3eA:
0.0		 5z84J-1j3eA:
19.82