SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FIQ_C_SALC1335_1 (XANTHINE OXIDASE)	1j3m	THE CONSERVED HYPOTHETICAL PROTEIN TT1751 (Thermus thermophilus)	4 / 8	LEU A 82 THR A 7 LEU A 129 ALA A 10	None	0.82A	1fiqC-1j3mA: undetectable	1fiqC-1j3mA: 11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EGV_A_SAMA1300_0 (UPF0088 PROTEIN AQ_165)	1j3m	THE CONSERVED HYPOTHETICAL PROTEIN TT1751 (Thermus thermophilus)	5 / 12	LEU A 82 LEU A 92 THR A 7 LEU A 8 ALA A 15	None	0.76A	2egvA-1j3mA: undetectable	2egvA-1j3mA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9S_C_BEZC264_0 (CARNITINYL-COA DEHYDRATASE)	1j3m	THE CONSERVED HYPOTHETICAL PROTEIN TT1751 (Thermus thermophilus)	4 / 6	ALA A 65 ILE A 72 LEU A 111 ALA A 118	None	0.86A	3r9sC-1j3mA: undetectable	3r9sC-1j3mA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UNI_B_SALB1345_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1j3m	THE CONSERVED HYPOTHETICAL PROTEIN TT1751 (Thermus thermophilus)	4 / 8	LEU A 82 THR A 7 LEU A 129 ALA A 10	None	0.81A	3uniB-1j3mA: undetectable	3uniB-1j3mA: 7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PXM_B_ESTB2000_1 (ESTROGEN RECEPTOR)	1j3m	THE CONSERVED HYPOTHETICAL PROTEIN TT1751 (Thermus thermophilus)	5 / 11	LEU A 61 ALA A 62 LEU A 76 GLY A 55 LEU A 31	None	1.23A	4pxmB-1j3mA: undetectable	4pxmB-1j3mA: 19.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FIQ_C_SALC1335_1","XANTHINE OXIDASE","1j3m","THE CONSERVED HYPOTHETICAL PROTEIN TT1751","Thermus thermophilus",4,"LEU A  82;THR A   7;LEU A 129;ALA A  10","None","0.82A","1fiqC-1j3mA:undetectable","1fiqC-1j3mA:11.21"],["2EGV_A_SAMA1300_0","UPF0088 PROTEIN AQ_165","1j3m","THE CONSERVED HYPOTHETICAL PROTEIN TT1751","Thermus thermophilus",5,"LEU A  82;LEU A  92;THR A   7;LEU A   8;ALA A  15","None","0.76A","2egvA-1j3mA:undetectable","2egvA-1j3mA:20.17"],["3R9S_C_BEZC264_0","CARNITINYL-COA DEHYDRATASE","1j3m","THE CONSERVED HYPOTHETICAL PROTEIN TT1751","Thermus thermophilus",4,"ALA A  65;ILE A  72;LEU A 111;ALA A 118","None","0.86A","3r9sC-1j3mA:undetectable","3r9sC-1j3mA:20.23"],["3UNI_B_SALB1345_1","XANTHINE DEHYDROGENASE\/OXIDASE","1j3m","THE CONSERVED HYPOTHETICAL PROTEIN TT1751","Thermus thermophilus",4,"LEU A  82;THR A   7;LEU A 129;ALA A  10","None","0.81A","3uniB-1j3mA:undetectable","3uniB-1j3mA:7.25"],["4PXM_B_ESTB2000_1","ESTROGEN RECEPTOR","1j3m","THE CONSERVED HYPOTHETICAL PROTEIN TT1751","Thermus thermophilus",5,"LEU A  61;ALA A  62;LEU A  76;GLY A  55;LEU A  31","None","1.23A","4pxmB-1j3mA:undetectable","4pxmB-1j3mA:19.85"]]