SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 1j3p PHOSPHOGLUCOSE
ISOMERASE
(Thermococcus
litoralis) 		4 / 8 HIS A  91
GLU A  98
HIS A 137
ALA A 151
 FE  A 201 (-4.4A)
FE  A 201 (-2.8A)
None
None
 1.01A 2bnnA-1j3pA:
9.7
2bnnB-1j3pA:
9.1		 2bnnA-1j3pA:
18.14
2bnnB-1j3pA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)		 1j3p PHOSPHOGLUCOSE
ISOMERASE
(Thermococcus
litoralis) 		5 / 10 HIS A  89
HIS A  91
HIS A 137
THR A  86
PHE A 149
 FE  A 201 (-4.1A)
FE  A 201 (-4.4A)
None
None
None
 1.19A 2dttD-1j3pA:
undetectable
2dttF-1j3pA:
undetectable		 2dttD-1j3pA:
24.21
2dttF-1j3pA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j3p PHOSPHOGLUCOSE
ISOMERASE
(Thermococcus
litoralis) 		3 / 3 HIS A  91
HIS A  89
HIS A 159
 FE  A 201 (-4.4A)
FE  A 201 (-4.1A)
FE  A 201 (-4.2A)
 0.73A 3ag4A-1j3pA:
undetectable		 3ag4A-1j3pA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j3p PHOSPHOGLUCOSE
ISOMERASE
(Thermococcus
litoralis) 		3 / 3 HIS A  91
HIS A  89
HIS A 159
 FE  A 201 (-4.4A)
FE  A 201 (-4.1A)
FE  A 201 (-4.2A)
 0.75A 3ag4N-1j3pA:
undetectable		 3ag4N-1j3pA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 1j3p PHOSPHOGLUCOSE
ISOMERASE
(Thermococcus
litoralis) 		4 / 7 LYS A  87
TYR A  34
LYS A 167
GLU A 166
 None
 1.11A 3hs4A-1j3pA:
undetectable		 3hs4A-1j3pA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1j3p PHOSPHOGLUCOSE
ISOMERASE
(Thermococcus
litoralis) 		4 / 5 LEU A  11
PHE A  13
LEU A 103
PHE A 101
 None
 1.04A 5x19C-1j3pA:
undetectable
5x19J-1j3pA:
undetectable		 5x19C-1j3pA:
21.27
5x19J-1j3pA:
17.44