SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.82A 1a7yA-1j3uA:
undetectable		 1a7yA-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.85A 1a7yB-1j3uA:
undetectable		 1a7yB-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.87A 1a7yB-1j3uA:
undetectable		 1a7yB-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.72A 1dscC-1j3uA:
undetectable		 1dscC-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.87A 1fjaC-1j3uA:
undetectable		 1fjaC-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.87A 1fjaD-1j3uA:
undetectable		 1fjaD-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.83A 1i3wE-1j3uA:
undetectable		 1i3wE-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.84A 1i3wF-1j3uA:
undetectable		 1i3wF-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.87A 1i3wG-1j3uA:
undetectable		 1i3wG-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.79A 1i3wG-1j3uA:
undetectable		 1i3wG-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.80A 1i3wH-1j3uA:
undetectable		 1i3wH-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.80A 1mnvD-1j3uA:
undetectable		 1mnvD-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.78A 1mnvD-1j3uA:
undetectable		 1mnvD-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.81A 1qfiA-1j3uA:
undetectable		 1qfiA-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		6 / 12 ALA A  57
VAL A 135
GLY A  50
ILE A  82
ALA A 115
ILE A  74
 None
 1.23A 1rl8A-1j3uA:
undetectable		 1rl8A-1j3uA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.81A 1unjF-1j3uA:
undetectable		 1unjF-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.84A 1unjF-1j3uA:
undetectable		 1unjF-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.80A 1unjL-1j3uA:
undetectable		 1unjL-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.77A 1unjL-1j3uA:
undetectable		 1unjL-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.77A 1unjR-1j3uA:
undetectable		 1unjR-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.77A 1unjR-1j3uA:
undetectable		 1unjR-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.77A 1unjW-1j3uA:
undetectable		 1unjW-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.76A 1unjX-1j3uA:
undetectable		 1unjX-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.76A 1unjX-1j3uA:
undetectable		 1unjX-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.78A 1unmE-1j3uA:
undetectable		 1unmE-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.77A 1unmE-1j3uA:
undetectable		 1unmE-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.81A 1unmF-1j3uA:
undetectable		 1unmF-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 147
THR A 149
PRO A 146
 None
 0.77A 1unmF-1j3uA:
undetectable		 1unmF-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 6 ASN A 368
ILE A 375
GLN A 371
THR A  37
 None
 1.27A 2hkkA-1j3uA:
undetectable		 2hkkA-1j3uA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 7 ILE A 291
ARG A 296
ILE A 309
PHE A 201
 None
 1.10A 2q6hA-1j3uA:
0.1		 2q6hA-1j3uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 6 ILE A 291
ARG A 296
ILE A 309
PHE A 201
 None
 1.12A 2q72A-1j3uA:
0.1		 2q72A-1j3uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 7 ILE A 291
ARG A 296
ILE A 309
PHE A 201
 None
 1.12A 2qb4A-1j3uA:
0.8		 2qb4A-1j3uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		5 / 10 PHE A 178
GLY A 198
ALA A 203
PHE A 201
LEU A 295
 None
 1.34A 3a3yA-1j3uA:
undetectable		 3a3yA-1j3uA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		5 / 12 PRO A 330
LEU A 311
ASN A 293
VAL A 181
LEU A 197
 None
 1.12A 3a51B-1j3uA:
0.9		 3a51B-1j3uA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		5 / 8 ALA A  57
VAL A 135
GLY A  50
ILE A  82
ILE A  74
 None
 1.19A 3ekpA-1j3uA:
undetectable		 3ekpA-1j3uA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		6 / 10 ALA A  57
VAL A 135
GLY A  50
ILE A  82
ALA A 115
ILE A  74
 None
 1.18A 3ekpC-1j3uA:
undetectable		 3ekpC-1j3uA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		6 / 9 ALA A  57
VAL A 135
GLY A  50
ILE A  82
ALA A 115
ILE A  74
 None
 1.20A 3ektB-1j3uA:
undetectable		 3ektB-1j3uA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		5 / 9 LEU A 295
ASP A 294
GLY A 185
ILE A 195
ILE A 309
 None
 1.04A 3s56B-1j3uA:
undetectable		 3s56B-1j3uA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 5 PHE A 253
ILE A  46
LEU A  49
LYS A  47
 None
 1.32A 3sueC-1j3uA:
undetectable		 3sueC-1j3uA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		5 / 11 GLN A 139
THR A 141
ALA A 144
LEU A  49
ASN A 136
 None
 1.39A 4claA-1j3uA:
undetectable		 4claA-1j3uA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 8 ILE A  46
LEU A  49
ILE A 370
GLY A 100
 None
 0.85A 4hb6A-1j3uA:
undetectable		 4hb6A-1j3uA:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 8 ILE A  46
LEU A  49
ILE A 370
GLY A 100
 None
 0.81A 4hb8A-1j3uA:
undetectable		 4hb8A-1j3uA:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 THR A 149
PRO A 146
THR A 147
 None
 0.83A 4hivD-1j3uA:
undetectable		 4hivD-1j3uA:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 7 ALA A 148
PRO A 146
LEU A  45
LEU A  49
 None
 1.01A 4iomA-1j3uA:
undetectable		 4iomA-1j3uA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 6 LEU A 369
MET A 376
LEU A 157
ILE A 151
 None
 1.16A 4okxA-1j3uA:
1.1		 4okxA-1j3uA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		4 / 7 GLY A 354
GLN A 355
SER A 351
ASN A 359
 None
 1.00A 4ws0A-1j3uA:
undetectable		 4ws0A-1j3uA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 ARG A 210
ASN A 287
ASP A 294
 None
 0.78A 5gwxA-1j3uA:
undetectable		 5gwxA-1j3uA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1j3u ASPARTASE
(Bacillus
sp.
YM55-1) 		3 / 3 GLN A  89
TRP A  86
VAL A  81
 None
 1.15A 6auuA-1j3uA:
0.0		 6auuA-1j3uA:
22.94