SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j4j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1j4j TABTOXIN RESISTANCE
PROTEIN
(Pseudomonas
amygdali) 		4 / 8 MET A 123
LEU A  92
LEU A  73
LEU A 138
 None
 0.86A 1ereE-1j4jA:
undetectable		 1ereE-1j4jA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1j4j TABTOXIN RESISTANCE
PROTEIN
(Pseudomonas
amygdali) 		4 / 8 MET A 123
LEU A  92
LEU A  73
LEU A 138
 None
 0.85A 1ereF-1j4jA:
undetectable		 1ereF-1j4jA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1j4j TABTOXIN RESISTANCE
PROTEIN
(Pseudomonas
amygdali) 		3 / 3 ALA A  33
ARG A  29
LYS A  65
 None
 1.02A 3kp5B-1j4jA:
undetectable		 3kp5B-1j4jA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1j4j TABTOXIN RESISTANCE
PROTEIN
(Pseudomonas
amygdali) 		4 / 6 ALA A  88
LEU A 107
MET A 108
LEU A  35
 None
ACO  A 301 (-3.9A)
None
None
 1.05A 4xoyA-1j4jA:
undetectable		 4xoyA-1j4jA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1j4j TABTOXIN RESISTANCE
PROTEIN
(Pseudomonas
amygdali) 		4 / 6 ALA A  88
GLN A  89
LEU A 107
MET A 108
 None
None
ACO  A 301 (-3.9A)
None
 1.25A 4xp3A-1j4jA:
undetectable		 4xp3A-1j4jA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 1j4j TABTOXIN RESISTANCE
PROTEIN
(Pseudomonas
amygdali) 		4 / 6 ALA A  88
LEU A 107
MET A 108
LEU A  35
 None
ACO  A 301 (-3.9A)
None
None
 1.09A 4xp3A-1j4jA:
undetectable		 4xp3A-1j4jA:
18.55