SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1j6q CYTOCHROME C
MATURATION PROTEIN E
(Shewanella
putrefaciens) 		5 / 12 HIS A  85
GLU A  91
GLY A  90
GLY A  89
GLY A 109
 None
 0.92A 1n2xB-1j6qA:
undetectable		 1n2xB-1j6qA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1j6q CYTOCHROME C
MATURATION PROTEIN E
(Shewanella
putrefaciens) 		3 / 3 VAL A  66
VAL A 111
ASP A  97
 None
 0.70A 2fumD-1j6qA:
undetectable		 2fumD-1j6qA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 1j6q CYTOCHROME C
MATURATION PROTEIN E
(Shewanella
putrefaciens) 		5 / 12 GLN A  81
GLU A 118
LEU A  93
ILE A  92
ASP A 119
 None
 1.27A 5vlmG-1j6qA:
undetectable		 5vlmG-1j6qA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1j6q CYTOCHROME C
MATURATION PROTEIN E
(Shewanella
putrefaciens) 		4 / 5 GLN A  58
VAL A 115
PRO A  54
THR A  95
 None
 1.10A 6cduA-1j6qA:
undetectable
6cduB-1j6qA:
undetectable		 6cduA-1j6qA:
17.33
6cduB-1j6qA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1j6q CYTOCHROME C
MATURATION PROTEIN E
(Shewanella
putrefaciens) 		4 / 6 GLN A  58
PRO A  54
ALA A 123
THR A  95
 None
 1.03A 6cduB-1j6qA:
undetectable
6cduC-1j6qA:
undetectable		 6cduB-1j6qA:
17.33
6cduC-1j6qA:
17.33