SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		4 / 4 ARG A  42
ALA A  43
ALA A 115
GLU A 111
 None
 1.22A 1e7bA-1j6rA:
undetectable		 1e7bA-1j6rA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		5 / 11 GLU A 105
GLY A 110
ILE A 103
ALA A 115
ARG A  42
 None
 1.00A 1x7pA-1j6rA:
undetectable
1x7pB-1j6rA:
undetectable		 1x7pA-1j6rA:
19.54
1x7pB-1j6rA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		4 / 7 VAL A 133
LYS A 132
TRP A  57
GLU A   7
 None
 1.22A 3hs4A-1j6rA:
undetectable		 3hs4A-1j6rA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		4 / 8 LEU A  82
SER A  83
LEU A 161
ILE A  88
 None
 0.92A 3ln1A-1j6rA:
0.5		 3ln1A-1j6rA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		4 / 8 ASP A 134
GLU A 127
ILE A 190
TYR A 154
 None
 1.01A 5cfsA-1j6rA:
undetectable		 5cfsA-1j6rA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		5 / 7 LEU A 157
SER A 151
LEU A  82
THR A  79
ALA A  78
 None
 1.44A 5o96C-1j6rA:
undetectable		 5o96C-1j6rA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1j6r METHIONINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 LEU A  47
GLY A  96
ALA A  50
THR A  94
VAL A  55
 None
 1.35A 5x6yA-1j6rA:
undetectable		 5x6yA-1j6rA:
14.32