SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j6x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		4 / 8 VAL A  20
TYR A  37
THR A  95
LEU A 101
 None
 0.85A 1z2bB-1j6xA:
undetectable		 1z2bB-1j6xA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.72A 2dysA-1j6xA:
undetectable		 2dysA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.72A 2dysN-1j6xA:
undetectable		 2dysN-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.73A 2eikA-1j6xA:
undetectable		 2eikA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.74A 2eilA-1j6xA:
undetectable		 2eilA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.76A 2eilN-1j6xA:
undetectable		 2eilN-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.74A 2eimN-1j6xA:
undetectable		 2eimN-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.69A 2einA-1j6xA:
undetectable		 2einA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.72A 2einN-1j6xA:
undetectable		 2einN-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		4 / 8 PHE A  41
GLY A  83
GLY A 132
MET A 105
 None
 0.93A 2y6rB-1j6xA:
undetectable		 2y6rB-1j6xA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.74A 3s33A-1j6xA:
undetectable		 3s33A-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.74A 3s38A-1j6xA:
0.9		 3s38A-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.72A 3s39A-1j6xA:
undetectable		 3s39A-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.75A 3s3aA-1j6xA:
undetectable		 3s3aA-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.73A 3s3bA-1j6xA:
undetectable		 3s3bA-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.73A 3s3cA-1j6xA:
undetectable		 3s3cA-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.72A 3s3dA-1j6xA:
undetectable		 3s3dA-1j6xA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.74A 3x2qA-1j6xA:
undetectable		 3x2qA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 ASN A 127
TRP A 124
ASP A  50
 None
 1.30A 4a7tA-1j6xA:
0.0
4a7tF-1j6xA:
0.0		 4a7tA-1j6xA:
19.76
4a7tF-1j6xA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		4 / 5 TYR A  19
ARG A  21
ASP A  24
VAL A  72
 None
 1.45A 4nkvB-1j6xA:
0.0		 4nkvB-1j6xA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.78A 5z84N-1j6xA:
undetectable		 5z84N-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.76A 5zcpA-1j6xA:
undetectable		 5zcpA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.78A 5zcpN-1j6xA:
undetectable		 5zcpN-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.76A 5zcqA-1j6xA:
undetectable		 5zcqA-1j6xA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1j6x AUTOINDUCER-2
PRODUCTION PROTEIN
LUXS
(Helicobacter
pylori) 		3 / 3 HIS A  59
HIS A 128
HIS A  55
 ZN  A 161 (-3.4A)
ZN  A 161 ( 4.9A)
ZN  A 161 (-3.2A)
 0.77A 5zcqN-1j6xA:
undetectable		 5zcqN-1j6xA:
12.99