SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A 113
ASP A 108
ALA A  10
SER A  11
SER A 104
 None
 0.98A 1kiaD-1j6yA:
undetectable		 1kiaD-1j6yA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A 113
ASP A 108
ALA A  10
SER A  11
SER A 104
 None
 1.00A 1nbhC-1j6yA:
undetectable		 1nbhC-1j6yA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A 113
ASP A 108
ALA A  10
SER A  11
SER A 104
 None
 0.98A 1nbiA-1j6yA:
undetectable		 1nbiA-1j6yA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		5 / 12 VAL A 113
ASP A 108
ALA A  10
SER A  11
SER A 104
 None
 0.98A 1nbiB-1j6yA:
undetectable		 1nbiB-1j6yA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 116
GLY A  77
ALA A  64
PHE A  60
SER A 104
 None
 1.10A 3sudB-1j6yA:
undetectable		 3sudB-1j6yA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		4 / 5 SER A  72
ALA A  73
HIS A  12
LEU A  14
 None
 1.04A 5dzkb-1j6yA:
0.0
5dzkp-1j6yA:
undetectable		 5dzkb-1j6yA:
23.15
5dzkp-1j6yA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		4 / 6 SER A  72
ALA A  73
HIS A  12
LEU A  14
 None
 1.03A 5dzkB-1j6yA:
undetectable
5dzkP-1j6yA:
undetectable		 5dzkB-1j6yA:
23.15
5dzkP-1j6yA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		4 / 5 SER A  72
ALA A  73
HIS A  12
LEU A  14
 None
 1.03A 5dzkc-1j6yA:
0.0
5dzkq-1j6yA:
undetectable		 5dzkc-1j6yA:
23.15
5dzkq-1j6yA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1j6y PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Arabidopsis
thaliana) 		4 / 6 SER A  72
ALA A  73
HIS A  12
LEU A  14
 None
 1.08A 5dzkg-1j6yA:
undetectable
5dzku-1j6yA:
undetectable		 5dzkg-1j6yA:
23.15
5dzku-1j6yA:
6.06