SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JOM_A_FFOA161_0 (DIHYDROFOLATE REDUCTASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 11	ALA A 213 LEU A 299 ILE A 318 LEU A 320 THR A 211	None	1.29A	1jomA-1j71A: undetectable	1jomA-1j71A: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDR_B_MTXB170_1 (TELLUROMETHIONYL DIHYDROFOLATE REDUCTASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 10	ALA A 213 LEU A 299 ILE A 318 LEU A 320 THR A 211	None	1.37A	1tdrB-1j71A: undetectable	1tdrB-1j71A: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R5Q_B_1UNB900_2 (PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 11	ASP A 32 GLY A 34 ASP A 37 ILE A 82 ILE A 123	None	0.84A	2r5qB-1j71A: 7.2	2r5qB-1j71A: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2R5Q_D_1UND900_2 (PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 10	ASP A 32 GLY A 34 ASP A 37 ILE A 82 ILE A 123	None	0.84A	2r5qD-1j71A: 7.7	2r5qD-1j71A: 17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_C_C41C1328_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	6 / 12	ASP A 218 GLY A 220 VAL A 216 ASP A 32 GLY A 34 SER A 36	None	1.04A	2v0zC-1j71A: 36.4	2v0zC-1j71A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_C_C41C1328_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	7 / 12	VAL A 30 ASP A 32 GLY A 34 SER A 35 TYR A 84 ASP A 218 GLY A 220	None	0.56A	2v0zC-1j71A: 36.4	2v0zC-1j71A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_C_C41C1328_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 216 ASP A 218 GLY A 220 ASP A 32 GLY A 34	None	0.64A	2v0zC-1j71A: 36.4	2v0zC-1j71A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_O_C41O1327_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	6 / 12	ASP A 218 GLY A 220 VAL A 216 ASP A 32 GLY A 34 SER A 36	None	1.06A	2v0zO-1j71A: 35.7	2v0zO-1j71A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_O_C41O1327_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 30 ASP A 32 GLY A 34 ASP A 218 GLY A 220	None	0.46A	2v0zO-1j71A: 35.7	2v0zO-1j71A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0Z_O_C41O1327_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 216 ASP A 218 GLY A 220 ASP A 32 GLY A 34	None	0.63A	2v0zO-1j71A: 35.7	2v0zO-1j71A: 27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W9G_A_TOPA1159_1 (DIHYDROFOLATE REDUCTASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 10	LEU A 145 LEU A 38 VAL A 141 ILE A 31 PHE A 172	None	1.16A	2w9gA-1j71A: undetectable	2w9gA-1j71A: 19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZA_B_FOLB164_0 (DIHYDROFOLATE REDUCTASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 11	ALA A 213 LEU A 299 ILE A 318 LEU A 320 THR A 211	None	1.30A	2zzaB-1j71A: undetectable	2zzaB-1j71A: 17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D91_B_REMB350_1 (RENIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	ASP A 218 GLY A 220 VAL A 216 ASP A 32 SER A 36	None	0.88A	3d91B-1j71A: 36.0	3d91B-1j71A: 27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_C_TOPC200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 11	LEU A 304 ILE A 318 LEU A 320 PHE A 264 THR A 224	None	1.26A	3fl9C-1j71A: undetectable	3fl9C-1j71A: 16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_A_CELA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	TYR A 308 LEU A 184 SER A 329 ILE A 171 GLY A 173	None EOH A 573 ( 4.8A) None None None	1.04A	3kk6A-1j71A: undetectable	3kk6A-1j71A: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_B_CELB1701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	TYR A 308 LEU A 184 SER A 329 ILE A 171 GLY A 173	None EOH A 573 ( 4.8A) None None None	1.01A	3kk6B-1j71A: 0.0	3kk6B-1j71A: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P73_A_ACTA275_0 (MHC RFP-Y CLASS I ALPHA CHAIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	3 / 3	ILE A 298 VAL A 216 ARG A 196	None	0.74A	3p73A-1j71A: 0.0	3p73A-1j71A: 20.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PRS_A_RITA1001_2 (ENDOTHIAPEPSIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	7 / 12	ASP A 32 GLY A 34 ASP A 120 ASP A 218 THR A 221 TYR A 225 ILE A 298	None None None None EOH A 575 ( 4.4A) EOH A 575 ( 4.0A) None	0.55A	3prsA-1j71A: 36.5	3prsA-1j71A: 30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PRS_A_RITA1001_2 (ENDOTHIAPEPSIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ASP A 32 GLY A 34 GLY A 85 ASP A 86 ASP A 218 THR A 221 TYR A 225 ILE A 298	None None EOH A 575 (-4.0A) None None EOH A 575 ( 4.4A) EOH A 575 ( 4.0A) None	0.42A	3prsA-1j71A: 36.5	3prsA-1j71A: 30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PWW_A_ROCA1001_1 (ENDOTHIAPEPSIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	ASP A 32 GLY A 85 THR A 221 TYR A 225 ILE A 298	None EOH A 575 (-4.0A) EOH A 575 ( 4.4A) EOH A 575 ( 4.0A) None	0.34A	3pwwA-1j71A: 36.4	3pwwA-1j71A: 30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PWW_A_ROCA1001_2 (ENDOTHIAPEPSIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	6 / 8	GLY A 34 SER A 35 ILE A 82 TYR A 84 ASP A 86 THR A 222	None	0.55A	3pwwA-1j71A: 36.3	3pwwA-1j71A: 30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PWW_A_ROCA1001_2 (ENDOTHIAPEPSIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	6 / 8	GLY A 34 SER A 35 ILE A 82 TYR A 84 ASP A 218 THR A 222	None	0.22A	3pwwA-1j71A: 36.3	3pwwA-1j71A: 30.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q70_A_RITA2001_1 (CANDIDAPEPSIN-2)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ASP A 32 GLY A 34 GLY A 85 GLU A 194 ASP A 218 THR A 221 TYR A 225 ILE A 298	None None EOH A 575 (-4.0A) None None EOH A 575 ( 4.4A) EOH A 575 ( 4.0A) None	0.49A	3q70A-1j71A: 50.5	3q70A-1j71A: 62.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q70_A_RITA2001_1 (CANDIDAPEPSIN-2)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ILE A 123 ASP A 32 GLY A 34 GLY A 85 ASP A 218 THR A 221 TYR A 225 ILE A 298	None None None EOH A 575 (-4.0A) None EOH A 575 ( 4.4A) EOH A 575 ( 4.0A) None	1.12A	3q70A-1j71A: 50.5	3q70A-1j71A: 62.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	4 / 6	SER A 35 ILE A 82 TYR A 84 THR A 222	None	0.18A	3q70A-1j71A: 50.5	3q70A-1j71A: 62.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R24_A_SAMA302_1 (2'-O-METHYL TRANSFERASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	3 / 3	TYR A 308 ASP A 2 ASP A 176	None	0.84A	3r24A-1j71A: undetectable	3r24A-1j71A: 22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RV5_A_DXCA91_0 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	3 / 3	PHE A 111 GLN A 148 PHE A 65	None	0.82A	3rv5A-1j71A: undetectable	3rv5A-1j71A: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SFU_A_RBVA601_1 (RNA POLYMERASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 9	SER A 89 THR A 117 THR A 116 GLY A 92 ASP A 79	None	1.49A	3sfuA-1j71A: undetectable	3sfuA-1j71A: 19.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_A_RITA401_1 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ASP A 32 GLY A 34 ILE A 82 GLY A 85 ASP A 86 ASP A 218 TYR A 225 ILE A 298	None None None EOH A 575 (-4.0A) None None EOH A 575 ( 4.0A) None	0.46A	3tneA-1j71A: 49.5	3tneA-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_A_RITA401_1 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	GLY A 34 ILE A 82 GLY A 85 ASP A 86 ASP A 120 ASP A 218 TYR A 225 ILE A 298	None None EOH A 575 (-4.0A) None None None EOH A 575 ( 4.0A) None	0.77A	3tneA-1j71A: 49.5	3tneA-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_A_RITA401_1 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ILE A 123 ASP A 32 GLY A 34 GLY A 85 ASP A 86 ASP A 218 TYR A 225 ILE A 298	None None None EOH A 575 (-4.0A) None None EOH A 575 ( 4.0A) None	1.16A	3tneA-1j71A: 49.5	3tneA-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_A_RITA401_1 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ILE A 123 GLY A 34 GLY A 85 ASP A 86 ASP A 120 ASP A 218 TYR A 225 ILE A 298	None None EOH A 575 (-4.0A) None None None EOH A 575 ( 4.0A) None	1.36A	3tneA-1j71A: 49.5	3tneA-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_A_RITA401_2 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	6 / 6	PRO A 12 SER A 35 TYR A 84 VAL A 119 THR A 221 THR A 222	None None None None EOH A 575 ( 4.4A) None	0.30A	3tneA-1j71A: 49.5	3tneA-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_B_RITB401_1 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ASP A 32 GLY A 34 ILE A 82 GLY A 85 ASP A 86 ASP A 120 ASP A 218 ILE A 298	None None None EOH A 575 (-4.0A) None None None None	0.72A	3tneB-1j71A: 49.5	3tneB-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_B_RITB401_1 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	8 / 12	ILE A 123 ASP A 32 GLY A 34 GLY A 85 ASP A 86 ASP A 120 ASP A 218 ILE A 298	None None None EOH A 575 (-4.0A) None None None None	1.38A	3tneB-1j71A: 49.5	3tneB-1j71A: 54.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TNE_B_RITB401_2 (SECRETED ASPARTIC PROTEASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	7 / 7	SER A 35 TYR A 84 VAL A 119 ILE A 123 THR A 221 THR A 222 TYR A 225	None None None None EOH A 575 ( 4.4A) None EOH A 575 ( 4.0A)	0.51A	3tneB-1j71A: 49.5	3tneB-1j71A: 54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TVX_B_PNXB902_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	4 / 7	ASN A 302 ILE A 291 PHE A 234 PHE A 262	None	1.25A	3tvxB-1j71A: undetectable	3tvxB-1j71A: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_1 (RNA-DIRECTED RNA POLYMERASE L)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	3 / 3	SER A 329 ASP A 312 ASP A 2	None EOH A 573 ( 4.5A) None	0.77A	4uckA-1j71A: undetectable	4uckA-1j71A: 23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_A_STRA604_1 (CYTOCHROME P450 21-HYDROXYLASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 29 ILE A 18 GLY A 100 VAL A 3 LEU A 145	None None None EOH A 572 ( 4.2A) None	0.87A	4y8wA-1j71A: undetectable	4y8wA-1j71A: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_B_STRB603_1 (CYTOCHROME P450 21-HYDROXYLASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 29 ILE A 18 GLY A 100 VAL A 3 LEU A 145	None None None EOH A 572 ( 4.2A) None	0.88A	4y8wB-1j71A: undetectable	4y8wB-1j71A: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_C_STRC603_1 (CYTOCHROME P450 21-HYDROXYLASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 29 ILE A 18 GLY A 100 VAL A 3 LEU A 145	None None None EOH A 572 ( 4.2A) None	0.87A	4y8wC-1j71A: 0.0	4y8wC-1j71A: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DL9_A_ACTA214_0 (LYSOZYME C)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	4 / 5	GLU A 10 ASP A 120 VAL A 30 ALA A 15	None	1.32A	5dl9A-1j71A: undetectable	5dl9A-1j71A: 17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HGC_A_HCYA501_1 (SERPIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 310 ALA A 155 THR A 5 LYS A 153 ILE A 151	EOH A 573 (-4.6A) None None None None	1.39A	5hgcA-1j71A: 0.0	5hgcA-1j71A: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HQA_A_ACRA705_2 (ALPHA-GLUCOSIDASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	4 / 8	ASN A 297 TRP A 242 PHE A 234 THR A 221	None None None EOH A 575 ( 4.4A)	1.45A	5hqaA-1j71A: undetectable	5hqaA-1j71A: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M50_B_TA1B502_1 (TUBULIN BETA-2B CHAIN)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	VAL A 114 ASP A 113 SER A 90 THR A 55 GLY A 63	None	1.44A	5m50B-1j71A: undetectable	5m50B-1j71A: 23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1805_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 9	ILE A 291 GLY A 290 LEU A 277 PHE A 264 ILE A 270	None	0.91A	5vkqC-1j71A: undetectable 5vkqD-1j71A: undetectable	5vkqC-1j71A: 11.41 5vkqD-1j71A: 11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNI_A_YMZA302_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 9	VAL A 197 GLY A 34 TYR A 311 GLU A 194 GLY A 220	None	1.35A	5zniA-1j71A: undetectable	5zniA-1j71A: 12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_N_PCFN606_0 (CYTOCHROME B)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 12	ALA A 112 TYR A 95 PHE A 65 VAL A 40 VAL A 29	None	1.18A	6hu9N-1j71A: 0.0	6hu9N-1j71A: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6I5Z_D_SAMD401_0 (O-METHYLTRANSFERASE 1)	1j71	ASPARTIC PROTEINASE (Candida tropicalis)	5 / 11	GLY A 220 GLY A 34 ASP A 218 VAL A 216 ASP A 86	None	1.11A	6i5zD-1j71A: undetectable	6i5zD-1j71A: 23.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JOM_A_FFOA161_0","DIHYDROFOLATE REDUCTASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ALA A 213;LEU A 299;ILE A 318;LEU A 320;THR A 211","None","1.29A","1jomA-1j71A:undetectable","1jomA-1j71A:18.63"],["1TDR_B_MTXB170_1","TELLUROMETHIONYL DIHYDROFOLATE REDUCTASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ALA A 213;LEU A 299;ILE A 318;LEU A 320;THR A 211","None","1.37A","1tdrB-1j71A:undetectable","1tdrB-1j71A:18.63"],["2R5Q_B_1UNB900_2","PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ASP A  32;GLY A  34;ASP A  37;ILE A  82;ILE A 123","None","0.84A","2r5qB-1j71A:7.2","2r5qB-1j71A:17.05"],["2R5Q_D_1UND900_2","PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ASP A  32;GLY A  34;ASP A  37;ILE A  82;ILE A 123","None","0.84A","2r5qD-1j71A:7.7","2r5qD-1j71A:17.05"],["2V0Z_C_C41C1328_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",6,"ASP A 218;GLY A 220;VAL A 216;ASP A  32;GLY A  34;SER A  36","None","1.04A","2v0zC-1j71A:36.4","2v0zC-1j71A:27.03"],["2V0Z_C_C41C1328_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",7,"VAL A  30;ASP A  32;GLY A  34;SER A  35;TYR A  84;ASP A 218;GLY A 220","None","0.56A","2v0zC-1j71A:36.4","2v0zC-1j71A:27.03"],["2V0Z_C_C41C1328_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A 216;ASP A 218;GLY A 220;ASP A  32;GLY A  34","None","0.64A","2v0zC-1j71A:36.4","2v0zC-1j71A:27.03"],["2V0Z_O_C41O1327_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",6,"ASP A 218;GLY A 220;VAL A 216;ASP A  32;GLY A  34;SER A  36","None","1.06A","2v0zO-1j71A:35.7","2v0zO-1j71A:27.03"],["2V0Z_O_C41O1327_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A  30;ASP A  32;GLY A  34;ASP A 218;GLY A 220","None","0.46A","2v0zO-1j71A:35.7","2v0zO-1j71A:27.03"],["2V0Z_O_C41O1327_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A 216;ASP A 218;GLY A 220;ASP A  32;GLY A  34","None","0.63A","2v0zO-1j71A:35.7","2v0zO-1j71A:27.03"],["2W9G_A_TOPA1159_1","DIHYDROFOLATE REDUCTASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"LEU A 145;LEU A  38;VAL A 141;ILE A  31;PHE A 172","None","1.16A","2w9gA-1j71A:undetectable","2w9gA-1j71A:19.47"],["2ZZA_B_FOLB164_0","DIHYDROFOLATE REDUCTASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ALA A 213;LEU A 299;ILE A 318;LEU A 320;THR A 211","None","1.30A","2zzaB-1j71A:undetectable","2zzaB-1j71A:17.51"],["3D91_B_REMB350_1","RENIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ASP A 218;GLY A 220;VAL A 216;ASP A  32;SER A  36","None","0.88A","3d91B-1j71A:36.0","3d91B-1j71A:27.42"],["3FL9_C_TOPC200_1","DIHYDROFOLATE REDUCTASE (DHFR)","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"LEU A 304;ILE A 318;LEU A 320;PHE A 264;THR A 224","None","1.26A","3fl9C-1j71A:undetectable","3fl9C-1j71A:16.77"],["3KK6_A_CELA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"TYR A 308;LEU A 184;SER A 329;ILE A 171;GLY A 173","None;EOH A 573 ( 4.8A);None;None;None","1.04A","3kk6A-1j71A:undetectable","3kk6A-1j71A:19.33"],["3KK6_B_CELB1701_1","PROSTAGLANDIN G\/H SYNTHASE 1","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"TYR A 308;LEU A 184;SER A 329;ILE A 171;GLY A 173","None;EOH A 573 ( 4.8A);None;None;None","1.01A","3kk6B-1j71A:0.0","3kk6B-1j71A:19.33"],["3P73_A_ACTA275_0","MHC RFP-Y CLASS I ALPHA CHAIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",3,"ILE A 298;VAL A 216;ARG A 196","None","0.74A","3p73A-1j71A:0.0","3p73A-1j71A:20.99"],["3PRS_A_RITA1001_2","ENDOTHIAPEPSIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",7,"ASP A  32;GLY A  34;ASP A 120;ASP A 218;THR A 221;TYR A 225;ILE A 298","None;None;None;None;EOH A 575 ( 4.4A);EOH A 575 ( 4.0A);None","0.55A","3prsA-1j71A:36.5","3prsA-1j71A:30.88"],["3PRS_A_RITA1001_2","ENDOTHIAPEPSIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ASP A  32;GLY A  34;GLY A  85;ASP A  86;ASP A 218;THR A 221;TYR A 225;ILE A 298","None;None;EOH A 575 (-4.0A);None;None;EOH A 575 ( 4.4A);EOH A 575 ( 4.0A);None","0.42A","3prsA-1j71A:36.5","3prsA-1j71A:30.88"],["3PWW_A_ROCA1001_1","ENDOTHIAPEPSIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ASP A  32;GLY A  85;THR A 221;TYR A 225;ILE A 298","None;EOH A 575 (-4.0A);EOH A 575 ( 4.4A);EOH A 575 ( 4.0A);None","0.34A","3pwwA-1j71A:36.4","3pwwA-1j71A:30.88"],["3PWW_A_ROCA1001_2","ENDOTHIAPEPSIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",6,"GLY A  34;SER A  35;ILE A  82;TYR A  84;ASP A  86;THR A 222","None","0.55A","3pwwA-1j71A:36.3","3pwwA-1j71A:30.88"],["3PWW_A_ROCA1001_2","ENDOTHIAPEPSIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",6,"GLY A  34;SER A  35;ILE A  82;TYR A  84;ASP A 218;THR A 222","None","0.22A","3pwwA-1j71A:36.3","3pwwA-1j71A:30.88"],["3Q70_A_RITA2001_1","CANDIDAPEPSIN-2","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ASP A  32;GLY A  34;GLY A  85;GLU A 194;ASP A 218;THR A 221;TYR A 225;ILE A 298","None;None;EOH A 575 (-4.0A);None;None;EOH A 575 ( 4.4A);EOH A 575 ( 4.0A);None","0.49A","3q70A-1j71A:50.5","3q70A-1j71A:62.57"],["3Q70_A_RITA2001_1","CANDIDAPEPSIN-2","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ILE A 123;ASP A  32;GLY A  34;GLY A  85;ASP A 218;THR A 221;TYR A 225;ILE A 298","None;None;None;EOH A 575 (-4.0A);None;EOH A 575 ( 4.4A);EOH A 575 ( 4.0A);None","1.12A","3q70A-1j71A:50.5","3q70A-1j71A:62.57"],["3Q70_A_RITA2001_2","CANDIDAPEPSIN-2","1j71","ASPARTIC PROTEINASE","Candida tropicalis",4,"SER A  35;ILE A  82;TYR A  84;THR A 222","None","0.18A","3q70A-1j71A:50.5","3q70A-1j71A:62.57"],["3R24_A_SAMA302_1","2'-O-METHYL TRANSFERASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",3,"TYR A 308;ASP A   2;ASP A 176","None","0.84A","3r24A-1j71A:undetectable","3r24A-1j71A:22.77"],["3RV5_A_DXCA91_0","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1j71","ASPARTIC PROTEINASE","Candida tropicalis",3,"PHE A 111;GLN A 148;PHE A  65","None","0.82A","3rv5A-1j71A:undetectable","3rv5A-1j71A:15.85"],["3SFU_A_RBVA601_1","RNA POLYMERASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"SER A  89;THR A 117;THR A 116;GLY A  92;ASP A  79","None","1.49A","3sfuA-1j71A:undetectable","3sfuA-1j71A:19.77"],["3TNE_A_RITA401_1","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ASP A  32;GLY A  34;ILE A  82;GLY A  85;ASP A  86;ASP A 218;TYR A 225;ILE A 298","None;None;None;EOH A 575 (-4.0A);None;None;EOH A 575 ( 4.0A);None","0.46A","3tneA-1j71A:49.5","3tneA-1j71A:54.62"],["3TNE_A_RITA401_1","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"GLY A  34;ILE A  82;GLY A  85;ASP A  86;ASP A 120;ASP A 218;TYR A 225;ILE A 298","None;None;EOH A 575 (-4.0A);None;None;None;EOH A 575 ( 4.0A);None","0.77A","3tneA-1j71A:49.5","3tneA-1j71A:54.62"],["3TNE_A_RITA401_1","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ILE A 123;ASP A  32;GLY A  34;GLY A  85;ASP A  86;ASP A 218;TYR A 225;ILE A 298","None;None;None;EOH A 575 (-4.0A);None;None;EOH A 575 ( 4.0A);None","1.16A","3tneA-1j71A:49.5","3tneA-1j71A:54.62"],["3TNE_A_RITA401_1","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ILE A 123;GLY A  34;GLY A  85;ASP A  86;ASP A 120;ASP A 218;TYR A 225;ILE A 298","None;None;EOH A 575 (-4.0A);None;None;None;EOH A 575 ( 4.0A);None","1.36A","3tneA-1j71A:49.5","3tneA-1j71A:54.62"],["3TNE_A_RITA401_2","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",6,"PRO A  12;SER A  35;TYR A  84;VAL A 119;THR A 221;THR A 222","None;None;None;None;EOH A 575 ( 4.4A);None","0.30A","3tneA-1j71A:49.5","3tneA-1j71A:54.62"],["3TNE_B_RITB401_1","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ASP A  32;GLY A  34;ILE A  82;GLY A  85;ASP A  86;ASP A 120;ASP A 218;ILE A 298","None;None;None;EOH A 575 (-4.0A);None;None;None;None","0.72A","3tneB-1j71A:49.5","3tneB-1j71A:54.62"],["3TNE_B_RITB401_1","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",8,"ILE A 123;ASP A  32;GLY A  34;GLY A  85;ASP A  86;ASP A 120;ASP A 218;ILE A 298","None;None;None;EOH A 575 (-4.0A);None;None;None;None","1.38A","3tneB-1j71A:49.5","3tneB-1j71A:54.62"],["3TNE_B_RITB401_2","SECRETED ASPARTIC PROTEASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",7,"SER A  35;TYR A  84;VAL A 119;ILE A 123;THR A 221;THR A 222;TYR A 225","None;None;None;None;EOH A 575 ( 4.4A);None;EOH A 575 ( 4.0A)","0.51A","3tneB-1j71A:49.5","3tneB-1j71A:54.62"],["3TVX_B_PNXB902_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A","1j71","ASPARTIC PROTEINASE","Candida tropicalis",4,"ASN A 302;ILE A 291;PHE A 234;PHE A 262","None","1.25A","3tvxB-1j71A:undetectable","3tvxB-1j71A:21.01"],["4UCK_A_SAMA2409_1","RNA-DIRECTED RNA POLYMERASE L","1j71","ASPARTIC PROTEINASE","Candida tropicalis",3,"SER A 329;ASP A 312;ASP A   2","None;EOH A 573 ( 4.5A);None","0.77A","4uckA-1j71A:undetectable","4uckA-1j71A:23.13"],["4Y8W_A_STRA604_1","CYTOCHROME P450 21-HYDROXYLASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A  29;ILE A  18;GLY A 100;VAL A   3;LEU A 145","None;None;None;EOH A 572 ( 4.2A);None","0.87A","4y8wA-1j71A:undetectable","4y8wA-1j71A:18.26"],["4Y8W_B_STRB603_1","CYTOCHROME P450 21-HYDROXYLASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A  29;ILE A  18;GLY A 100;VAL A   3;LEU A 145","None;None;None;EOH A 572 ( 4.2A);None","0.88A","4y8wB-1j71A:undetectable","4y8wB-1j71A:18.26"],["4Y8W_C_STRC603_1","CYTOCHROME P450 21-HYDROXYLASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A  29;ILE A  18;GLY A 100;VAL A   3;LEU A 145","None;None;None;EOH A 572 ( 4.2A);None","0.87A","4y8wC-1j71A:0.0","4y8wC-1j71A:18.26"],["5DL9_A_ACTA214_0","LYSOZYME C","1j71","ASPARTIC PROTEINASE","Candida tropicalis",4,"GLU A  10;ASP A 120;VAL A  30;ALA A  15","None","1.32A","5dl9A-1j71A:undetectable","5dl9A-1j71A:17.07"],["5HGC_A_HCYA501_1","SERPIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A 310;ALA A 155;THR A   5;LYS A 153;ILE A 151","EOH A 573 (-4.6A);None;None;None;None","1.39A","5hgcA-1j71A:0.0","5hgcA-1j71A:21.51"],["5HQA_A_ACRA705_2","ALPHA-GLUCOSIDASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",4,"ASN A 297;TRP A 242;PHE A 234;THR A 221","None;None;None;EOH A 575 ( 4.4A)","1.45A","5hqaA-1j71A:undetectable","5hqaA-1j71A:20.45"],["5M50_B_TA1B502_1","TUBULIN BETA-2B CHAIN","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A 114;ASP A 113;SER A  90;THR A  55;GLY A  63","None","1.44A","5m50B-1j71A:undetectable","5m50B-1j71A:23.94"],["5VKQ_C_PCFC1805_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ILE A 291;GLY A 290;LEU A 277;PHE A 264;ILE A 270","None","0.91A","5vkqC-1j71A:undetectable;5vkqD-1j71A:undetectable","5vkqC-1j71A:11.41;5vkqD-1j71A:11.41"],["5ZNI_A_YMZA302_0","PURINE NUCLEOSIDE PHOSPHORYLASE","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"VAL A 197;GLY A  34;TYR A 311;GLU A 194;GLY A 220","None","1.35A","5zniA-1j71A:undetectable","5zniA-1j71A:12.11"],["6HU9_N_PCFN606_0","CYTOCHROME B","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"ALA A 112;TYR A  95;PHE A  65;VAL A  40;VAL A  29","None","1.18A","6hu9N-1j71A:0.0","6hu9N-1j71A:23.90"],["6I5Z_D_SAMD401_0","O-METHYLTRANSFERASE 1","1j71","ASPARTIC PROTEINASE","Candida tropicalis",5,"GLY A 220;GLY A  34;ASP A 218;VAL A 216;ASP A  86","None","1.11A","6i5zD-1j71A:undetectable","6i5zD-1j71A:23.26"]]