SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1j77 HEMO
(Neisseria
meningitidis) 		3 / 3 PHE A 183
TRP A 110
GLU A 102
 None
 0.99A 1mogA-1j77A:
undetectable		 1mogA-1j77A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 1j77 HEMO
(Neisseria
meningitidis) 		4 / 8 ASP A  87
LEU A  46
GLY A  89
TYR A 133
 None
 0.90A 1rmtC-1j77A:
undetectable		 1rmtC-1j77A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 1j77 HEMO
(Neisseria
meningitidis) 		3 / 3 MET A 205
VAL A  33
GLU A 199
 None
 0.88A 2x9gA-1j77A:
undetectable		 2x9gA-1j77A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1j77 HEMO
(Neisseria
meningitidis) 		3 / 3 ALA A  55
VAL A  81
TYR A  78
 None
 0.62A 5zmqH-1j77A:
undetectable		 5zmqH-1j77A:
24.29