SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CWK_A_REAA300_1 (CELLULAR RETINOIC ACID-BINDING PROTEIN 2)	1j7g	D-TYROSYL-TRNA(TYR) DEACYLASE (Haemophilus influenzae)	5 / 12	PHE A 109 LEU A 31 LEU A 81 ALA A 3 VAL A 66	None	1.25A	3cwkA-1j7gA: undetectable	3cwkA-1j7gA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PBH_A_BEZA401_0 (TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT, PUTATIVE)	1j7g	D-TYROSYL-TRNA(TYR) DEACYLASE (Haemophilus influenzae)	5 / 12	ILE A 23 ALA A 69 LEU A 73 LEU A 117 PHE A 55	None	1.36A	4pbhA-1j7gA: undetectable	4pbhA-1j7gA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HHJ_A_GLYA403_0 (RETRON-TYPE REVERSE TRANSCRIPTASE)	1j7g	D-TYROSYL-TRNA(TYR) DEACYLASE (Haemophilus influenzae)	4 / 4	LEU A 45 LEU A 31 GLY A 32 GLU A 34	None	1.16A	5hhjA-1j7gA: 0.0	5hhjA-1j7gA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TUD_D_ERMD1201_2 (5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA)	1j7g	D-TYROSYL-TRNA(TYR) DEACYLASE (Haemophilus influenzae)	5 / 6	LEU A 117 VAL A 119 THR A 121 LEU A 50 LEU A 142	None	1.12A	5tudD-1j7gA: undetectable	5tudD-1j7gA: 17.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CWK_A_REAA300_1","CELLULAR RETINOIC ACID-BINDING PROTEIN 2","1j7g","D-TYROSYL-TRNA(TYR) DEACYLASE","Haemophilus influenzae",5,"PHE A 109;LEU A  31;LEU A  81;ALA A   3;VAL A  66","None","1.25A","3cwkA-1j7gA:undetectable","3cwkA-1j7gA:22.15"],["4PBH_A_BEZA401_0","TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT, PUTATIVE","1j7g","D-TYROSYL-TRNA(TYR) DEACYLASE","Haemophilus influenzae",5,"ILE A  23;ALA A  69;LEU A  73;LEU A 117;PHE A  55","None","1.36A","4pbhA-1j7gA:undetectable","4pbhA-1j7gA:18.56"],["5HHJ_A_GLYA403_0","RETRON-TYPE REVERSE TRANSCRIPTASE","1j7g","D-TYROSYL-TRNA(TYR) DEACYLASE","Haemophilus influenzae",4,"LEU A  45;LEU A  31;GLY A  32;GLU A  34","None","1.16A","5hhjA-1j7gA:0.0","5hhjA-1j7gA:22.06"],["5TUD_D_ERMD1201_2","5-HYDROXYTRYPTAMINE RECEPTOR 2B,SOLUBLE CYTOCHROME B562 CHIMERA","1j7g","D-TYROSYL-TRNA(TYR) DEACYLASE","Haemophilus influenzae",5,"LEU A 117;VAL A 119;THR A 121;LEU A  50;LEU A 142","None","1.12A","5tudD-1j7gA:undetectable","5tudD-1j7gA:17.83"]]