SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_B_CHDB504_0 (FERROCHELATASE)	1j7j	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Salmonella enterica)	4 / 6	MET A 36 ILE A 25 ARG A 28 PRO A 120	None	1.24A	2qd3B-1j7jA: 0.0	2qd3B-1j7jA: 20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS6_B_EPAB1_2 (PROSTAGLANDIN G/H SYNTHASE 2)	1j7j	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Salmonella enterica)	4 / 7	VAL A 39 VAL A 95 LEU A 123 SER A 122	None	0.77A	3hs6B-1j7jA: undetectable	3hs6B-1j7jA: 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_B_CVIB301_0 (PUTATIVE REGULATORY PROTEIN)	1j7j	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Salmonella enterica)	5 / 12	LEU A 86 THR A 107 ILE A 90 LEU A 41 LEU A 123	None	1.38A	3vw1B-1j7jA: 0.0	3vw1B-1j7jA: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5SXT_B_NIZB808_1 (CATALASE-PEROXIDASE)	1j7j	HYPOXANTHINE PHOSPHORIBOSYLTRANSF ERASE (Salmonella enterica)	4 / 8	ARG A 112 VAL A 139 GLY A 116 LEU A 123	None	0.98A	5sxtB-1j7jA: undetectable	5sxtB-1j7jA: 13.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QD3_B_CHDB504_0","FERROCHELATASE","1j7j","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Salmonella enterica",4,"MET A  36;ILE A  25;ARG A  28;PRO A 120","None","1.24A","2qd3B-1j7jA:0.0","2qd3B-1j7jA:20.51"],["3HS6_B_EPAB1_2","PROSTAGLANDIN G\/H SYNTHASE 2","1j7j","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Salmonella enterica",4,"VAL A  39;VAL A  95;LEU A 123;SER A 122","None","0.77A","3hs6B-1j7jA:undetectable","3hs6B-1j7jA:14.75"],["3VW1_B_CVIB301_0","PUTATIVE REGULATORY PROTEIN","1j7j","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Salmonella enterica",5,"LEU A  86;THR A 107;ILE A  90;LEU A  41;LEU A 123","None","1.38A","3vw1B-1j7jA:0.0","3vw1B-1j7jA:21.26"],["5SXT_B_NIZB808_1","CATALASE-PEROXIDASE","1j7j","HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE","Salmonella enterica",4,"ARG A 112;VAL A 139;GLY A 116;LEU A 123","None","0.98A","5sxtB-1j7jA:undetectable","5sxtB-1j7jA:13.54"]]