SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1j7x INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN
(Xenopus
laevis) 		4 / 5 ILE A  80
PHE A 100
PHE A 114
ILE A 123
 None
 1.13A 2hjhA-1j7xA:
undetectable		 2hjhA-1j7xA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1j7x INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN
(Xenopus
laevis) 		5 / 10 LEU A  30
LEU A  33
LEU A  51
ILE A  26
VAL A 259
 None
 1.41A 4mk4A-1j7xA:
1.0		 4mk4A-1j7xA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1j7x INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN
(Xenopus
laevis) 		5 / 12 ALA A 158
THR A 214
GLY A 153
SER A 156
GLU A 220
 None
 1.40A 5hfjG-1j7xA:
undetectable		 5hfjG-1j7xA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 1j7x INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN
(Xenopus
laevis) 		5 / 12 PHE A 166
TYR A 200
ILE A 104
GLY A 110
ILE A 138
 None
 1.18A 5ifuA-1j7xA:
undetectable		 5ifuA-1j7xA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 1j7x INTERPHOTORECEPTOR
RETINOID-BINDING
PROTEIN
(Xenopus
laevis) 		4 / 7 TYR A 207
ILE A 145
ILE A 146
ILE A 138
 None
 0.93A 5murB-1j7xA:
undetectable		 5murB-1j7xA:
17.08