SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		3 / 3 THR A1118
THR A1156
PRO A1117
 None
 0.83A 1dscC-1j83A:
undetectable		 1dscC-1j83A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		4 / 6 LEU A1110
MET A1112
LEU A1161
MET A1186
 None
 1.25A 2kuhA-1j83A:
undetectable		 2kuhA-1j83A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		4 / 8 ILE A1197
ILE A1060
ASN A1121
VAL A1122
 None
 0.58A 2nniA-1j83A:
undetectable		 2nniA-1j83A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 12 ILE A1071
ILE A1163
MET A1112
PHE A1149
VAL A1120
 None
 1.01A 2ygqA-1j83A:
0.2		 2ygqA-1j83A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		4 / 7 LEU A1069
VAL A1051
LEU A1074
LEU A1110
 None
 0.82A 3g8iA-1j83A:
undetectable		 3g8iA-1j83A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		3 / 3 ASP A1040
ASN A1067
SER A1035
 None
 0.92A 3lslA-1j83A:
undetectable
3lslD-1j83A:
undetectable		 3lslA-1j83A:
18.60
3lslD-1j83A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		3 / 3 SER A1035
ASP A1040
ASN A1067
 None
 0.99A 3lslA-1j83A:
0.0
3lslD-1j83A:
0.0		 3lslA-1j83A:
18.60
3lslD-1j83A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 10 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.47A 3uf8A-1j83A:
undetectable		 3uf8A-1j83A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		4 / 5 HIS A1133
SER A1130
SER A1181
VAL A1183
 None
 1.46A 4a99D-1j83A:
undetectable		 4a99D-1j83A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 11 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.43A 4dz2A-1j83A:
undetectable
4dz2B-1j83A:
undetectable		 4dz2A-1j83A:
18.89
4dz2B-1j83A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 10 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.45A 4dz3B-1j83A:
undetectable		 4dz3B-1j83A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 10 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.48A 4laxA-1j83A:
undetectable		 4laxA-1j83A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 12 GLY A1136
PHE A1041
GLY A1048
PHE A1189
MET A1186
 None
 1.24A 4zdyA-1j83A:
undetectable		 4zdyA-1j83A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 11 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.39A 5hwcA-1j83A:
undetectable		 5hwcA-1j83A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 10 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.45A 6mkeC-1j83A:
undetectable		 6mkeC-1j83A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1j83 ENDO-1,4-BETA
GLUCANASE ENGF
(Clostridium
cellulovorans) 		5 / 10 ASP A1113
PHE A1149
VAL A1122
ILE A1124
ILE A1202
 None
 1.44A 6mkeD-1j83A:
undetectable		 6mkeD-1j83A:
15.56