SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT
(Homo
sapiens) 		4 / 7 VAL A   7
SER A  76
LEU A  53
PHE A  40
 None
 0.80A 2f78A-1j89A:
undetectable		 2f78A-1j89A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT
(Homo
sapiens) 		4 / 7 VAL A   7
SER A  76
LEU A  53
PHE A  40
 None
 0.89A 2f78B-1j89A:
undetectable		 2f78B-1j89A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT
(Homo
sapiens) 		4 / 6 VAL A   7
SER A  76
LEU A  53
PHE A  40
 None
 0.95A 2f8dA-1j89A:
undetectable		 2f8dA-1j89A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT
(Homo
sapiens) 		3 / 3 SER A 137
HIS A 108
ASP A 114
 None
 0.80A 2wa2B-1j89A:
undetectable		 2wa2B-1j89A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT
(Homo
sapiens) 		5 / 11 GLY A  19
ALA A  58
ASP A  62
PRO A  11
ILE A  16
 None
 0.90A 3ektC-1j89A:
undetectable		 3ektC-1j89A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 1j89 HIGH AFFINITY
IMMUNOGLOBULIN
EPSILON RECEPTOR
ALPHA-SUBUNIT
(Homo
sapiens) 		5 / 12 ARG A 106
ASP A  62
ILE A  55
PRO A  11
ILE A  16
 NAG  A 335 (-4.1A)
None
None
None
None
 1.14A 3nu5B-1j89A:
undetectable		 3nu5B-1j89A:
20.34