SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 7 ARG A 161
ALA A  37
VAL A   5
VAL A  39
 None
 0.81A 3o14A-1j8sA:
0.0		 3o14A-1j8sA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 5 SER A 165
ILE A   4
TYR A 166
GLY A  46
 None
 0.97A 3uboB-1j8sA:
undetectable		 3uboB-1j8sA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 7 TYR A   7
ASP A  11
LEU A   9
GLY A  10
 None
 0.90A 4iqqA-1j8sA:
undetectable		 4iqqA-1j8sA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 7 TYR A   7
ASP A  11
LEU A   9
GLY A  10
 None
 0.89A 4iqqB-1j8sA:
0.0		 4iqqB-1j8sA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 7 TYR A   7
ASP A  11
LEU A   9
GLY A  10
 None
 0.83A 4iqqC-1j8sA:
0.0		 4iqqC-1j8sA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 8 TYR A   7
ASP A  11
LEU A   9
GLY A  10
 None
 0.88A 4iqqD-1j8sA:
undetectable		 4iqqD-1j8sA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		5 / 12 ASN A   3
GLY A 115
ALA A  50
PHE A 163
TYR A   7
 None
 1.10A 4xt8A-1j8sA:
undetectable		 4xt8A-1j8sA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		3 / 3 THR A  72
PRO A  26
ARG A  25
 None
 0.74A 5nd7B-1j8sA:
undetectable		 5nd7B-1j8sA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 1j8s PYELONEPHRITIC
ADHESIN
(Escherichia
coli) 		4 / 6 TYR A   7
ASP A  11
LEU A   9
GLY A  10
 None
 0.92A 5nooC-1j8sA:
undetectable		 5nooC-1j8sA:
20.75