SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 10 GLU A 345
ALA A 347
LEU A 325
LEU A 300
GLU A 338
 None
 1.46A 1a29A-1j93A:
undetectable		 1a29A-1j93A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 GLY A 293
ILE A  78
GLY A  76
PRO A 247
ILE A 249
 None
 0.86A 1c6zA-1j93A:
undetectable		 1c6zA-1j93A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 10 ALA A 341
PHE A 343
ALA A 347
LEU A 350
LEU A 325
 None
 1.16A 2bxqA-1j93A:
undetectable		 2bxqA-1j93A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 LEU A 250
VAL A 267
VAL A 236
GLY A 151
LEU A 133
 None
 1.14A 2cbrA-1j93A:
undetectable		 2cbrA-1j93A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 8 LEU A 246
PRO A 122
VAL A 129
GLY A 130
 None
 0.88A 2po5B-1j93A:
undetectable		 2po5B-1j93A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 GLY A 298
LEU A 325
ASN A 339
THR A 314
PHE A 343
 None
 1.07A 2y7hC-1j93A:
undetectable		 2y7hC-1j93A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 TYR A 251
PHE A 343
LEU A 300
HIS A 329
SER A 271
 SO4  A 584 (-4.5A)
None
None
SO4  A 584 (-4.0A)
None
 1.23A 3apvA-1j93A:
undetectable		 3apvA-1j93A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 TYR A 251
PHE A 343
LEU A 300
HIS A 329
SER A 271
 SO4  A 584 (-4.5A)
None
None
SO4  A 584 (-4.0A)
None
 1.31A 3apvA-1j93A:
undetectable		 3apvA-1j93A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 PHE A 105
LEU A  84
GLY A 164
GLY A 163
PRO A 107
 None
 1.11A 3i5uA-1j93A:
undetectable		 3i5uA-1j93A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 8 GLY A 164
VAL A 103
ILE A  92
PHE A 190
 None
 0.80A 4fglD-1j93A:
undetectable		 4fglD-1j93A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 7 GLY A 164
VAL A 103
ILE A  92
PHE A 190
 None
 0.87A 4fglC-1j93A:
undetectable		 4fglC-1j93A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 11 GLY A  76
ILE A  78
GLY A 293
PHE A 343
PHE A 344
 None
 1.18A 4qoiA-1j93A:
undetectable
4qoiB-1j93A:
undetectable		 4qoiA-1j93A:
21.33
4qoiB-1j93A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 9 LEU A  79
SER A 204
THR A 134
LEU A 133
ILE A 135
 None
 1.23A 4ubsA-1j93A:
0.0		 4ubsA-1j93A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 6 LEU A 258
SER A 228
PRO A 230
PHE A 227
 None
 1.15A 5b8iA-1j93A:
undetectable		 5b8iA-1j93A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 ILE A 324
GLY A 293
ARG A 282
LEU A 262
PRO A 263
 None
 1.22A 5ergB-1j93A:
undetectable		 5ergB-1j93A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		3 / 3 TRP A  29
ILE A 249
SER A 271
 None
 1.02A 5gqbA-1j93A:
7.3		 5gqbA-1j93A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 LEU A 219
ALA A 216
ILE A  92
ILE A 172
LEU A  84
 None
 1.16A 5h8tA-1j93A:
undetectable		 5h8tA-1j93A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 6 PRO A 153
VAL A 150
VAL A 209
ILE A 235
 None
 0.91A 5pbeA-1j93A:
undetectable		 5pbeA-1j93A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		5 / 12 PRO A 263
ILE A 249
LEU A 262
VAL A 289
LEU A  15
 None
 1.25A 5tiwA-1j93A:
0.4		 5tiwA-1j93A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 6 PHE A 120
TYR A 128
LEU A  79
SER A  55
 None
 1.50A 6a7pB-1j93A:
undetectable		 6a7pB-1j93A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		4 / 7 GLY A 328
TRP A 274
ASP A 277
MET A 278
 None
 1.41A 6ag0A-1j93A:
10.8		 6ag0A-1j93A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1j93 UROPORPHYRINOGEN
DECARBOXYLASE
(Nicotiana
tabacum) 		3 / 3 GLY A 266
ASP A 268
ILE A 249
 None
 0.61A 6dgxB-1j93A:
undetectable		 6dgxB-1j93A:
14.04