SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1j9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1j9a OLIGORIBONUCLEASE
(Haemophilus
influenzae) 		4 / 6 ALA A  44
GLU A  45
LEU A 164
LEU A  49
 None
 1.00A 1mt1D-1j9aA:
0.0
1mt1E-1j9aA:
undetectable		 1mt1D-1j9aA:
23.53
1mt1E-1j9aA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1j9a OLIGORIBONUCLEASE
(Haemophilus
influenzae) 		3 / 3 LYS A 121
ARG A 117
LYS A  60
 None
 1.47A 3okxA-1j9aA:
undetectable		 3okxA-1j9aA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 1j9a OLIGORIBONUCLEASE
(Haemophilus
influenzae) 		4 / 8 LEU A  16
THR A  84
TYR A 122
PHE A 118
 None
 0.86A 4drjB-1j9aA:
undetectable		 4drjB-1j9aA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 1j9a OLIGORIBONUCLEASE
(Haemophilus
influenzae) 		5 / 12 PHE A 130
THR A  33
LEU A  93
LEU A  16
LEU A 119
 None
 1.38A 4qynB-1j9aA:
0.4		 4qynB-1j9aA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1j9a OLIGORIBONUCLEASE
(Haemophilus
influenzae) 		5 / 12 VAL A  51
LEU A  83
ALA A  87
ILE A  12
ILE A  31
 None
 1.20A 5hbsA-1j9aA:
undetectable		 5hbsA-1j9aA:
18.42