SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jae'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 HIS A  99
ASP A 185
LEU A 150
LEU A 153
GLY A 102
 None
 1.10A 1d4fD-1jaeA:
undetectable		 1d4fD-1jaeA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 TYR A  60
LEU A 150
LEU A 153
ASP A 185
ALA A 186
HIS A 286
ASP A 287
 None
 0.65A 1dedA-1jaeA:
28.6		 1dedA-1jaeA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		8 / 12 TYR A  60
LEU A 153
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.74A 1dedB-1jaeA:
30.4		 1dedB-1jaeA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 TYR A  60
GLN A  61
HIS A 189
HIS A 286
ASP A 287
 None
 1.12A 1eswA-1jaeA:
16.2		 1eswA-1jaeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 TYR A  60
GLN A  61
HIS A 286
ASP A 287
TRP A  56
 None
 0.98A 1eswA-1jaeA:
16.2		 1eswA-1jaeA:
20.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		9 / 12 TRP A  56
GLN A  61
HIS A  99
VAL A 151
GLY A 152
ALA A 186
GLU A 222
ILE A 224
ASP A 287
 None
 0.32A 1kxhA-1jaeA:
52.3		 1kxhA-1jaeA:
43.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 TRP A  56
HIS A  99
GLY A 102
GLU A 222
ASP A 287
 None
 1.14A 1kxhA-1jaeA:
52.3		 1kxhA-1jaeA:
43.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		3 / 3 TRP A  57
TYR A  60
LEU A 153
 None
 0.23A 1kxhA-1jaeA:
52.3		 1kxhA-1jaeA:
43.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 6 ASN A 266
TRP A 385
HIS A 315
GLY A 268
 None
 1.30A 1mxdA-1jaeA:
30.3		 1mxdA-1jaeA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		9 / 12 TRP A  56
TYR A  60
HIS A  99
ARG A 183
ASP A 185
LYS A 188
GLU A 222
HIS A 286
ASP A 287
 None
None
None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.65A 1mxdA-1jaeA:
30.3		 1mxdA-1jaeA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 GLU A 275
GLY A 238
PHE A 239
LEU A 195
ASN A 234
 None
 1.23A 1nw3A-1jaeA:
undetectable		 1nw3A-1jaeA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 7 HIS A 189
TYR A 236
LEU A 195
GLN A 221
 None
 1.12A 1qzrA-1jaeA:
0.0		 1qzrA-1jaeA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 7 HIS A 189
TYR A 236
LEU A 195
GLN A 221
 None
 1.10A 1qzrB-1jaeA:
0.0		 1qzrB-1jaeA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 9 SER A 396
PHE A 405
GLY A 461
ILE A 428
PHE A 373
 None
 1.18A 2dr6A-1jaeA:
0.0		 2dr6A-1jaeA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 ILE A  24
ALA A  25
ARG A  83
ILE A 348
HIS A 362
 None
 1.09A 2h77A-1jaeA:
0.0		 2h77A-1jaeA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		6 / 11 TYR A  60
GLN A  61
ASP A 185
HIS A 286
ASP A 287
TRP A  56
 None
 0.92A 2owcA-1jaeA:
15.8		 2owcA-1jaeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		6 / 11 TYR A  60
GLN A  61
ASP A 185
HIS A 286
ASP A 287
TRP A  56
 None
 0.91A 2owwA-1jaeA:
3.4		 2owwA-1jaeA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.62A 3aicA-1jaeA:
8.3		 3aicA-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		6 / 12 ARG A 183
ALA A 186
ASN A  98
GLU A 222
HIS A 286
ASP A 287
 CL  A 501 (-4.0A)
None
CA  A 500 (-3.1A)
None
None
None
 1.42A 3aicB-1jaeA:
3.9		 3aicB-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.61A 3aicB-1jaeA:
3.9		 3aicB-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
TYR A  60
 CL  A 501 (-4.0A)
None
None
None
None
None
None
 0.62A 3aicC-1jaeA:
8.9		 3aicC-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.65A 3aicD-1jaeA:
9.0		 3aicD-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.64A 3aicE-1jaeA:
9.0		 3aicE-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.64A 3aicF-1jaeA:
8.1		 3aicF-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.60A 3aicG-1jaeA:
9.0		 3aicG-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 LEU A 150
ARG A 183
ASP A 185
ALA A 186
GLU A 222
HIS A 286
ASP A 287
 None
CL  A 501 (-4.0A)
None
None
None
None
None
 0.68A 3aicH-1jaeA:
8.9		 3aicH-1jaeA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 VAL A 223
TYR A  65
ILE A 219
VAL A 163
TYR A 125
 None
None
PCA  A   1 ( 4.6A)
None
None
 1.25A 3g8iA-1jaeA:
0.0		 3g8iA-1jaeA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 LEU A 195
GLY A 238
ILE A 198
SER A 200
ARG A 216
 None
 1.30A 3gyqA-1jaeA:
4.3
3gyqB-1jaeA:
4.2		 3gyqA-1jaeA:
20.94
3gyqB-1jaeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		3 / 3 GLY A 341
PRO A 335
LEU A 343
 None
 0.64A 3hcpB-1jaeA:
0.0		 3hcpB-1jaeA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		3 / 3 ARG A 183
THR A  81
THR A  69
 CL  A 501 (-4.0A)
None
None
 0.74A 3k2hB-1jaeA:
undetectable		 3k2hB-1jaeA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 11 ASP A 284
ASN A 288
PHE A 328
PHE A 326
THR A 298
 None
 1.43A 3n23A-1jaeA:
undetectable		 3n23A-1jaeA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 8 ASP A 176
VAL A 179
ILE A 168
PRO A 217
 None
 0.76A 3nu9A-1jaeA:
undetectable		 3nu9A-1jaeA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 6 VAL A  89
VAL A 371
ILE A  13
ARG A  30
 None
 1.01A 3pyyA-1jaeA:
undetectable		 3pyyA-1jaeA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 ILE A 198
GLY A 201
ILE A 175
VAL A 179
ASN A  46
 None
 1.20A 4a81A-1jaeA:
undetectable		 4a81A-1jaeA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 6 ARG A 164
GLY A 165
ASP A 194
HIS A 131
 None
 1.22A 4lajA-1jaeA:
undetectable
4lajB-1jaeA:
undetectable		 4lajA-1jaeA:
18.35
4lajB-1jaeA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 ILE A  24
ALA A  25
ARG A  83
ILE A 348
HIS A 362
 None
 1.10A 4lnwA-1jaeA:
0.0		 4lnwA-1jaeA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 ILE A  24
ALA A  25
ARG A  83
ILE A 348
HIS A 362
 None
 1.10A 4lnxA-1jaeA:
undetectable		 4lnxA-1jaeA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 LEU A 251
ALA A 314
ALA A 404
ILE A 393
VAL A 462
 None
 1.11A 4nkxC-1jaeA:
undetectable		 4nkxC-1jaeA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 LEU A 251
ALA A 314
ALA A 404
ILE A 393
VAL A 462
 None
 1.09A 4nkxD-1jaeA:
undetectable		 4nkxD-1jaeA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		3 / 3 ARG A  54
TYR A  48
GLU A  58
 None
 0.70A 4zzbE-1jaeA:
undetectable		 4zzbE-1jaeA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 ARG A 183
ASP A 185
GLU A 222
HIS A 286
ASP A 287
 CL  A 501 (-4.0A)
None
None
None
None
 0.42A 5csyB-1jaeA:
5.0		 5csyB-1jaeA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 PHE A   6
VAL A 280
ALA A   4
ILE A  24
LEU A  32
 None
 1.13A 5hbsA-1jaeA:
undetectable		 5hbsA-1jaeA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		3 / 3 LYS A 440
GLN A 413
ASN A 412
 None
 0.95A 5l2tA-1jaeA:
undetectable		 5l2tA-1jaeA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		4 / 8 GLY A 110
ARG A  54
VAL A 106
TYR A  48
 None
 0.94A 5vlmA-1jaeA:
undetectable		 5vlmA-1jaeA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		8 / 12 TRP A  56
TYR A  60
HIS A  99
GLU A 229
ASP A 185
HIS A 189
HIS A 286
ASP A 287
 None
 1.09A 6ag0A-1jaeA:
29.4		 6ag0A-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		9 / 12 TRP A  56
TYR A  60
HIS A  99
LEU A 150
ASP A 185
LYS A 188
HIS A 189
HIS A 286
ASP A 287
 None
 0.70A 6ag0A-1jaeA:
29.4		 6ag0A-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		6 / 12 TRP A  56
TYR A  60
LEU A 153
ASP A 185
HIS A 286
ASP A 287
 None
 1.40A 6ag0A-1jaeA:
29.4		 6ag0A-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 TRP A  56
GLU A 229
ASP A 185
LYS A 188
HIS A 189
HIS A 286
ASP A 287
 None
 1.20A 6ag0C-1jaeA:
29.5		 6ag0C-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		6 / 12 TRP A  56
GLU A 229
TYR A 139
LYS A 188
HIS A 286
ASP A 287
 None
 1.42A 6ag0C-1jaeA:
29.5		 6ag0C-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		7 / 12 TRP A  56
LEU A 150
ASP A 185
LYS A 188
HIS A 189
HIS A 286
ASP A 287
 None
 0.68A 6ag0C-1jaeA:
29.5		 6ag0C-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 12 TRP A  56
LEU A 153
ASP A 185
HIS A 286
ASP A 287
 None
 1.39A 6ag0C-1jaeA:
29.5		 6ag0C-1jaeA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1jae ALPHA-AMYLASE
(Tenebrio
molitor) 		5 / 9 LEU A 195
SER A 196
PHE A 199
LEU A 202
VAL A 184
 None
 1.25A 6ftpA-1jaeA:
0.0
6ftpB-1jaeA:
undetectable		 6ftpA-1jaeA:
9.59
6ftpB-1jaeA:
7.13