SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
4 / 7 ILE B  90
PHE B  63
ILE B  80
PHE B  50
None
1.07A 2q6hA-1jb7B:
undetectable
2q6hA-1jb7B:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
4 / 7 ILE B  90
PHE B  63
ILE B  80
PHE B  50
None
1.08A 2qb4A-1jb7B:
undetectable
2qb4A-1jb7B:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
5 / 12 ILE B  88
PHE B  14
TYR B  18
PHE B 139
LEU B  97
None
1.10A 4j03A-1jb7B:
undetectable
4j03A-1jb7B:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
5 / 12 VAL B 100
SER B 102
THR B  19
ARG B 140
LEU B 138
None
1.44A 5m50B-1jb7B:
undetectable
5m50B-1jb7B:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
4 / 8 PHE B  14
PRO B 131
THR B 132
PRO B 135
None
1.15A 5x23A-1jb7B:
undetectable
5x23A-1jb7B:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
4 / 6 TYR B  47
LEU B 213
LYS B 223
GLU B 222
None
1.09A 5xooA-1jb7B:
0.0
5xooA-1jb7B:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)
1jb7 TELOMERE-BINDING
PROTEIN BETA SUBUNIT

(Sterkiella
nova)
4 / 8 PHE B 139
PHE B  22
VAL B 100
SER B 102
None
1.11A 6huoC-1jb7B:
undetectable
6huoD-1jb7B:
0.0
6huoC-1jb7B:
16.09
6huoD-1jb7B:
18.02