SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1jba PROTEIN (GUANYLATE
CYCLASE ACTIVATING
PROTEIN 2)
(Bos
taurus) 		5 / 9 VAL A 157
VAL A 171
GLY A 173
LEU A 117
TYR A 104
 None
 1.47A 1lwfA-1jbaA:
undetectable		 1lwfA-1jbaA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jba PROTEIN (GUANYLATE
CYCLASE ACTIVATING
PROTEIN 2)
(Bos
taurus) 		3 / 3 PRO A  52
ASP A  53
GLU A  55
 None
 0.78A 3v4tC-1jbaA:
undetectable		 3v4tC-1jbaA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1jba PROTEIN (GUANYLATE
CYCLASE ACTIVATING
PROTEIN 2)
(Bos
taurus) 		4 / 7 ASN A  13
GLU A   9
GLU A  11
GLU A  12
 None
 1.26A 4mj8C-1jbaA:
0.0		 4mj8C-1jbaA:
24.63