SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1jbg TRANSCRIPTION
ACTIVATOR OF
MULTIDRUG-EFFLUX
TRANSPORTER GENES
MTA
(Bacillus
subtilis) 		4 / 7 ARG A  76
LYS A  77
LEU A  80
GLN A  81
 None
 1.03A 2eijP-1jbgA:
undetectable
2eijW-1jbgA:
1.3		 2eijP-1jbgA:
15.85
2eijW-1jbgA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1jbg TRANSCRIPTION
ACTIVATOR OF
MULTIDRUG-EFFLUX
TRANSPORTER GENES
MTA
(Bacillus
subtilis) 		3 / 3 PHE A  74
PHE A  55
PHE A  60
 None
 0.83A 2od9A-1jbgA:
undetectable		 2od9A-1jbgA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1jbg TRANSCRIPTION
ACTIVATOR OF
MULTIDRUG-EFFLUX
TRANSPORTER GENES
MTA
(Bacillus
subtilis) 		3 / 3 PHE A  74
PHE A  55
PHE A  60
 None
 0.83A 2qqgA-1jbgA:
undetectable		 2qqgA-1jbgA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1jbg TRANSCRIPTION
ACTIVATOR OF
MULTIDRUG-EFFLUX
TRANSPORTER GENES
MTA
(Bacillus
subtilis) 		3 / 3 VAL A   8
SER A  12
LEU A  19
 None
 0.73A 3n8xA-1jbgA:
undetectable		 3n8xA-1jbgA:
11.75