SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		4 / 6 ARG A  95
GLY A 212
TYR A 216
TRP A 214
 None
 1.14A 1kf6M-1jc9A:
undetectable
1kf6N-1jc9A:
0.0		 1kf6M-1jc9A:
18.02
1kf6N-1jc9A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		5 / 12 GLY A 212
SER A 193
ILE A 240
HIS A 187
PHE A 184
 None
 1.15A 1ve3B-1jc9A:
undetectable		 1ve3B-1jc9A:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J1G_F_SC2F1290_1
(FICOLIN-2)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		6 / 10 SER A  60
ASP A  81
THR A  84
ARG A  94
GLU A 256
LYS A 258
 None
 1.15A 2j1gE-1jc9A:
35.5
2j1gF-1jc9A:
35.3		 2j1gE-1jc9A:
40.08
2j1gF-1jc9A:
40.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		3 / 3 ILE A  92
ILE A 162
LEU A 145
 None
 0.56A 2prgA-1jc9A:
undetectable		 2prgA-1jc9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		3 / 3 ARG A  94
THR A  90
VAL A  91
 None
 0.98A 2q64A-1jc9A:
0.0		 2q64A-1jc9A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ATT_A_ACTA1209_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		4 / 4 ASP A 151
ARG A 153
ASP A 147
GLU A 149
 None
 1.35A 3attA-1jc9A:
0.0		 3attA-1jc9A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		4 / 7 TYR A  79
VAL A  78
ILE A  65
GLU A 256
 None
 0.96A 4a97H-1jc9A:
undetectable		 4a97H-1jc9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		4 / 8 TYR A  79
VAL A  78
ILE A  65
GLU A 256
 None
 1.04A 4a97I-1jc9A:
undetectable		 4a97I-1jc9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		5 / 8 ILE A 195
ILE A  92
ILE A 141
ILE A 130
PHE A 192
 None
 1.41A 5hi2A-1jc9A:
undetectable		 5hi2A-1jc9A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		5 / 12 LEU A 227
GLY A 239
HIS A 233
SER A 193
ASP A 200
 None
None
None
None
CA  A 301 (-2.6A)
 1.23A 6bxlA-1jc9A:
undetectable		 6bxlA-1jc9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		3 / 3 LEU A 133
LEU A 125
ARG A 129
 None
 0.70A 6fgcA-1jc9A:
0.0		 6fgcA-1jc9A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		5 / 12 ASN A 225
ILE A  92
ILE A 162
PHE A 143
PHE A 184
 None
 1.45A 6j21A-1jc9A:
0.0		 6j21A-1jc9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		4 / 4 HIS A 220
LEU A 252
TYR A 250
GLY A 247
 NAG  A 270 (-3.7A)
None
None
None
 1.37A 6n91A-1jc9A:
undetectable		 6n91A-1jc9A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1jc9 TECHYLECTIN-5A
(Tachypleus
tridentatus) 		4 / 4 HIS A 220
LEU A 252
TYR A 250
GLY A 247
 NAG  A 270 (-3.7A)
None
None
None
 1.37A 6n91B-1jc9A:
0.0		 6n91B-1jc9A:
14.07