SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 9 TYR A  94
PHE A  90
VAL A  56
ILE A  60
PHE A  98
 None
 1.45A 1bkfA-1jd1A:
undetectable		 1bkfA-1jd1A:
23.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  20
ILE A  36
PRO A 114
GLU A 120
 None
 0.40A 1oniA-1jd1A:
22.4
1oniB-1jd1A:
23.1		 1oniA-1jd1A:
38.64
1oniB-1jd1A:
38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  20
ILE A  36
PRO A 114
GLU A 120
 None
 0.35A 1oniB-1jd1A:
23.1
1oniC-1jd1A:
23.0		 1oniB-1jd1A:
38.64
1oniC-1jd1A:
38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  20
ILE A  36
PRO A 114
GLU A 120
 None
 0.57A 1oniA-1jd1A:
22.4
1oniC-1jd1A:
23.0		 1oniA-1jd1A:
38.64
1oniC-1jd1A:
38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  20
ILE A  36
PRO A 114
GLU A 120
 None
 0.66A 1oniD-1jd1A:
22.7
1oniE-1jd1A:
22.8		 1oniD-1jd1A:
38.64
1oniE-1jd1A:
38.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  20
ILE A  36
PRO A 114
GLU A 120
 None
 0.39A 1oniG-1jd1A:
23.1
1oniI-1jd1A:
22.7		 1oniG-1jd1A:
38.64
1oniI-1jd1A:
38.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 SER A  70
ARG A 105
PRO A 103
VAL A  74
ILE A  60
 None
 1.44A 2tctA-1jd1A:
undetectable		 2tctA-1jd1A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 SER A  70
ARG A 105
PRO A 103
VAL A  74
ILE A  60
 None
 1.34A 2xpvA-1jd1A:
undetectable		 2xpvA-1jd1A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 TYR A  94
PHE A  90
VAL A  56
ILE A  60
PHE A  98
 None
 1.49A 3uf8A-1jd1A:
undetectable		 3uf8A-1jd1A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 9 VAL A  77
GLU A 120
VAL A  56
ILE A  60
ALA A 125
 None
 1.14A 4fwdA-1jd1A:
undetectable		 4fwdA-1jd1A:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1jd1 HYPOTHETICAL 13.9
KDA PROTEIN IN
FCY2-PET117
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 6 ASN A  62
GLU A  54
TYR A  97
LEU A  71
 None
 1.27A 4twdB-1jd1A:
undetectable
4twdC-1jd1A:
0.5		 4twdB-1jd1A:
18.66
4twdC-1jd1A:
18.66