SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jd3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		5 / 12 TYR A 164
GLY A 136
ALA A 135
GLY A 132
LEU A  11
 None
 1.07A 1fe2A-1jd3A:
undetectable		 1fe2A-1jd3A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		3 / 3 ARG A 140
ARG A  37
ARG A 126
 None
 1.08A 1l7fA-1jd3A:
undetectable		 1l7fA-1jd3A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		3 / 3 ARG A 140
ARG A  37
ARG A 126
 None
 1.07A 1l7hA-1jd3A:
undetectable		 1l7hA-1jd3A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		3 / 3 PRO A 162
LEU A 163
ARG A 140
 None
 0.88A 3aqiA-1jd3A:
undetectable		 3aqiA-1jd3A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		5 / 12 TYR A 164
GLY A 136
ALA A 135
GLY A 132
LEU A  11
 None
 0.92A 3hs6B-1jd3A:
0.0		 3hs6B-1jd3A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		3 / 3 ARG A 126
ASP A  26
GLN A  41
 None
 0.84A 3lcvB-1jd3A:
undetectable		 3lcvB-1jd3A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		5 / 12 TYR A 164
GLY A 136
ALA A 135
GLY A 132
LEU A  11
 None
 0.96A 4e1gA-1jd3A:
undetectable		 4e1gA-1jd3A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jd3 CHORISMATE LYASE
(Escherichia
coli) 		5 / 12 TYR A 164
GLY A 136
ALA A 135
GLY A 132
LEU A  11
 None
 0.96A 4e1gB-1jd3A:
undetectable		 4e1gB-1jd3A:
17.37