SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		3 / 3 ASP A   4
LEU A   5
HIS A 185
 None
 0.72A 1qknA-1jdiA:
0.0		 1qknA-1jdiA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 LEU A 167
GLY A 108
GLN A 109
ARG A 201
THR A 152
 None
 1.31A 2q7lA-1jdiA:
undetectable		 2q7lA-1jdiA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 6 ILE A 149
TRP A 176
LEU A 190
ILE A 126
 None
 1.02A 2q83B-1jdiA:
0.2		 2q83B-1jdiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 GLY A 146
ASN A 147
ILE A  93
LEU A  82
THR A  77
 None
 1.15A 3eeyB-1jdiA:
undetectable		 3eeyB-1jdiA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 GLY A 146
ASN A 147
ILE A  93
LEU A  82
THR A  77
 None
 1.17A 3eeyC-1jdiA:
undetectable		 3eeyC-1jdiA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 GLY A 146
ASN A 147
ILE A  93
LEU A  82
THR A  77
 None
 1.18A 3eeyD-1jdiA:
undetectable		 3eeyD-1jdiA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 4 LEU A 167
ALA A 194
VAL A 193
PRO A 112
 None
 1.13A 3gv1B-1jdiA:
0.0		 3gv1B-1jdiA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 4 PRO A  78
THR A  79
GLY A 172
THR A 102
 None
 1.13A 3ib1A-1jdiA:
undetectable		 3ib1A-1jdiA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 8 HIS A  95
ILE A  93
SER A  30
ILE A  41
 ZN  A 301 (-3.3A)
None
None
None
 1.05A 3sfeB-1jdiA:
0.0
3sfeC-1jdiA:
undetectable		 3sfeB-1jdiA:
19.06
3sfeC-1jdiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 5 HIS A 118
GLY A 124
TYR A 121
TYR A 219
 None
 1.43A 4ae1B-1jdiA:
undetectable		 4ae1B-1jdiA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 6 ALA A  53
LEU A  10
VAL A   9
ASP A   4
 None
 0.94A 4g24A-1jdiA:
undetectable		 4g24A-1jdiA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 LEU A 167
GLY A 108
GLN A 109
ARG A 201
THR A 152
 None
 1.35A 4hlwA-1jdiA:
undetectable		 4hlwA-1jdiA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		3 / 3 HIS A  80
TRP A 176
SER A  74
 None
 0.84A 4lrhD-1jdiA:
undetectable		 4lrhD-1jdiA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 6 LEU A   5
GLU A  11
VAL A 184
ALA A 183
 None
 1.09A 4nkvC-1jdiA:
0.0		 4nkvC-1jdiA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 LEU A 190
ALA A 101
THR A 145
VAL A  94
ALA A 175
 None
 1.00A 4x1iB-1jdiA:
undetectable		 4x1iB-1jdiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		5 / 12 LEU A 190
ALA A 101
THR A 145
VAL A  94
ALA A 175
 None
 1.02A 4x20B-1jdiA:
undetectable		 4x20B-1jdiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		3 / 3 PHE A  87
ILE A 149
ASP A  76
 None
None
ZN  A 301 ( 4.2A)
 0.76A 5cswA-1jdiA:
undetectable		 5cswA-1jdiA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		3 / 3 THR A 133
ASP A 134
ALA A 135
 None
 0.11A 5g5gB-1jdiA:
0.0		 5g5gB-1jdiA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		4 / 6 PHE A 174
SER A  75
HIS A 171
TYR A 141
 None
None
ZN  A 301 (-3.1A)
None
 1.20A 5ycnA-1jdiA:
0.0		 5ycnA-1jdiA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 1jdi L-RIBULOSE 5
PHOSPHATE
4-EPIMERASE
(Escherichia
coli) 		3 / 3 TRP A 176
ILE A 149
GLU A 154
 None
 0.83A 6hcxA-1jdiA:
undetectable		 6hcxA-1jdiA:
15.58