SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jdp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 PHE A  22
LEU A  24
SER A  61
 None
None
CL  A 503 (-2.9A)
 0.87A 1e7aA-1jdpA:
0.0		 1e7aA-1jdpA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 ASN A 310
PHE A 290
VAL A 313
 None
 0.82A 1kijA-1jdpA:
0.0		 1kijA-1jdpA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 PHE A 312
LEU A 115
MET A 139
 None
 0.69A 1mx1D-1jdpA:
2.8		 1mx1D-1jdpA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 274
ALA A 270
LEU A 227
ARG A 259
MET A 215
 None
 1.47A 1qktA-1jdpA:
undetectable		 1qktA-1jdpA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		4 / 5 TYR A 271
SER A 256
THR A 276
ASN A 243
 None
 1.29A 1yvpA-1jdpA:
5.2		 1yvpA-1jdpA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		5 / 11 VAL A 298
GLU A  32
ALA A  30
ASP A 318
PHE A 290
 None
 1.16A 2admB-1jdpA:
3.1		 2admB-1jdpA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		5 / 10 LEU A 274
ALA A 270
LEU A 227
ARG A 259
MET A 215
 None
 1.33A 2ocfA-1jdpA:
0.0		 2ocfA-1jdpA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 LEU A 107
PRO A 108
ARG A  74
 None
 0.57A 2qd5A-1jdpA:
4.0		 2qd5A-1jdpA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		4 / 7 TYR A 189
PHE A 191
ILE A 202
ASN A 205
 None
 1.25A 2zseA-1jdpA:
0.7		 2zseA-1jdpA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		5 / 12 GLY A 174
GLY A 140
ALA A 135
ALA A 116
GLU A  92
 None
 1.09A 3g8bA-1jdpA:
3.3		 3g8bA-1jdpA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REQ_A_ADNA801_1
(METHYLMALONYL-COA
MUTASE)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
C-TYPE NATRIURETIC
PEPTIDE
(Homo
sapiens) 		4 / 4 TYR A  93
TYR A 169
GLU A 173
GLY H  19
 None
 1.36A 3reqA-1jdpA:
5.1		 3reqA-1jdpA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		4 / 8 ASP A 362
ILE A 361
GLY A 365
GLN A 346
 None
 0.78A 4acbB-1jdpA:
5.9
4acbC-1jdpA:
6.0		 4acbB-1jdpA:
22.31
4acbC-1jdpA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 ASN A 243
LEU A 146
PHE A 241
 None
 0.80A 4dajB-1jdpA:
undetectable		 4dajB-1jdpA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 ARG A 259
TRP A 257
GLY A 255
 None
 0.65A 4e7cA-1jdpA:
0.0		 4e7cA-1jdpA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		4 / 7 TYR A 136
GLU A  92
TYR A  93
GLU A 165
 None
 1.22A 4mi4A-1jdpA:
0.9
4mi4C-1jdpA:
0.2		 4mi4A-1jdpA:
17.46
4mi4C-1jdpA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 298
THR A  25
ARG A  26
 None
 0.78A 5b2tB-1jdpA:
2.3		 5b2tB-1jdpA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		4 / 5 PHE A 371
PHE A 391
LEU A 280
LEU A 146
 None
 1.30A 5veuH-1jdpA:
0.0		 5veuH-1jdpA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		3 / 3 ASP A 318
PHE A 287
ARG A 281
 None
 0.91A 5yw0A-1jdpA:
0.0		 5yw0A-1jdpA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		5 / 12 GLY A 315
ASP A 318
ILE A 355
VAL A 359
ALA A  30
 None
 0.98A 6bq4B-1jdpA:
undetectable		 6bq4B-1jdpA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR
(Homo
sapiens) 		4 / 8 ASP A 161
GLY A  64
SER A  61
ASN A 167
 None
None
CL  A 503 (-2.9A)
None
 0.67A 6giqL-1jdpA:
0.1
6giqP-1jdpA:
0.0
6giqT-1jdpA:
0.0		 6giqL-1jdpA:
23.34
6giqP-1jdpA:
16.78
6giqT-1jdpA:
8.85