SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jdz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 LEU A  29
LEU A 138
LEU A 231
VAL A  20
ILE A  85
 None
 1.14A 1ee2A-1jdzA:
undetectable		 1ee2A-1jdzA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 LEU A  29
LEU A 138
LEU A 231
VAL A  20
ILE A  85
 None
 1.17A 1ee2B-1jdzA:
2.3		 1ee2B-1jdzA:
21.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 10 ARG A  86
THR A  89
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.62A 1jdvA-1jdzA:
41.9
1jdvD-1jdzA:
41.9		 1jdvA-1jdzA:
100.00
1jdvD-1jdzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 10 ARG A  86
THR A  89
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.63A 1jdvB-1jdzA:
42.2
1jdvC-1jdzA:
42.1		 1jdvB-1jdzA:
100.00
1jdvC-1jdzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 10 ARG A  86
THR A  89
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.62A 1jdvA-1jdzA:
41.9
1jdvD-1jdzA:
41.9		 1jdvA-1jdzA:
100.00
1jdvD-1jdzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		8 / 12 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.59A 1jdvE-1jdzA:
42.3
1jdvF-1jdzA:
42.0		 1jdvE-1jdzA:
100.00
1jdvF-1jdzA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		3 / 3 THR A 185
LEU A 189
VAL A 192
 None
 0.43A 1mz9E-1jdzA:
undetectable		 1mz9E-1jdzA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 5 ASP A 225
LEU A  32
ALA A 229
LEU A 147
 None
 1.16A 1nh8A-1jdzA:
0.0		 1nh8A-1jdzA:
23.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.75A 1odiA-1jdzA:
34.1		 1odiA-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.21A 1odiA-1jdzA:
34.1		 1odiA-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.70A 1odiB-1jdzA:
34.1		 1odiB-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.21A 1odiB-1jdzA:
34.1		 1odiB-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.71A 1odiC-1jdzA:
34.2		 1odiC-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.22A 1odiC-1jdzA:
34.2		 1odiC-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.70A 1odiD-1jdzA:
34.0		 1odiD-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.25A 1odiD-1jdzA:
34.0		 1odiD-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.69A 1odiE-1jdzA:
34.1		 1odiE-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.24A 1odiE-1jdzA:
34.1		 1odiE-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.72A 1odiF-1jdzA:
34.0		 1odiF-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.22A 1odiF-1jdzA:
34.0		 1odiF-1jdzA:
40.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 9 ARG A  86
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.60A 1pk7A-1jdzA:
33.7		 1pk7A-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 8 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.70A 1pk7B-1jdzA:
34.0		 1pk7B-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 10 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.68A 1pk7C-1jdzA:
34.0		 1pk7C-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 10 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.65A 1pk9A-1jdzA:
33.7		 1pk9A-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 9 ARG A  86
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.64A 1pk9B-1jdzA:
33.8		 1pk9B-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.68A 1pk9C-1jdzA:
32.6		 1pk9C-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 10 ARG A  86
GLY A  91
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.59A 1pw7A-1jdzA:
33.8		 1pw7A-1jdzA:
32.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 9 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.72A 1pw7B-1jdzA:
34.0		 1pw7B-1jdzA:
32.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.64A 1pw7C-1jdzA:
34.0		 1pw7C-1jdzA:
32.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 6 ASN A 176
LEU A  93
TRP A 171
PHE A 167
 None
 0.94A 1ru9H-1jdzA:
undetectable
1ru9L-1jdzA:
undetectable		 1ru9H-1jdzA:
22.18
1ru9L-1jdzA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 6 ASN A 176
LEU A  93
TRP A 171
PHE A 167
 None
 0.96A 1rukH-1jdzA:
undetectable
1rukL-1jdzA:
undetectable		 1rukH-1jdzA:
22.18
1rukL-1jdzA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.71A 1vhwA-1jdzA:
33.8
1vhwD-1jdzA:
33.9		 1vhwA-1jdzA:
29.92
1vhwD-1jdzA:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 ARG A  86
GLY A  91
VAL A 179
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.67A 1vhwB-1jdzA:
33.7
1vhwF-1jdzA:
33.7		 1vhwB-1jdzA:
29.92
1vhwF-1jdzA:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.72A 1vhwC-1jdzA:
33.8
1vhwE-1jdzA:
33.9		 1vhwC-1jdzA:
29.92
1vhwE-1jdzA:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.72A 1vhwA-1jdzA:
33.8
1vhwD-1jdzA:
33.9		 1vhwA-1jdzA:
29.92
1vhwD-1jdzA:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.71A 1vhwC-1jdzA:
33.8
1vhwE-1jdzA:
33.9		 1vhwC-1jdzA:
29.92
1vhwE-1jdzA:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 10 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.70A 1vhwB-1jdzA:
33.7
1vhwF-1jdzA:
33.7		 1vhwB-1jdzA:
29.92
1vhwF-1jdzA:
29.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		8 / 10 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.73A 1z35A-1jdzA:
33.6		 1z35A-1jdzA:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.30A 1z35A-1jdzA:
33.6		 1z35A-1jdzA:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		8 / 9 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.66A 1z37A-1jdzA:
33.6		 1z37A-1jdzA:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.32A 1z37A-1jdzA:
33.6		 1z37A-1jdzA:
34.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.68A 2ac7A-1jdzA:
33.8
2ac7B-1jdzA:
33.9		 2ac7A-1jdzA:
36.25
2ac7B-1jdzA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.67A 2ac7A-1jdzA:
33.8
2ac7B-1jdzA:
33.9		 2ac7A-1jdzA:
36.25
2ac7B-1jdzA:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  28
LEU A  29
LEU A  18
LEU A 138
VAL A 202
 None
 1.09A 2pnjA-1jdzA:
4.1		 2pnjA-1jdzA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 7 ALA A  60
THR A  61
ALA A  26
ARG A  27
 None
 0.84A 2ql8A-1jdzA:
1.1
2ql8B-1jdzA:
1.1		 2ql8A-1jdzA:
21.78
2ql8B-1jdzA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 SER A 156
LEU A 201
VAL A 203
ILE A 103
ALA A 208
 None
 1.11A 2zbzA-1jdzA:
0.0		 2zbzA-1jdzA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 VAL A 179
SER A 156
LEU A 201
VAL A 203
ALA A 208
 FMB  A 270 (-4.6A)
None
None
None
None
 1.22A 2zbzA-1jdzA:
0.0		 2zbzA-1jdzA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 THR A  89
GLY A  91
PHE A 160
GLU A 180
MET A 181
 SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
None
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
 0.62A 3kvrA-1jdzA:
24.5		 3kvrA-1jdzA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 THR A  89
GLY A  91
PHE A 160
GLU A 180
MET A 181
 SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
None
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
 0.62A 3kvrB-1jdzA:
24.4		 3kvrB-1jdzA:
24.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 ARG A  86
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.61A 3u40A-1jdzA:
33.2
3u40F-1jdzA:
33.4		 3u40A-1jdzA:
34.57
3u40F-1jdzA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 ARG A  86
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.57A 3u40B-1jdzA:
32.9
3u40C-1jdzA:
21.6		 3u40B-1jdzA:
34.57
3u40C-1jdzA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 12 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.59A 3u40B-1jdzA:
32.9
3u40C-1jdzA:
21.6		 3u40B-1jdzA:
34.57
3u40C-1jdzA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.58A 3u40D-1jdzA:
33.2
3u40E-1jdzA:
32.6		 3u40D-1jdzA:
34.57
3u40E-1jdzA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		6 / 12 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.57A 3u40D-1jdzA:
33.2
3u40E-1jdzA:
32.6		 3u40D-1jdzA:
34.57
3u40E-1jdzA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 ARG A  86
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.61A 3u40A-1jdzA:
33.2
3u40F-1jdzA:
33.4		 3u40A-1jdzA:
34.57
3u40F-1jdzA:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		8 / 11 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.68A 3uawA-1jdzA:
21.2		 3uawA-1jdzA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 11 MET A 181
ARG A  86
THR A  89
GLU A 182
SER A 204
 FMB  A 270 (-3.8A)
SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 1.23A 3uawA-1jdzA:
21.2		 3uawA-1jdzA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 10 ARG A  86
THR A  89
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
SO4  A 250 ( 3.0A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.67A 3uayA-1jdzA:
21.6		 3uayA-1jdzA:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 5 GLU A  55
GLY A  54
TYR A  52
GLN A  34
 None
 1.21A 3w9tB-1jdzA:
0.0		 3w9tB-1jdzA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 5 GLU A  55
GLY A  54
TYR A  52
GLN A  34
 None
 1.27A 3w9tD-1jdzA:
0.0		 3w9tD-1jdzA:
19.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		8 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
None
 0.78A 4d9hA-1jdzA:
33.3		 4d9hA-1jdzA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 GLY A  91
VAL A 179
MET A 181
GLU A 182
ASP A 205
 FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
None
 0.60A 4da6A-1jdzA:
32.7		 4da6A-1jdzA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 GLY A  91
VAL A 179
MET A 181
GLU A 182
SER A 204
 FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.67A 4da6A-1jdzA:
32.7		 4da6A-1jdzA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 10 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.68A 4da7A-1jdzA:
32.9		 4da7A-1jdzA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		8 / 11 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
None
 0.85A 4danA-1jdzA:
20.0		 4danA-1jdzA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 12 ARG A  86
GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
 0.75A 4danA-1jdzA:
20.0
4danB-1jdzA:
32.8		 4danA-1jdzA:
31.01
4danB-1jdzA:
31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 12 GLY A  91
VAL A 179
GLU A 180
MET A 181
ASP A 205
 FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
None
 0.75A 4danA-1jdzA:
20.0
4danB-1jdzA:
32.8		 4danA-1jdzA:
31.01
4danB-1jdzA:
31.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  76
VAL A  17
ALA A  14
ALA A   8
THR A  39
 None
 1.13A 4fiaA-1jdzA:
undetectable		 4fiaA-1jdzA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  76
VAL A  17
ALA A  14
ALA A   8
THR A  39
 None
 1.13A 4fiaA-1jdzA:
undetectable		 4fiaA-1jdzA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 8 LEU A  28
LEU A  29
LEU A  18
VAL A 202
 None
 0.87A 4klaA-1jdzA:
3.3		 4klaA-1jdzA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 4 GLU A 180
GLY A  65
HIS A  62
ARG A  86
 FMB  A 270 (-4.6A)
None
None
SO4  A 250 ( 3.1A)
 1.41A 4r82A-1jdzA:
0.0
4r82B-1jdzA:
0.0		 4r82A-1jdzA:
24.19
4r82B-1jdzA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 4 PHE A 142
ASP A 232
GLY A 226
SER A 141
 None
 1.20A 4xp9C-1jdzA:
0.0		 4xp9C-1jdzA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 5 GLY A  65
TYR A 110
GLU A 182
ASP A 158
 None
None
FMB  A 270 (-2.8A)
None
 1.29A 4xueA-1jdzA:
undetectable		 4xueA-1jdzA:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		4 / 8 ILE A 103
VAL A 105
SER A 156
CYH A 183
 None
 1.17A 5dqyA-1jdzA:
undetectable		 5dqyA-1jdzA:
18.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 ARG A  86
GLY A  91
VAL A 179
MET A 181
GLU A 182
 SO4  A 250 ( 3.1A)
FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.65A 5i3cA-1jdzA:
33.7		 5i3cA-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 GLY A  91
GLU A 180
MET A 181
GLU A 182
ASP A 205
 FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
None
 0.84A 5i3cB-1jdzA:
33.6		 5i3cB-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 10 GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
 FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
 0.65A 5i3cB-1jdzA:
33.6		 5i3cB-1jdzA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		7 / 11 GLY A  91
VAL A 179
GLU A 180
MET A 181
GLU A 182
SER A 204
ASP A 205
 FMB  A 270 (-3.3A)
FMB  A 270 (-4.6A)
FMB  A 270 (-4.6A)
FMB  A 270 (-3.8A)
FMB  A 270 (-2.8A)
FMB  A 270 (-3.2A)
None
 0.66A 5i3cC-1jdzA:
33.7		 5i3cC-1jdzA:
32.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 ASP A 232
ALA A 198
ILE A  85
GLY A 226
SER A 141
 None
 1.31A 6awoA-1jdzA:
0.0		 6awoA-1jdzA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		5 / 9 ASP A 232
ALA A 198
ILE A  85
GLY A 226
SER A 141
 None
 1.31A 6awqA-1jdzA:
0.0		 6awqA-1jdzA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1jdz 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(Sulfolobus
solfataricus) 		3 / 3 TYR A  48
PRO A  36
LEU A  33
 None
 0.91A 6beoA-1jdzA:
undetectable		 6beoA-1jdzA:
5.36