SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1je6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 156
ASP A  72
LEU A  73
THR A 143
PHE A 110
 None
 1.28A 1xoqA-1je6A:
undetectable		 1xoqA-1je6A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 156
ASP A  72
LEU A  73
THR A 143
PHE A 110
 None
 1.30A 1xoqB-1je6A:
undetectable		 1xoqB-1je6A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 ALA A 135
LEU A 138
ALA A 139
THR A 143
GLN A  91
 None
 1.09A 2jjpA-1je6A:
0.0		 2jjpA-1je6A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		4 / 8 PHE A 117
TYR A 157
LEU A  73
LEU A  90
 None
 0.87A 2w98B-1je6A:
undetectable		 2w98B-1je6A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		5 / 10 GLU A  92
LEU A 122
GLN A 161
GLU A  97
ARG A  94
 None
 1.43A 3kp3A-1je6A:
0.5
3kp3B-1je6A:
undetectable		 3kp3A-1je6A:
20.45
3kp3B-1je6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		4 / 5 ASP A  72
THR A  76
LEU A  73
GLU A  92
 None
 1.32A 4a3pA-1je6A:
0.0		 4a3pA-1je6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 1je6 MHC CLASS I
CHAIN-RELATED
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  80
THR A  76
TRP A 146
LEU A  90
LEU A  73
 None
 1.43A 4pbhA-1je6A:
undetectable		 4pbhA-1je6A:
18.88