SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jed'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 ALA A  75
VAL A  68
TRP A  80
 None
 0.80A 1c4dC-1jedA:
undetectable
1c4dD-1jedA:
undetectable		 1c4dC-1jedA:
4.23
1c4dD-1jedA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 TRP A  80
ALA A  75
VAL A  68
 None
 0.87A 1c4dC-1jedA:
undetectable
1c4dD-1jedA:
undetectable		 1c4dC-1jedA:
4.23
1c4dD-1jedA:
4.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 406
LEU A 404
VAL A 496
ALA A 414
ILE A 398
 None
 1.04A 1epbA-1jedA:
undetectable		 1epbA-1jedA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 104
PRO A 123
VAL A 154
GLY A 155
 None
 1.02A 1hrkA-1jedA:
2.5		 1hrkA-1jedA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 104
PRO A 123
VAL A 154
GLY A 155
 None
 1.04A 1hrkB-1jedA:
2.4		 1hrkB-1jedA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 490
LEU A 411
ALA A 414
LEU A 415
 ACY  A 553 (-3.5A)
None
None
None
 0.87A 1hwiD-1jedA:
undetectable		 1hwiD-1jedA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.06A 1kifA-1jedA:
2.3		 1kifA-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.05A 1kifB-1jedA:
2.2		 1kifB-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.05A 1kifC-1jedA:
2.1		 1kifC-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.05A 1kifD-1jedA:
2.1		 1kifD-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.05A 1kifE-1jedA:
2.3		 1kifE-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.06A 1kifF-1jedA:
2.1		 1kifF-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.06A 1kifG-1jedA:
2.1		 1kifG-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.05A 1kifH-1jedA:
2.2		 1kifH-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OAF_A_ASCA1253_0
(ASCORBATE PEROXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 PRO A 260
LEU A 261
HIS A 222
ARG A 278
 None
 1.32A 1oafA-1jedA:
0.0		 1oafA-1jedA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  44
THR A  85
GLU A 128
 None
 0.67A 1pj7A-1jedA:
undetectable		 1pj7A-1jedA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 207
ALA A 212
ALA A 215
ALA A 211
VAL A 331
 ADP  A 635 (-4.9A)
None
None
None
ADP  A 635 (-3.7A)
 1.39A 1rbpA-1jedA:
0.0		 1rbpA-1jedA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 TYR A 317
LEU A 313
GLY A 267
ASP A 309
 None
None
None
NA  A 522 (-2.4A)
 1.02A 1rmtC-1jedA:
2.2		 1rmtC-1jedA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 ALA A  75
VAL A  68
TRP A  80
 None
 0.93A 1tkqB-1jedA:
undetectable		 1tkqB-1jedA:
4.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.84A 1v54A-1jedA:
0.0
1v54J-1jedA:
undetectable		 1v54A-1jedA:
21.17
1v54J-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.93A 1v54N-1jedA:
0.1
1v54W-1jedA:
0.0		 1v54N-1jedA:
21.17
1v54W-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.96A 1v55A-1jedA:
0.0
1v55J-1jedA:
undetectable		 1v55A-1jedA:
21.17
1v55J-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.95A 1v55N-1jedA:
0.0
1v55W-1jedA:
undetectable		 1v55N-1jedA:
21.17
1v55W-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.15A 1ve9A-1jedA:
2.3		 1ve9A-1jedA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.07A 2du8G-1jedA:
2.1		 2du8G-1jedA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 473
ILE A 398
ARG A 391
GLY A 507
 None
 1.07A 2du8J-1jedA:
2.1		 2du8J-1jedA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.85A 2dyrA-1jedA:
0.1
2dyrJ-1jedA:
undetectable		 2dyrA-1jedA:
21.17
2dyrJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.89A 2dysA-1jedA:
0.0
2dysJ-1jedA:
undetectable		 2dysA-1jedA:
21.17
2dysJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.85A 2dysN-1jedA:
0.0
2dysW-1jedA:
0.0		 2dysN-1jedA:
21.17
2dysW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.85A 2eijA-1jedA:
0.0
2eijJ-1jedA:
undetectable		 2eijA-1jedA:
21.17
2eijJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.87A 2eijN-1jedA:
0.0
2eijW-1jedA:
0.0		 2eijN-1jedA:
21.17
2eijW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.80A 2eikA-1jedA:
0.0
2eikJ-1jedA:
0.0		 2eikA-1jedA:
21.17
2eikJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.88A 2eikN-1jedA:
0.0
2eikW-1jedA:
0.0		 2eikN-1jedA:
21.17
2eikW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.82A 2eilA-1jedA:
0.0
2eilJ-1jedA:
0.0		 2eilA-1jedA:
21.17
2eilJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.84A 2eilN-1jedA:
0.0
2eilW-1jedA:
0.0		 2eilN-1jedA:
21.17
2eilW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.94A 2einA-1jedA:
0.0
2einJ-1jedA:
undetectable		 2einA-1jedA:
21.17
2einJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 MET A 330
VAL A 325
GLU A 312
 ADP  A 635 (-3.3A)
None
None
 0.92A 2x9gA-1jedA:
3.0		 2x9gA-1jedA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.90A 2zxwA-1jedA:
undetectable
2zxwJ-1jedA:
0.0		 2zxwA-1jedA:
21.17
2zxwJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 SER A  54
LEU A  56
THR A  57
ASP A  64
ILE A 276
 None
 1.12A 3a35A-1jedA:
2.0		 3a35A-1jedA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 SER A  54
LEU A  56
THR A  57
ASP A  64
ILE A 276
 None
 1.08A 3a35B-1jedA:
3.1		 3a35B-1jedA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 SER A  54
LEU A  56
THR A  57
ASP A  64
ILE A 276
 None
 1.17A 3a3bA-1jedA:
1.9		 3a3bA-1jedA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.97A 3abkA-1jedA:
0.0
3abkJ-1jedA:
0.0		 3abkA-1jedA:
21.17
3abkJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.73A 3ablN-1jedA:
0.0
3ablW-1jedA:
0.0		 3ablN-1jedA:
21.17
3ablW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.79A 3abmA-1jedA:
0.0
3abmJ-1jedA:
0.0		 3abmA-1jedA:
21.17
3abmJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.99A 3abmN-1jedA:
0.0
3abmW-1jedA:
0.0		 3abmN-1jedA:
21.17
3abmW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
ARG A  40
THR A  38
LEU A  37
 None
 0.83A 3ag1N-1jedA:
0.0
3ag1W-1jedA:
0.0		 3ag1N-1jedA:
21.17
3ag1W-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.93A 3ag3A-1jedA:
0.0
3ag3J-1jedA:
undetectable		 3ag3A-1jedA:
21.17
3ag3J-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
 None
 0.92A 3ag4N-1jedA:
0.0
3ag4W-1jedA:
0.0		 3ag4N-1jedA:
21.17
3ag4W-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.85A 3asnA-1jedA:
0.0
3asnJ-1jedA:
undetectable		 3asnA-1jedA:
21.17
3asnJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  48
LEU A  49
THR A  38
LEU A  37
 None
 0.80A 3asnN-1jedA:
0.0
3asnW-1jedA:
undetectable		 3asnN-1jedA:
21.17
3asnW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.90A 3asnN-1jedA:
0.0
3asnW-1jedA:
undetectable		 3asnN-1jedA:
21.17
3asnW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.84A 3asoA-1jedA:
0.0
3asoJ-1jedA:
undetectable		 3asoA-1jedA:
21.17
3asoJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.94A 3asoN-1jedA:
0.0
3asoW-1jedA:
0.0		 3asoN-1jedA:
21.17
3asoW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  37
THR A  38
GLY A 150
ILE A  84
 None
 0.83A 3jusA-1jedA:
0.0		 3jusA-1jedA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU A  37
THR A  38
GLY A 150
ILE A  84
 None
 0.83A 3jusA-1jedA:
0.0		 3jusA-1jedA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A 357
GLY A 358
THR A 359
 None
 0.11A 3k9wA-1jedA:
9.8		 3k9wA-1jedA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 4 GLY A 306
TYR A 305
GLY A 267
ASP A 268
 NA  A 522 ( 4.3A)
None
None
None
 1.24A 3kl3A-1jedA:
undetectable		 3kl3A-1jedA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 128
LEU A 145
LEU A 227
 None
None
TRS  A1415 ( 4.6A)
 0.78A 3ohtA-1jedA:
undetectable		 3ohtA-1jedA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 128
LEU A 145
LEU A 227
 None
None
TRS  A1415 ( 4.6A)
 0.74A 3ohtB-1jedA:
undetectable		 3ohtB-1jedA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 365
LEU A 361
GLU A 370
ILE A 371
 None
 0.97A 3s56B-1jedA:
undetectable		 3s56B-1jedA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
LEU A  49
ARG A  40
THR A  38
 None
 1.18A 3wg7A-1jedA:
0.0
3wg7J-1jedA:
0.0		 3wg7A-1jedA:
21.17
3wg7J-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 291
GLY A 294
VAL A 272
SER A  72
 None
 0.91A 4acbB-1jedA:
undetectable
4acbC-1jedA:
undetectable		 4acbB-1jedA:
22.34
4acbC-1jedA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 158
LEU A 104
ALA A 113
LEU A  49
LEU A  42
 None
 1.09A 4p65C-1jedA:
undetectable
4p65D-1jedA:
undetectable
4p65J-1jedA:
undetectable
4p65L-1jedA:
undetectable		 4p65C-1jedA:
3.00
4p65D-1jedA:
7.01
4p65J-1jedA:
7.01
4p65L-1jedA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 255
LEU A 258
PRO A 223
ARG A 186
 None
None
None
ACY  A 555 (-3.5A)
 1.23A 4yv5B-1jedA:
undetectable		 4yv5B-1jedA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 255
LEU A 258
PRO A 223
ARG A 186
 None
None
None
ACY  A 555 (-3.5A)
 1.24A 4yv5A-1jedA:
undetectable		 4yv5A-1jedA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 1.13A 5b1aA-1jedA:
0.0
5b1aJ-1jedA:
0.0		 5b1aA-1jedA:
21.17
5b1aJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  48
LEU A  49
THR A  38
LEU A  37
 None
 0.77A 5b1bA-1jedA:
0.0
5b1bJ-1jedA:
undetectable		 5b1bA-1jedA:
21.17
5b1bJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 1.17A 5b3sA-1jedA:
0.0
5b3sJ-1jedA:
undetectable		 5b3sA-1jedA:
21.17
5b3sJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  82
THR A  38
ALA A 293
SER A 143
ILE A 142
 None
None
ADP  A 635 (-4.4A)
None
None
 1.06A 5iwuA-1jedA:
0.0		 5iwuA-1jedA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.91A 5iy5A-1jedA:
0.0
5iy5J-1jedA:
0.0		 5iy5A-1jedA:
21.17
5iy5J-1jedA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  48
ARG A  40
THR A  38
LEU A  37
 None
 0.94A 5iy5N-1jedA:
0.0
5iy5W-1jedA:
0.0		 5iy5N-1jedA:
21.17
5iy5W-1jedA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 ILE A  48
ASP A  11
LEU A  74
GLY A 282
TYR A 281
 None
 1.12A 5uxdB-1jedA:
0.0		 5uxdB-1jedA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 233
ILE A 246
HIS A 204
PHE A 255
 None
None
ADP  A 635 (-4.5A)
None
 0.79A 5vkqB-1jedA:
undetectable
5vkqC-1jedA:
undetectable		 5vkqB-1jedA:
14.70
5vkqC-1jedA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 233
ILE A 246
HIS A 204
PHE A 255
 None
None
ADP  A 635 (-4.5A)
None
 0.80A 5vkqC-1jedA:
0.0
5vkqD-1jedA:
0.0		 5vkqC-1jedA:
14.70
5vkqD-1jedA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.71A 5x1fA-1jedA:
0.1
5x1fJ-1jedA:
0.0		 5x1fA-1jedA:
21.17
5x1fJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  48
LEU A  49
THR A  38
LEU A  37
 None
 0.75A 5xdqA-1jedA:
0.1
5xdqJ-1jedA:
0.0		 5xdqA-1jedA:
21.17
5xdqJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.91A 5xdqN-1jedA:
0.0
5xdqW-1jedA:
undetectable		 5xdqN-1jedA:
21.17
5xdqW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.80A 5xdxA-1jedA:
0.0
5xdxJ-1jedA:
0.0		 5xdxA-1jedA:
21.17
5xdxJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 306
PRO A 295
GLY A 296
ASP A 309
ASP A 303
 NA  A 522 ( 4.3A)
None
None
NA  A 522 (-2.4A)
CA  A 519 (-2.5A)
 1.31A 5yniA-1jedA:
undetectable		 5yniA-1jedA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 306
PRO A 295
GLY A 296
ASP A 309
ASP A 303
 NA  A 522 ( 4.3A)
None
None
NA  A 522 (-2.4A)
CA  A 519 (-2.5A)
 1.30A 5ynmA-1jedA:
undetectable		 5ynmA-1jedA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
ARG A  40
THR A  38
LEU A  37
 None
 0.99A 5z86N-1jedA:
0.0
5z86W-1jedA:
0.0		 5z86N-1jedA:
21.17
5z86W-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  48
LEU A  49
THR A  38
LEU A  37
 None
 0.82A 5zcoA-1jedA:
0.0
5zcoJ-1jedA:
0.0		 5zcoA-1jedA:
21.17
5zcoJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
ARG A  40
THR A  38
LEU A  37
 None
 0.97A 5zcoN-1jedA:
0.0
5zcoW-1jedA:
0.0		 5zcoN-1jedA:
21.17
5zcoW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 1.11A 5zcpA-1jedA:
0.0
5zcpJ-1jedA:
undetectable		 5zcpA-1jedA:
21.17
5zcpJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 8 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.92A 5zcpN-1jedA:
0.0
5zcpW-1jedA:
0.0		 5zcpN-1jedA:
21.17
5zcpW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  48
LEU A  49
THR A  38
LEU A  37
 None
 0.77A 5zcqA-1jedA:
0.0
5zcqJ-1jedA:
undetectable		 5zcqA-1jedA:
21.17
5zcqJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  48
LEU A  49
THR A  38
LEU A  37
 None
 0.78A 5zcqN-1jedA:
0.0
5zcqW-1jedA:
0.0		 5zcqN-1jedA:
21.17
5zcqW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 8 VAL A 209
TYR A 249
HIS A 204
TYR A 377
 None
None
ADP  A 635 (-4.5A)
None
 1.05A 6gneB-1jedA:
undetectable		 6gneB-1jedA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 500
VAL A 499
PHE A 422
PHE A 396
TYR A 428
 None
 1.46A 6mxtA-1jedA:
0.0		 6mxtA-1jedA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
LEU A  49
ARG A  40
THR A  38
 None
 1.01A 6nmfN-1jedA:
0.0
6nmfW-1jedA:
0.0		 6nmfN-1jedA:
21.17
6nmfW-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 7 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.83A 6nmpA-1jedA:
0.0
6nmpJ-1jedA:
0.0		 6nmpA-1jedA:
21.17
6nmpJ-1jedA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jed SULFATE
ADENYLYLTRANSFERASE
(Saccharomyces
cerevisiae) 		5 / 5 ILE A  48
LEU A  49
ARG A  40
THR A  38
LEU A  37
 None
 0.94A 6nmpN-1jedA:
0.0
6nmpW-1jedA:
0.0		 6nmpN-1jedA:
21.17
6nmpW-1jedA:
8.97