SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1jf0 OBELIN
(Obelia
longissima) 		4 / 7 PHE A  72
TYR A  28
ILE A  50
TRP A 114
 CZH  A 197 ( 4.6A)
None
None
CZH  A 197 (-3.7A)
 0.82A 1tdnA-1jf0A:
undetectable		 1tdnA-1jf0A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1jf0 OBELIN
(Obelia
longissima) 		4 / 8 HIS A 175
ILE A 144
TRP A 179
TYR A 138
 CZH  A 197 (-3.5A)
CZH  A 197 ( 4.5A)
CZH  A 197 (-3.7A)
CZH  A 197 (-4.3A)
 1.28A 3ccfB-1jf0A:
undetectable		 3ccfB-1jf0A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 1jf0 OBELIN
(Obelia
longissima) 		3 / 3 TRP A  18
GLN A 174
THR A 181
 None
 0.89A 4m2xA-1jf0A:
undetectable		 4m2xA-1jf0A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1jf0 OBELIN
(Obelia
longissima) 		5 / 12 GLU A 170
ALA A 186
THR A  11
ARG A 173
LEU A 176
 None
 1.27A 5m54B-1jf0A:
undetectable		 5m54B-1jf0A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1jf0 OBELIN
(Obelia
longissima) 		4 / 6 VAL A   7
LEU A 100
LEU A 110
GLU A 107
 None
 0.98A 5tudD-1jf0A:
undetectable		 5tudD-1jf0A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1jf0 OBELIN
(Obelia
longissima) 		3 / 3 LYS A 136
SER A 145
SER A 147
 None
 0.95A 6gbfA-1jf0A:
undetectable		 6gbfA-1jf0A:
14.83