SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.94A 1v55A-1jfiB:
undetectable
1v55J-1jfiB:
1.5		 1v55A-1jfiB:
14.49
1v55J-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 8 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.91A 1v55N-1jfiB:
undetectable
1v55W-1jfiB:
1.6		 1v55N-1jfiB:
14.49
1v55W-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE A  20
ALA A  41
ILE A  38
THR B 144
VAL B 140
 None
 1.22A 1vq1A-1jfiA:
undetectable		 1vq1A-1jfiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1jfi TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens) 		4 / 5 LEU B 175
PRO B 168
VAL B 171
ILE B 172
 None
 1.01A 2aoiB-1jfiB:
undetectable		 2aoiB-1jfiB:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 1.00A 3ablA-1jfiB:
undetectable
3ablJ-1jfiB:
1.4		 3ablA-1jfiB:
14.49
3ablJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 8 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.96A 3asnN-1jfiB:
undetectable
3asnW-1jfiB:
1.6		 3asnN-1jfiB:
14.49
3asnW-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 1jfi TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens) 		4 / 7 LEU B 149
ALA B 174
VAL B 187
ILE B 150
 None
 0.92A 3wsjB-1jfiB:
undetectable		 3wsjB-1jfiB:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 1jfi TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens) 		3 / 3 ARG B 115
GLU B 137
ASN B 133
 None
 0.86A 4imaD-1jfiB:
undetectable		 4imaD-1jfiB:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 1jfi TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens) 		3 / 3 ARG B 115
GLU B 137
ASN B 133
 None
 0.92A 4ip7D-1jfiB:
undetectable		 4ip7D-1jfiB:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.94A 5b1aA-1jfiB:
undetectable
5b1aJ-1jfiB:
1.6		 5b1aA-1jfiB:
14.49
5b1aJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.94A 5b1bA-1jfiB:
undetectable
5b1bJ-1jfiB:
1.6		 5b1bA-1jfiB:
14.49
5b1bJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.96A 5b3sA-1jfiB:
undetectable
5b3sJ-1jfiB:
1.5		 5b3sA-1jfiB:
14.49
5b3sJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.99A 5iy5A-1jfiB:
undetectable
5iy5J-1jfiB:
1.7		 5iy5A-1jfiB:
14.49
5iy5J-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.92A 5xdqA-1jfiB:
undetectable
5xdqJ-1jfiB:
1.7		 5xdqA-1jfiB:
14.49
5xdqJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.94A 5xdqN-1jfiB:
undetectable
5xdqW-1jfiB:
1.7		 5xdqN-1jfiB:
14.49
5xdqW-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.97A 5xdxA-1jfiB:
undetectable
5xdxJ-1jfiB:
1.5		 5xdxA-1jfiB:
14.49
5xdxJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.98A 5zcpA-1jfiB:
undetectable
5zcpJ-1jfiB:
1.6		 5zcpA-1jfiB:
14.49
5zcpJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.97A 5zcqA-1jfiB:
undetectable
5zcqJ-1jfiB:
1.6		 5zcqA-1jfiB:
14.49
5zcqJ-1jfiB:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1jfi TRANSCRIPTION
REGULATOR NC2 ALPHA
CHAIN
TRANSCRIPTION
REGULATOR NC2 BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ILE B 122
LEU B 126
THR A  67
LEU A  70
 None
 0.93A 6nmpA-1jfiB:
undetectable
6nmpJ-1jfiB:
1.7		 6nmpA-1jfiB:
14.49
6nmpJ-1jfiB:
12.85