SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jgc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 10 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.14A 1pxxA-1jgcA:
undetectable		 1pxxA-1jgcA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.08A 2aylB-1jgcA:
undetectable		 2aylB-1jgcA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		3 / 3 SER A  48
THR A  86
GLN A  32
 None
 0.76A 2fk8A-1jgcA:
undetectable		 2fk8A-1jgcA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		4 / 8 SER A 116
ILE A   8
LEU A  11
GLY A  67
 None
 0.74A 3dcjB-1jgcA:
undetectable		 3dcjB-1jgcA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.01A 3n8wA-1jgcA:
undetectable		 3n8wA-1jgcA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.07A 3n8zB-1jgcA:
undetectable		 3n8zB-1jgcA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		4 / 5 ALA A  21
GLU A 127
GLU A  94
ALA A  97
 None
 1.49A 3r9tC-1jgcA:
undetectable		 3r9tC-1jgcA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		4 / 5 ALA A  97
GLU A  51
GLU A  18
ALA A  21
 None
 1.42A 3r9tC-1jgcA:
undetectable		 3r9tC-1jgcA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		3 / 3 ASP A  90
TRP A  35
SER A  44
 None
 1.05A 4lrhF-1jgcA:
undetectable		 4lrhF-1jgcA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.20A 4rrwB-1jgcA:
undetectable		 4rrwB-1jgcA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.20A 4rrzB-1jgcA:
undetectable		 4rrzB-1jgcA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		4 / 8 ALA A  60
PRO A  69
LEU A  11
LEU A  15
 None
 1.20A 5dzkF-1jgcA:
undetectable
5dzkT-1jgcA:
undetectable		 5dzkF-1jgcA:
22.07
5dzkT-1jgcA:
1.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 ILE A  79
ASP A  90
HIS A  28
GLU A  94
ILE A  22
 None
None
None
None
HEM  A 201 ( 4.6A)
 1.27A 5igvA-1jgcA:
undetectable		 5igvA-1jgcA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.11A 5ikqA-1jgcA:
undetectable		 5ikqA-1jgcA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.10A 5ikqB-1jgcA:
undetectable		 5ikqB-1jgcA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		5 / 12 VAL A 131
LEU A 134
TYR A  25
GLY A  93
LEU A  98
 None
 1.14A 5ikrA-1jgcA:
undetectable		 5ikrA-1jgcA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		3 / 3 PHE A 133
ASP A  90
LEU A 123
 None
 0.71A 5uhbC-1jgcA:
0.0		 5uhbC-1jgcA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1jgc BACTERIOFERRITIN
(Rhodobacter
capsulatus) 		3 / 3 PHE A 133
ASP A  90
LEU A 123
 None
 0.75A 5uhcC-1jgcA:
0.0		 5uhcC-1jgcA:
10.09