SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1jgu ANTIBODY HEAVY CHAIN
(Mus
musculus) 		5 / 12 LEU H  45
THR H 110
THR H 108
LEU H 170
TYR H 175
 None
 1.27A 1cbrA-1jguH:
undetectable		 1cbrA-1jguH:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1jgu ANTIBODY HEAVY CHAIN
(Mus
musculus) 		5 / 12 LEU H  45
THR H 110
THR H 108
LEU H 170
TYR H 175
 None
 1.27A 1cbrB-1jguH:
undetectable		 1cbrB-1jguH:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1jgu ANTIBODY HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR H 110
GLU H 148
HIS H 199
 None
 0.75A 3g1uB-1jguH:
undetectable		 3g1uB-1jguH:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 1jgu ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H 104
TYR H  90
ALA H 105
TYR H  91
 None
 0.93A 4ae1A-1jguH:
3.8		 4ae1A-1jguH:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1jgu ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 5 THR H  82
GLY H  16
VAL H  12
PRO H  14
 None
 0.95A 4grkA-1jguH:
undetectable		 4grkA-1jguH:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1jgu ANTIBODY HEAVY CHAIN
(Mus
musculus) 		4 / 7 ALA H  88
THR H  87
VAL H 109
GLU H  85
 None
 0.83A 5ecoD-1jguH:
undetectable		 5ecoD-1jguH:
18.07