SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 1jh7 CYCLIC
PHOSPHODIESTERASE
(Arabidopsis
thaliana) 		5 / 9 GLU A 137
ASN A 134
LEU A  30
LEU A  26
LEU A 146
 None
 1.49A 1hwiA-1jh7A:
undetectable		 1hwiA-1jh7A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1jh7 CYCLIC
PHOSPHODIESTERASE
(Arabidopsis
thaliana) 		4 / 6 HIS A  42
ASP A 162
THR A 161
HIS A 119
 UVC  A 201 (-3.5A)
None
UVC  A 201 (-3.4A)
UVC  A 201 (-4.0A)
 1.36A 3ag1A-1jh7A:
undetectable
3ag1C-1jh7A:
undetectable		 3ag1A-1jh7A:
15.94
3ag1C-1jh7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1jh7 CYCLIC
PHOSPHODIESTERASE
(Arabidopsis
thaliana) 		4 / 7 HIS A  42
ASP A 162
THR A 161
HIS A 119
 UVC  A 201 (-3.5A)
None
UVC  A 201 (-3.4A)
UVC  A 201 (-4.0A)
 1.41A 3ag4N-1jh7A:
undetectable
3ag4P-1jh7A:
undetectable		 3ag4N-1jh7A:
15.94
3ag4P-1jh7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1jh7 CYCLIC
PHOSPHODIESTERASE
(Arabidopsis
thaliana) 		4 / 7 HIS A  42
THR A 161
HIS A 119
LEU A  51
 UVC  A 201 (-3.5A)
UVC  A 201 (-3.4A)
UVC  A 201 (-4.0A)
None
 1.19A 5x1fA-1jh7A:
undetectable
5x1fC-1jh7A:
undetectable
5x1fP-1jh7A:
undetectable		 5x1fA-1jh7A:
15.94
5x1fC-1jh7A:
19.70
5x1fP-1jh7A:
19.70