SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jhd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 HIS A 205
TYR A 390
TYR A 391
VAL A 242
PRO A 239
 BR  A2001 ( 4.3A)
None
None
None
BR  A2006 ( 4.7A)
 1.41A 1ituB-1jhdA:
undetectable		 1ituB-1jhdA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 8 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.06A 1os6A-1jhdA:
undetectable		 1os6A-1jhdA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 LEU A 229
GLN A 199
VAL A 226
ARG A 284
ILE A 238
 None
BR  A2008 (-4.0A)
None
None
None
 1.44A 1z95A-1jhdA:
0.0		 1z95A-1jhdA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 10 ALA A  44
ALA A  40
VAL A 163
GLY A 266
ASP A 103
 None
 0.98A 2f16K-1jhdA:
undetectable
2f16L-1jhdA:
undetectable		 2f16K-1jhdA:
20.41
2f16L-1jhdA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 10 ALA A  44
ALA A  40
VAL A 163
GLY A 266
ASP A 103
 None
 0.97A 2f16Y-1jhdA:
undetectable
2f16Z-1jhdA:
undetectable		 2f16Y-1jhdA:
20.41
2f16Z-1jhdA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 5 LEU A 229
VAL A 364
LEU A 368
ARG A 380
 None
 0.90A 2oiqA-1jhdA:
undetectable		 2oiqA-1jhdA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 LEU A 230
LEU A 229
GLN A 199
VAL A 226
ARG A 284
 None
None
BR  A2008 (-4.0A)
None
None
 1.46A 2q7iA-1jhdA:
undetectable		 2q7iA-1jhdA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 LEU A 230
LEU A 229
GLN A 199
VAL A 226
ARG A 284
 None
None
BR  A2008 (-4.0A)
None
None
 1.46A 2q7lA-1jhdA:
undetectable		 2q7lA-1jhdA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 LEU A 230
LEU A 229
GLN A 199
VAL A 226
ARG A 284
 None
None
BR  A2008 (-4.0A)
None
None
 1.43A 2yloA-1jhdA:
undetectable		 2yloA-1jhdA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		3 / 3 PRO A  82
LEU A  84
ARG A 154
 None
 0.91A 3aqiA-1jhdA:
undetectable		 3aqiA-1jhdA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 6 THR A 148
PHE A 149
GLN A  39
LEU A 270
 BR  A2007 ( 4.6A)
None
None
None
 1.18A 3bgdA-1jhdA:
0.0		 3bgdA-1jhdA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		3 / 3 SER A 360
GLY A 361
THR A 362
 None
SO4  A1002 (-3.6A)
None
 0.17A 3k9wA-1jhdA:
9.1		 3k9wA-1jhdA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 6 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.01A 3sj1X-1jhdA:
0.0		 3sj1X-1jhdA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 5 THR A 179
GLY A  50
PRO A  12
TYR A  16
 None
 1.09A 3u8qA-1jhdA:
undetectable		 3u8qA-1jhdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 LEU A 230
LEU A 229
GLN A 199
VAL A 226
ARG A 284
 None
None
BR  A2008 (-4.0A)
None
None
 1.40A 3zqtA-1jhdA:
undetectable		 3zqtA-1jhdA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		3 / 3 LEU A  86
GLU A  88
SER A  37
 None
None
BR  A2007 ( 3.9A)
 0.75A 4ccqA-1jhdA:
0.7		 4ccqA-1jhdA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 5 THR A 179
GLY A  50
PRO A  12
TYR A  16
 None
 1.05A 4grkA-1jhdA:
0.0		 4grkA-1jhdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 7 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.04A 4hajA-1jhdA:
undetectable		 4hajA-1jhdA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 7 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.03A 4hbfA-1jhdA:
0.0		 4hbfA-1jhdA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 7 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.06A 4hc3A-1jhdA:
undetectable		 4hc3A-1jhdA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		6 / 12 LEU A 230
LEU A 229
GLN A 199
VAL A 226
ARG A 284
ILE A 238
 None
None
BR  A2008 (-4.0A)
None
None
None
 1.42A 4ok1A-1jhdA:
undetectable		 4ok1A-1jhdA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 8 LEU A  55
MET A 131
LEU A  84
ILE A 117
 None
 0.90A 4ok1A-1jhdA:
undetectable		 4ok1A-1jhdA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		6 / 12 LEU A 230
LEU A 229
GLN A 199
VAL A 226
ARG A 284
ILE A 238
 None
None
BR  A2008 (-4.0A)
None
None
None
 1.45A 4oktA-1jhdA:
undetectable		 4oktA-1jhdA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 MET A  46
VAL A  45
GLY A  42
ALA A  41
SER A  38
 None
None
None
None
BR  A2007 (-4.8A)
 1.07A 4rrwA-1jhdA:
undetectable		 4rrwA-1jhdA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 MET A  46
VAL A  45
GLY A  42
ALA A  41
SER A  38
 None
None
None
None
BR  A2007 (-4.8A)
 1.06A 4rrwB-1jhdA:
0.0		 4rrwB-1jhdA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 MET A  46
VAL A  45
GLY A  42
ALA A  41
SER A  38
 None
None
None
None
BR  A2007 (-4.8A)
 1.07A 4rrzA-1jhdA:
undetectable		 4rrzA-1jhdA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 12 MET A  46
VAL A  45
GLY A  42
ALA A  41
SER A  38
 None
None
None
None
BR  A2007 (-4.8A)
 1.06A 4rrzB-1jhdA:
0.0		 4rrzB-1jhdA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		3 / 3 ASP A   8
ASN A 286
GLN A 285
 SO4  A1001 (-3.8A)
None
None
 0.56A 5k7uA-1jhdA:
undetectable		 5k7uA-1jhdA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 6 GLY A 145
THR A 148
GLN A  39
TYR A 136
 None
BR  A2007 ( 4.6A)
None
None
 1.15A 6ag0A-1jhdA:
undetectable		 6ag0A-1jhdA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		4 / 6 GLY A 145
THR A 148
GLN A  39
TYR A 136
 None
BR  A2007 ( 4.6A)
None
None
 1.11A 6ag0C-1jhdA:
undetectable		 6ag0C-1jhdA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_B_GM4B301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1jhd SULFATE
ADENYLYLTRANSFERASE
(Sulfur-oxidizing
endosymbiont
of
Riftia
pachyptila) 		5 / 11 VAL A  83
ALA A  64
LEU A 279
ALA A  67
LEU A  73
 None
 1.46A 6dk1B-1jhdA:
undetectable		 6dk1B-1jhdA:
18.80